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심박수 적응형 심박 조율 알고리즘 설계 및 평가: 시뮬레이션 연구
명현석,이경중 대한의용생체공학회 2019 의공학회지 Vol.40 No.1
In this study, we designed a blending algorithm for rate adaptive pacing for cardiac pacemaker. Generally, rate adaptive pacing (RAP) is applied to patients whose heart rate does not rise during exercise for chronotropic incompetence (CI) patient. It is very important to develop an algorithm for RAP that can be properly applied to CI patients. In order to design an RAP algorithm we used dual sensors. Firstly, we designed a bio-signal measurement system based on the dual sensors, which are accelerometer and respiratory system. Secondly, we conducted treadmill test for the simulation experiment while using 3-lead ECG as reference. Finally, we designed a blending algorithm based on activation state of the dual sensors. The proposed blending algorithm was subdivided into three sections based on the accelerometer signal, which are rapidly increased section (W1), hardly changed section (W2), and decreased section (W3). Each weight is set aside for each section. To evaluate this algorithm, ten healthy adult males were participated. The correlation and Root Mean Square Error between the proposed algorithm and the reference were compared, and shown to be r=0.88 and 2.82 bpm, respectively. These results show that the proposed blending algorithm of dual sensors enables proper tracking of the heart rate during exercise. Also, it shows the possibility that the proposed blending algorithm can be applied to improve quality of life of the chronotropic incompetence patient.
명현석(Hyoun-seok Myoung),이효기(Hyo-ki Lee),이경중(Kyoung-joung Lee),권오윤(Oh-yun Kwon) 대한전기학회 2006 대한전기학회 학술대회 논문집 Vol.2006 No.10
In this study, we designed a digital inclinometer to measure the angle and acceleration signals. Digital inclinometer consists of a tilt sensor, accelerometer, one-chip micro controller and BlueTooth module. Using the developed system, we made an experiment with Roll. The subject is laid on the Roll and rises each fool. 90° and 45° up, and measures angle and acceleration signals with 100㎐ sampling frequency. Through several tests, we could find the possibilities and usefulness which can evaluate normality / abnormality of body posture objectively.
피하에 효과적인 열 자극을 위한 고주파 자극 프로토콜 개발
명현석(Hyoun Seok Myoung),이대원(Dae Won Lee),김한성(Han Sung Kim),이경중(Kyoung Joung Lee) 대한전자공학회 2012 전자공학회논문지 Vol.49 No.10
뜸은 질병에 대한 면역력을 높이고 질병을 치유하는데 효과적인 반면 뜸의 열 자극 세기를 조절하기 힘들어 피부에 고통을 유발시키며 화상을 입히는 부작용이 발생된다. 이런 한계점을 극복하기 위해 자극 조절이 가능한 고주파 열 자극 시스템을 개발하였으며, 동물에게 뜸질을 할 경우 얻어지는 온도분포와 유사한 자극 프로토콜을 개발하였다. 자극을 위한 시스템은 2MHz, 200W의 고주파유전가열장치, 절연프로브, 절연플레이트, 음압 발생부 및 온도측정부로 구성되어있다. 자극 프로토콜 설계를 위해서 일차적으로 토끼의 대퇴부에 뜸질시 표피, 피하 5mm와 피하10mm에서 온도분포를 획득하였다. 획득된 뜸질의 온도분포와 유사한 온도분포로 자극하기 위해서 자극펄스의 duty ratio와 반복회수 및 출력을 제어하였다. 뜸질과 고주파 자극시 피하의 온도분포를 비교해본 결과 피하 5mm와 10mm 부위에서의 상관관계는 각각 95%와 91%로 일치함을 보여주었다. 또한, 고주파 자극시 표피에서의 온도분포는 뜸에 비해 현저하게 낮게 나옴을 확인하였다. 이를 통해 고주파 열 자극 시스템은 뜸질의 문제점인 화농, 물집과 같은 부작용을 유발시키지 않으면서 피하에 뜸질과 유사한 열 자극이 가능함을 보여주었다. Moxibustion is utilized not only to cure disease but also to increase immunity. However, it may lead to undesired effects including severe pains(blisters and burns) because of the difficulty of controlling heat intensity. To overcome these problems we developed the RF heat stimulation system which can control stimulus. Also, we developed the RF stimulation protocol for effective heat transfer in subcutaneous tissue of rabbit. RF stimulator consists of a medical RF capacitive heating device, isolation probe, isolation plate, negative pressure control part and temperature measurement part. For the designed stimulus protocol, we measured the temperature distribution on epidermis and in subcutaneous(5mm, 10mm) area of rabbit during moxibustion. A stimulation protocol was designed by controlling the ON/OFF duty ratio, repeating number, and energy of applied pulse to get the temperature distribution similar with that by moxibustion. In results, the correlation coefficients between temperature distribution by moxibustion and that of stimulator were 95% and 91% from 5mm and 10mm thick respectively. However, temperature distribution on epidermis by stimulator was remarkably lower than that of the moxibustion. Finally, the RF stimulation system showed that it can not only transfer effectively heat similar with moxibustion to the subcutaneous area, but also the influence by unwanted side effects can be minimized.
명현석(Hyoun-Seok Myoung),이효기(Hyo-Ki Lee),이경중(Kyoung-Joung Lee),권오윤(Oh-Yun Kwon) 대한전자공학회 2008 電子工學會論文誌-SC (System and control) Vol.45 No.1
본 논문에서는 롤(Roll)에 누워 있는 피검자의 각도와 가속도 신호를 측정하기 위한 디지털 경사계 설계하였다. 개발된 시스템은 기울기 센서(tilt sensor), 2축 가속도 센서(biaxial accelerometer), 마이크로프로세서(single chip microprocessor)와 블루투스(BlueTooth module)로 구성된다. 개발된 디지털 시스템은 다루기 쉽고 쉽게 착용 할 수 있다. 시스템을 성능을 평가하기 위해서 Roll위의 3명의 피검자로부터 각도와 가속도 신호는 ZEBRIS와 디지털 경사계에 의해서 동기화하여 측정하였다. 측정된 신호는 정량적인 방법에 의해서 처리되며 그때의 상관계수가 0.93임을 보여 준다. 이와 같은 결과로부터 디지털 경사계는 몸의 움직임을 평가하는데 유용할 것으로 보여 진다. In this paper, a digital inclinometer to measure the angle and acceleration signals of subject laid on Roll was designed. The designed system consists of a tilt sensor, biaxial accelerometer, single chip microprocessor and Bluetooth module. The designed digital inclinometer was easy to handle and to wear. To evaluate the performance of the system, we measured simultaneously the angle and acceleration signals from the 3 subjects on the Roll using two instruments which are ZEBRIS and designed system. The measured signals were processed by statistical method and then the correlation coefficient of 0.93 was shown. From the results, the designed digital inclinometer is shown to be useful in assessment of body movement.
명현석(Hyoun-seok Myoung),이효기(Hyo-ki Lee),이경중(Kyoung-joung Lee),권오윤(Oh-yun Kwon) 대한전기학회 2007 대한전기학회 학술대회 논문집 Vol.2007 No.4
In this paper, a digital inclinometer to measure the angle and acceleration signals of subject laid on Roll was designed. The designed system consists of a tilt sensor, biaxial accelerometer, microcontroller and Blue Tooth module. The designed digital inclinometer was easy to handle and easy to wear. To evaluate the performance of the system, we measured simultaneously the angle and acceleration signals from the 3 subjects on the Roll with two instruments which are ZEBRIS and our system. The measured signals were processed by statistical method and then the correlation coefficient of 0.93 was shown. From the results, the designed digital inclinometer is shown to be useful in assessment of body movement.