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RISS 인기검색어
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- 저자 : 문종운(Jong Woon Moon) (검색결과 8 건)
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Lymphoscintigraphy에 이용되는 방사성의약품의 사용제한으로 인한 대체 방사성의약품의 성능평가
서영덕,정재훈,문종운,윤상혁,김영석,강세훈,원우재,김석기,Seo, Young-Deok,Jeong, Jae-Hun,Moon, Jong-Woon,Yun, Sang-Hyeok,Kim, Yeong-Seok,Kang, Se-Hun,Won, Woo-Jae,Kim, Seok-Ki 대한핵의학기술학회 2009 핵의학 기술 Vol.13 No.1
Purpose: Several radioactive agents were used for lymphoscintigraphy in breast cancer. But recently, due to the change of local radiopharmaceutical licensing policy and discontinuation of supplies from manufacturer, we could not use many radiocolloids such as $^{99m}Tc$-Antimony Trisulfide Colloid, $^{99m}Tc$-Tin Colloid, $^{99m}Tc$-Human Serum Albumin. So it is necessary to use the substitution radiopharmaceutical. Therefore, this study aims to evaluate the performance of substitution radiopharmaceutical ($^{99m}Tc$-Phytate) including the existing radiocolloids and to set up of the appropriate protocol in lymphoscintigraphy. Materials and Methods: For each radiocolloids ($^{99m}Tc$-Antimony Trisulfide Colloid (ASC), $^{99m}Tc$-Tin Colloid (TC), $^{99m}Tc$-Human Serum Albumin (HSA), $^{99m}Tc$-Phytate) were performed the particle size by Zeta Sizer (Nano-ZS) and we compared the radiolabeling time, procedure and acquisition time for each of the radiocolloids (total 200 patients). For the last time, we made an analysis of image for each of the radiocolloids with our previous report (SJ Jang et al, Korean Nucl Med Mol imaging Vol.41, No.6, Dec 2007). Results: The particle size of each radiocolloids showed A.S.C (50 nm), T.C (310 nm), H.S.A (10.8 nm), $^{99m}Tc$-Phytate (499 nm). The labeling and acquisition time for each of the radiocolloids showed no substantial difference. But there is difference of the labeling time for the A.S.C. because the ASC procedure need to boiling process. There were no significant differences among those radiocolloids (p>0.005) in the identification rate (IR), false negative rate (FNR), and negative predictive value (NPV). Conclusions: $^{99m}Tc$-labeled radiocolloids showed equivalent results in lymphoscintigraphy. Therefore, in this exam of each radiocolloids could be applied appropriate protocol in lymphoscintigraphy.
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PEM 수전해의 성능 향상을 위한 flow channel 설계
김성근(Seong Keun Kim),문종운(Jong Woon Moon),정성용(Sung Yong Jung) 대한기계학회 2021 대한기계학회 춘추학술대회 Vol.2021 No.11
PEMWE (proton exchange membrane water electrolyzer) uses a polymer electrolyte membrane as an electrolyte and requires high manufacturing costs because precious metals are used as catalysts. Accordingly, many studies are being conducted to increase the hydrogen production efficiency of PEMWE. A general PEMWE uses a titanium mesh as a PTL (porous transport layer) for a constant current supply. However, the mesh disturbs the water contaction to the electrolyte membrane because the produced gas during the chemical reaction is not smoothly discharged. Therefore, this study compared the performance with various flow channel designs to improve gas reduction and water supply. Three types of flow channels, including serial type, parallel type, and dual-channel type, were designed and compared their performances. Water was supplied at 15 mL/min, 90 °C, and performances were measured with current densities ranging from 0 A/cm² to 0.8 A/cm². At a current density of 0.8 A/cm², the basic type was 3.80 V, the serial type was 3.13 V, the parallel type was 3.39 V and the dual-channel type was 3.27 V. The serial type has the best performance because gas discharge is more active than other flow channels.
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김윤철,유연욱,서영덕,문종운,김영석,원우재,김석기,Kim, Yun-Cheol,Yu, Yeon-Uk,Seo, Young-Deok,Moon, Jong-Woon,Kim, Yeong-Seok,Won, Woo-Jae,Kim, Seok-Ki 대한핵의학기술학회 2010 핵의학 기술 Vol.14 No.1
현재 우리나라 암발생률을 보면 유방암과 갑상샘암이 매년 빠르게 증가하고 있는 추세이다. 따라서 I-131 scan과 전초림프절 검사인 lymphoscintigraphy가 많이 시행되고 있다. 그러나 이러한 검사는 전통적인 핵의학 영상 검사들과 마찬가지로 병리생태를 영상화하는 데에는 탁월하나 해부학적 정보는 많지 않다. 따라서 트랜스미션 스캔을 실시하여 해부학적 위치를 찾는 데 도움을 주는 등 여러 방법을 사용하고 있으나 만족스럽지 못하다. 이에 착안하여 감마실사영상의 fusion으로 좀 더 해부학적 정보가 많은 영상을 구현하고자 한다. 2009년 4월부터 7월까지 본과를 내원하고 SIEMENS사의 Symbia Gamma Camera를 이용하여 lymphoscintigraphy를 시행한 환자와 I-131 추가 검사를 시행한 환자를 대상으로 하였다. 먼저 감마카메라로 촬영한 후 촬영실 천정에 설치한 hyVISION사의 소형카메라(R-2000)로 동일 위치를 촬영하여 감마영상과 소형카메라의 실사영상을 자체개발한 Gamma Ray Tool Fusion 프로그램을 이용하여 fusion하여 일치도를 평가 하였으며, 환자 및 술자의 피폭선량을 평가하였다. 술자와 환자의 피폭선량은 트랜스미션 스캔을 적용하기 위한 플러드 선원의 제작과정과 실제 트랜스미션 스캔이 적용될 때 방사선피폭이 발생되며 술자의 방사선피폭은 평균 14.1743 ${\mu}Sv$이며, 환자의 방사선피폭은 평균 0.9037 ${\mu}Sv$이다. 또한 fusion 영상에서 감마마커와 실사마커가 일치하였고 플러드 선원에 의한 피폭은 없었다. 본원에서 구축한 감마영상과 실사영상의 fusion 프로그램으로 보다 많은 해부학적 정보를 포함하고 있는 영상을 임상의 및 판독의에게 제공할 수 있고, 업무프로세스가 감소되어 편리한 조작이 가능하게 되었다. 또한 플러드 선원에 의한 피폭을 줄일 수 있어서, 다른 핵의학 검사에도 사용이 가능할 것으로 생각되어진다. 하지만 환자의 사생활이 존중되어야 하기 때문에 검사시행 전, 검사진행 과정과 장점 등을 자세하게 설명한 후 환자가 동의할 경우 검사를 실시하여야 할 것이다. Purpose: Recently, South Korea has seen a rapidly increased incidence of both breast and thyroid cancers. As a result, the I-131 scan and lymphoscintigraphy have been performed more frequently. Although this type of diagnostic imaging is prominent in that visualizes pathological conditions, which is similar to previous nuclear diagnostic imaging techniques, there is not much anatomical information obtained. Accordingly, it has been used in different ways to help find anatomical locations by transmission scan, however the results were unsatisfactory. Therefore, this study aims to realize an imaging technique which shows more anatomical information through the fusion of gamma and realistic imaging. Materials and Methods: We analyzed the data from patients who were examined by the lymphoscintigraphy and I-131 additional scan by Symbia Gamma camera (SIEMENS) in the nuclear medicine department of the National Cancer Center from April to July of 2009. First, we scanned the same location in patients by using a miniature camera (R-2000) in hyVISION. Afterwards, we scanned by gamma camera. The data we obtained was evaluated based on the scanning that measures an agreement of gamma and realistic imaging by the Gamma Ray Tool fusion program. Results: The amount of radiation technicians and patients were exposed was generated during the production process of flood source and applied transmission scan. During this time, the radiation exposure dose of technicians was an average of 14.1743 ${\mu}Sv$, while the radiation exposure dose of patients averaged 0.9037 ${\mu}Sv$. We also confirmed this to matching gamma and realistic markers in fusion imaging. Conclusion: Therefore, we found that we could provide imaging with more anatomical information to clinical doctors by fusion of system of gamma and realistic imaging. This has allowed us to perform an easier method in which to reduce the work process. In addition, we found that the radiation exposure can be reduced from the flood source. Eventually, we hope that this will be applicable in other nuclear medicine studies. Therefore, in order to respect the privacy of patients, this procedure will be performed only after the patient has agreed to the procedure after being given a detailed explanation about the process itself and its advantages.
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표면 개질 및 형상 변화에 의한 산업용 안개 포집 성능 향상 연구
김지연(Ji Yeon Kim),문종운(Jong Woon Moon),강종훈(Jong Hoon Kang),정성용(Sung Yong Jung) 대한기계학회 2020 대한기계학회 춘추학술대회 Vol.2020 No.12
The water shortage problem has reached a serious level around the world, and various studies are being conducted to solve this problem. A simple, economical approach to solving this water shortage problem is to collect fresh water from fog. Although industrial cooling towers that produce large amounts of fog plumes are water harvesting resources, previous studies have been focused on collecting fresh water in nature. In this study, we proposed and tested several methods for improving the water collection efficiency in industrial. The fog screen structure was changed from a flat to concave shell in order to increase the drag coefficient. Also, side walls were installed to further improve fog collection efficiency by collection water droplets from the deflection, vortex flows. The most effective method was switch the discharged direction that reduce the draining loss. This study is expected to be useful in fog-harvesting screen design in various industrial fields.
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