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        출생시 쌍태아간의 체중 차이에 따른 예후 비교

        임지은 ( Ji Eun Lim ),박성훈 ( Sung Hoon Park ),조권문 ( Kwon Moon Cho ),설현주 ( Hyun Ju Sul ),김탁 ( Tak Kim ),김해중 ( Hai Joong Kim ),강재성 ( Jae Sung Kang ),라중열 ( Joong Yol Na ) 대한산부인과학회 2003 Obstetrics & Gynecology Science Vol.46 No.3

        목적 : 쌍태임신은 불임시술의 발달과 더불어 증가하여 전체임신의 3%에 달하며 임신중의 합병증이 증가하는 고위험 임신이다. 합병증을 증가시키는 여러 위험인자 중 쌍태아간의 체중의 차이가 주산기 예후 및 모체에 끼치는 영향 등을 조사하여 임상적인 중요성을 알아보고자 하였다. 연구 방법 : 1992년부터 2001년까지 고려대학교 의료원 안산병원에서 분만한 157건의 분만을 대상으로 의무기록을 후향적으로 검토 분석하였다. 체중의 차이는 15% 미만을 보이는 Objective : The aim of this study was to determine clinical significance of weight difference in twin pregnancies. Methods : The medical records of 157 sets of twin pregnancies delivered between 1992 and 2001 were reviewed retrospectively. Birth weight di

      • Prostaglandin E₂의 子宮內 投與가 家兎의 卵巢機能에 미치는 影響에 關한 實驗的 硏究

        崔鏡淑,羅重烈,李壽鍾 고려대학교 의과대학 1983 고려대 의대 잡지 Vol.20 No.3

        The effects of intra-uterine administration of Prostaglandin-E₂on the ovary and plasma steroid hormones were studied. Pseudopregnancy was induced in seven rabbits by the injection of 50㎍ of ethinyl estradiol and 100IU of hCG subcutaneously. And these seven pseudopregnant rabbits served as control group. In the prostaglandin-E₂ was implanted in uterus on Day seven under laparotomy and uterine incision with pentothal anesthesia. The plasma estrogen and progesterone level was determined by radioimmunoassay with three days interval in both control and prostaglandin=E₂ treated group. The uterus and ovaries were submitted to histologic study on Day 30. The following results were obtained; 1. Serum progesterone level in intra-uterine prostaglandin-E₂-implanted pseudopregnant rabbits was decreased at 14th day of pseudopregnancy, while the progesterone level of normal pseudopregnant rabbits was decreased from 15th day of pseudopregnancy and returned to normal values by 18th day. 2. Serum estrogen levels of pseudopregnant rabbit was higher than pretreatment state and returned to normal value by 30th day, while, in prostaglandin-E₂treated group, the serum estrogen values was decreased at 11th and 18th day below the level of pretreatment state and it was more decreased at 28th day. 3. The corpus luteum regresses from 15th day in control group, but in prostaglandin-E₂ Treated group, the corpus luteum was indistinct. The numbers of follicles in control group were 4-5 in number, while, in prostaglandin-E₂treated group, they were increased to 7-11 in number. The endometrium was papillary secretory patterns in control group, while, in prostaglandin-E₂ treated group, the endometrium was shown to have proliferative patterns.

      • 子宮摘出이 家兎 卵巢의 機能에 미치는 影響에 關한 實驗的 硏究

        金善行,羅重烈,李壽鍾 고려대학교 의과대학 1983 고려대 의대 잡지 Vol.20 No.3

        To understand effects of hysterectomy on the retained ovarian function in the rabbits, pseudopregnancy was induced in seven rabbits, control group, by injection of 50㎍ of ethinyl estradiol and 100 IU of hCG subcutaneously. And a week after hysterectomy of another seven rabbits, hysterectomized group, pseudopregnancy was induced with 50㎍ of ethinyl estradiol and 100 IU of hCG. The serum levels of progesterone and estrogen were determined every 3 day by radioimmunoassay and microscopic examination of the ovaries was performed in each group. Both findings in each group was compared and obtained following results. 1. Luteal phase in hysterectomized group was prolonged about 6 days compared to control group. 2. Histologic examination of ovaries revealed functional corpora lutea in hysterectomized group up to 30 days of experiment. 3. Serum estradiol level and histological picture of the ovarian follicles showed no significant differences between two groups during experiment. 4. These findings show that experimental hysterectomy has inhibitory effect on regressive change of the corpora lutea but has no effect on ovarian follicle. These results suggest that PG is the luteolytic hormone in the rabbit. But, it was presumely concluded that the result in estrogen showed which PGF₂α or some other substances in the uterus might be related to the mechanism of folliculogenesis in ovary according to references.

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