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이원종(Won Jong Lee),손병철(Byung Cheol Sohn),김행수(Haeng Soo Kim),양정인(Jeong In Yang),양성천(Seong Cheon Yang),조미영(Mi Yeong Jo),류종만(Jong Man Ryou),오기석(Kie Suk Oh),유희석(Hee Sug Ryu) 대한산부인과학회 2002 Obstetrics & Gynecology Science Vol.45 No.1
Objective : To evaluate perinatal outcomes in patients with abnormal 50 gm challenge test followed by normal 100 gm oral glucose tolerance test (OGTT) value. Methods : We examined the pregnancy outcomes of 423 women classified as the study group with abnormal 50 gm oral glucose challenge test (OGCT) followed by normal 100 gm OGTT based on NDDG criteria. If the 1-hour plasma glucose value of 50 gm OGCT was over 130 mg/dL, the patient was scheduled for a full 3-hour 100 gm OGTT. 50 gm OGCT and 100 gm OGTT were administered at 24-28 and 28-32 weeks' gestation, respectively. The control group constituted of 467 age- and body mass index (BMI)-matched negative screenees. We defined poor maternal outcomes as those suffering from any one of hydramnios or oligohydramnios, preeclampsia, cesarean delivery due to cephalopelvic disproportion, dystocia, or fetal distress. We also defined poor neonatal outcomes as those suffering from any one of hyperbilirubinemia, hypoglycemia, congenital anomaly, admission to neonatal intensive care unit due to respiratory distress syndrome, or perinatal mortality. Retrospective review of outcomes of these patients was performed. Student t-test, Fisher's exact test and chi-square test were used to determine the statistical significance. Results : There were no significant differences in demographic and obstetric characteristics between the control group and the study group. There were no significant differences in gestational age (38.7±1.5 vs 38.5±1.5 weeks), birth weight (3189.2±420.9 vs 3236.7±423.1 gm), between the groups. And there were no significant differences in preterm birth (6.2% vs 7.4%), large for gestational age births (4.5% vs 5.0%), intrauterine growth restriction (5.4% vs 4.3%) between the groups. There were no significant differences in poor maternal outcomes (15.6% vs 18.7%) and poor neonatal outcomes (3.9% vs 5.7%) between the groups. Conclusion : We conclude that abnormal value on 50 gm challenge test followed by normal 100 gm OGTT is not associated with adverse perinatal outcomes
한성철,류종서,이기영,김도만,최춘순 全南大學校 觸媒硏究所 2003 觸媒硏究 論文集 Vol.24 No.-
We studied the oxidation of docosahexaenoic acid(DHA: C22: 6ω-3). β-Cyclodextrin(CD) inclusion complexes(ICs) of DHA were prepared with antioxidant such as α-tocopherol and BHT, and microcapsulated with Curdlan and Pullulan. Identification of their structural features of ICs were observed with the use of SEM, FTR, and XRD. Methods for quantitative analysis of DHA were used: TLC scanning method and TBARS(Thiobarbituric acid reactive substance) method. As a result, we observed the formation of ICs and estimated antioxidant effect. In this work, loading efficiency of DHA in ICs was about 25%, and the antioxidant effect of α-tocopherol was higher than that of BHT. When ICs containing DHA was microcapsulated with curdlan and pullulan, the loading efficiency was less than 5%.