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『상한론(傷寒論)』 변병진단체계(辨病診斷體系)에 근거하여 오령산(五笭散) 투여 후 호전된 미주신경성 실신 증례 보고 1례
두인선 ( In-sun Doo ),이성준 ( Sung-jun Lee ) 대한상한금궤의학회 2020 대한상한금궤의학회지 Vol.12 No.1
Objective: This case report presents the effect of Oryeong-san on vasovagal syncope. The patient was diagnosed with Grater Yang disease based on Shanghanlun provisions. Methods: According to the disease pattern identification diagnostic system based on Shanghanlun provisions (DPIDS), we diagnosed the patient as presenting Greater Yang disease. The patient was treated with Oryeong-san for 45 days. The change in symptoms was estimated based on VAS. Results: After treatment, the patient’s VAS score from 10 to 0 and he was completely cured. Conclusions: This case study shows the effectiveness of using Oryeong-san on vasovagal syncope according to DPIDS.
『상한론(傷寒論)』 변병진단체계(辨病診斷體系)에 근거하여 대청룡탕(大靑龍湯) 투여 후 호전된 충동 조절 장애 1례
두인선 ( In-sun Doo ),이성준 ( Sung-jun Lee ) 대한상한금궤의학회 2018 대한상한금궤의학회지 Vol.10 No.1
Objective : This case report presents the effect of Daecheongryong-tang on Impulse Control Disorder. The patient was diagnosed with Taeyang-byung based on Shanghanlun provisions. Methods : According to Shanghanlun six meridian patterns diagnostic system, we diagnosed the patient as Taeyang-byung and she has been suffering from impulse control disorder. The patient was treated with Daecheongryong-tang. And it was provided for 60 days. The changing symptom was estimated by Global Assessment of Functioning and Visual Analogue Scale. Results : After the treatment, the patient's functioning got better from 65 to 85 on GAF. And the degree of pain was reduced from 10 to 2 on VAS. Conclusions : This case study shows an effectiveness of using Daecheongryong-tang according to Diagnostic system based on Shanghanlun provisions on Impulse Control Disorder.
오미자(五味子)의 멜라닌 생성 억제와 미백효과에 관한 연구
두인선,임규상,황충연,박민철,김남권,Doo, In-Sun,Lim, Kyu-Sang,Hwang, Chung-Yeon,Park, Min-Cheol,Kim, Nam-Kwen 대한한방안이비인후피부과학회 2007 한방안이비인후피부과학회지 Vol.20 No.3
Objective : The aim of this study is to assess the effect of Schizandrae Fructus on melanin synthesis inhibition and whitening effect. Methods : We assessed inhibitory effects of Schizandrae Fructus on melanin-release from B16F10, on melanin production in B16F10, on mushroom tyrosinase activity in vitro, on tyrosinase activity in B16F10 and effect of Schizandrae Fructus on the expression tyrosinase, TRP-1, TRP-2, PKA, ERK-1 ERK-2, AKT-1, MITF in B16F10. Results and Conclusion : 1. Schizandrae Fructus inhibited melanin-release, melanin production in B16F10. 2. Schizandrae Fructus inhibited tyrosinase activity in vitro and in B16F10. 3. Schizandrae Fructus suppressed the expression of tyrosinase, TRP-1, TRP-2, PKA, ERK-2 in B16F10.
『상한론(傷寒論)』 태음병(太陰病)으로 진단된 신체증상장애 환자 7례 증례 보고
윤효중 ( Hyo-joong Yun ),하현이 ( Hyun-yee Ha ),두인선 ( In-sun Doo ),이숭인 ( Sung-in Lee ),이성준 ( Sung-jun Lee ) 대한상한금궤의학회 2021 대한상한금궤의학회지 Vol.13 No.1
Objectives: This study was conducted to confirm the reproducibility of the diagnosis of greater yin disease (太陰病) and the efficacy of herbal treatment using Gyejigajakyak-tang or Gyejigadaehwang-tang in somatic symptom disorder (SSD). We also further refined the characteristics of greater yin disease in SSD. Methods: We analyzed the demographic and treatment data of seven patients with SSD from four Korean medical clinics. The reliability of diagnosis and the efficacy of the treatments were evaluated by the Beck Anxiety Inventory (BAI), a numerical rating scale (NRS), and the patients’ statements. Finally, we analyzed patients according to the diagnostic points of Shanghanlun provision 273. Results: Seven SSD patients took Gyejigajakyak-tang or Gyejigadaehwang-tang. The mean age of the patients was 52.1±15.8 years old, and the herbal medication period was 82.2±38.2 days. At the first visit, the patients showed hypochondriasis, obvious stress, and a severe BAI score (40.4±10.9). The NRS significantly decreased from 8.9±1.6 to 0.7±0.7 after the treatments. There were no side effects reported. As a result of analyzing these 7 cases, hypochondriasis, obvious stress, and anxiety were identified, which had been previously suggested as 自痛, 因爾, and 結硬. Conclusions: We confirmed the reproducibility of greater yin disease in 7 SSD cases from 4 medical institutions. These results imply that there could be a considerable relation between SSD and greater yin disease as defined by the Shanghanlun provisions.