주사에 대한 색소레이저 ( Flashlamp - Pumped Pulsed Dye Laser ) 의 치료효과에 관한 연구

남종택(Jong Taik Nam),김기호(Ki Ho Kim),조광열(Gwang Yeol Joh) 대한피부과학회 1994 大韓皮膚科學會誌 Vol.32 No.4

Background : Persistent facial elangiectssia, erythema, and flushing are the major cosmetic problems in patients with rosacea, However various therapeutic modalities for roacea papules and pustules, including topical antibiotics, systemic antibiotics, isotretinoin, and systernic and topical metronidazole, are not effective in reducing telangiectasia and flushing reactions present inrosacea patients. The flashlamp-pumped pulsed dye laser has been deacribed as a succqssful treatment for port wine stains with telangiectasia as part of their abnomalities. A clinical study was therefore undertaken in a group of rosacea patients, who recieves this laser to areas of facial taieous lesions. Objective : The purpose of the study was to evaluate the therapeutic effect of the flashlamp-pumped pulsed dye laser(SPTL-1) for osacea, especially telangiectasia and flusing reactions. Methods : Forty-eight. patient with rosacea were studied to evaluatic the therapeutic effects of the SPTL-1 flashlamp-pumped pulsed dye laser (Candela corp.Wayland Mass.) at the Department of Dermatology in Dong-A University Hospital for 20 months from Januarg 1991 to August 1992. Results : 1. Total therapeutic effects of this SPTL-1 laser showed excellent re:ults in 22.9%, good in 62.5%, fair in 8.3%, and poor in 6.3%. 2. Therapeutic effects of rosacea-associated lesions showed exeellerit or good results in 85.4% of patient,s with erythema and telangiectasia, 84% patients with papules, 100% patients with pustules, and 93.7% of patients with facial flushing. 3. Complications included trarsient hyperpigmentation (14.6%), section lary bacterial infection(6.3%), hypopigmentation(2.1%), and atropic scar(2.1%). 4. The recurrence rat.e was 2,9,%. Conclusion : The flashlamp-pumped pulsed dye laser (SPTL-1) is a dry effective mode of treatment for rosacea, including persistent telangiectasia and facial flushing ri.actions which were intractable to previous other therapeutic modalities. (Kor J Dermatol 1994; 32(4): 649-654)

Befunolol Hydrochloride ( 0 . 5 % BentosR ) 에 의한 알레르기성 접촉피부염

남종택(Jong Taik Nam),김기호(Ki Ho Kim),조광열(Gwang Yeol Joh) 대한피부과학회 1994 대한피부과학회지 Vol.32 No.6

Befunolol hydrochloride is a B-adrenergic receptor antagonist cornnory used topically in treatment of glaucoma because of a satisfactory intraocular pressure lowering apcity without relevant topical or systemic side effects. We repart herein a case of allergic contact dermatit.is due to befunc ol nydrochloride in 0.5% Bentos eyedrops, A 52-year-old Korean woman had suffered from erythemanedema with itching sensation on her left eye since Novembeir 18, 1992. She had used various ophtalrnic preparations including Bentos eyedrops containing befinolol hydrochloride 0,5% as its activ cinstituent since October, 1992 for treatment of glaucoma of her left eye. Patch test with the European standard series, rubber series, the patiants eyedrops and their individual constituents showed positive. reactions only to 0.5% Bentos eyedrops(as is) and to befunolol hydrochloride. We noted rapid improvement of skin lesions and syipsms after the withdrawal of Bentos eyedrops and applicatior of another B-blocker(carteolol hydrocilcide). (Kor J Dermatol 1994; 32(6) 1142- 1146)

모반양 기저세포암 증후군 2예

조광열(Gwang Yeol Joh),남종택(Ki Ho Kim),김기호(Jong Taik Nam),김영수(Young Soo Kim),이봉구(Bong Ku Lee) 대한피부과학회 1992 대한피부과학회지 Vol.30 No.6

Nevoid basal cell carcinoma syndrome is inherited as an autcsonal dominant trait with a high degree of penetrane and variable expressivity. The mair features are basal cell carcinoma. jaw cysts, skeletal anornalies, ectopic calcifications and palmoplantar pits. We report varous clinical ma.nifestations in brother and sister, wnich are jaw cyst,, bifid rib, shortened fourth metacarpals, ectopie calcification, palrnoplanar pits and basal cell carcinoma, Microscopically, histologic patterns of basal cell cacinomas are superficial, nodulocystic, keratotic, pigmented, adenoid and follicullar nevoid. Lange numbers of basal cell carcinomas were electrodessicated and curetted under general,nesthesia. (Kor J Dermatol 1992;30(6):951-957)

Toxic Pustuloderma

윤정호(Jung Ho Yoon),남종택(Jong Taik Nam),김기호(Ki Ho Kim),조광열(Gwang Yeol Joh) 대한피부과학회 1994 대한피부과학회지 Vol.32 No.5

Generalized sterile pustular eruptions occur in various dermatoses including pustular psoriasis, erythema multiforme, Sneddon-Wilkinsan disease and others. Recentlr, acute eruptions of disseminated sterile pustules have been reported. The etiology is not related to a gepetic predisposition to psoriasis but to drug ingestion or viral infections, thus termed toxic pustuloderm; (T. P.). In this report, we present a typical case of T. P. observed iu our department. Our patient, an 18-year-old male, with no personal or family history of psoriasis, was given drug medication including amoxicillin for fever and chilling sensation. Pustilar eruptions first, appeared on his face about two days aft.er the medication and gradually spread to the trunk and limbs. The skin examination revealed numerous small pustules on an erythematous base. Laboratory examination revealed neutrophilic leukocytosis and an elevated sedimentation rate skin biopsy showed subeorneal and spongiform neutrophilic pustules Upon interruption of the amoxicillin, the pustules cleared rapidly in 3 days and there has been ri.o recui rence of any rash over a 7-month follow-up period. (Kor J Dermatol 1994;32(5):944-949)

만성 일광 피부염

김기호(Ki Ho Kim),남종택(Jong Taik Nam),조광열(Gwang Yeol Joh) 대한피부과학회 1992 대한피부과학회지 Vol.30 No.6

Chronic actinic dermatitis was recently proposed to be a syndrome of chronic photosen-sitivity that incudes photosensitive eczema, persitent light reection, photosensitivity dermatitis and actinic reticuloid. We report herein a case of chronic actinic dermatitis which occured in a 60-year-old man. He suffered from a chronic eczematous dermatitis affecting e posed skin and some covered area with a feature of erythroderma. Phototesting showed abnormal photosensitivity to both UVB and UVA as will as to visible light. Skin biopsy specimes revealed histologic findings of spongiotic dermatitis in which dermal infiltrates were mainy consisted of T lymphocytes with suppressor T cells dominance on immunohistochemistry. (Kor J Dermatol 1992;30(6):908-912)

적외선 분광법에 의한 알루미나의 OH 특성 연구

김종택,김명철,남우현 한국화학공학회 1987 Korean Chemical Engineering Research(HWAHAK KONGHA Vol.25 No.3

여러 온도에서 열처리한 베마이트의 스펙트럼상의 OH 흡수띠들을 컴퓨터 프로그램의 최적화 방법으로 분해했다. 베마이트의 분해된 OH 띠들은 2700-2720㎝^(-1)(띠 1), 2906-2914㎝^(-1)(띠 2), 3064-3072㎝^(-1)(띠 3), 3255-3269(띠 4), 3417㎝^(-1)(띠 5)에서 가장 큰 흡수를 갖는 것으로 나타나는 5개의 특징적인 OH 기들로 되어 있었다. 띠 1과 2는 수화된 알루미늄 양이온의 OH기들에 의한 대칭 및 비대칭신축진동에 의한 흡수띠로 여겨진다. 띠 3과 4의 흡수는 알루미나 층사이에 위치한 구조적인 기들에 의한 것으로 생각된다. 그리고 띠 5는 알루미늄에 붙어있는 단일 OH결합에 의한 것으로 여겨진다. The OH absorption bands of boehmite on the infrared spectra obtained at the various temperatures were deconvoluted by the simplex method of computer program. The deconvoluted bands of boehmite corresponded to five specific OH groups appeared to have band maxima at 2700-2720 ㎝^(-1) (band 1), 2906-2914 ㎝^(-1) (band 2), 3064-3072 ㎝^(-1) (band 3), 3255-3269 ㎝^(-1) (band 4), 3417 ㎝^(-1) (band 5). The band 1 and 2 were assigned to the symmetric and asymmetric stretching vibrations of hydroxyl groups of hydrated aluminum cations. The absorptions of band 3 and 4 were assigned to the strutural hydroxyls located between the alumina layers. And the band 5 was assigned to the single OH attached to the aluminum.

석탄/B.C.油/水/尿/混合液의 燃料로서의 物性硏究

金淙澤,鄭盛旭,南雨鉉 慶北大學校 産業開發硏究所 1984 硏究報告 Vol.12 No.-

石油연료의 效果的 利用方案의 하나로 B.C.油에 물과 石炭을 混合하여 燃料로서의 物性을 硏究검토하였다. 이때 混合系의 安定을 爲하여 界面活性劑代身에 人尿를 添加하였다. 混合系의 粘度, 水滴의 粒度, 水泡의 成長, 層分離, 石炭의 沈降현상等을 관찰 또는 測定하여 安定性을 검토하였다. 물의 含量은 混合系의 安定에 절대적역할을 하고 있었으며 32% 以上 함유시 水泡의 巨大化와 層分離현상이 이러났다. 石炭의 混合은 25%까지 可能하였으나 水分含量이 적고 B.C.油가 많을수록 安定된 混合系를 形成하였다. 尿의 含量은 2∼3%前後가 適當한 量으로 나타났다. 이들 混合系는 大體 W/O 分散系였으며 石炭은 油內에 分散되어 있었고 尿는 油一水界面에서 계면활성역할을 나타내고 있었다. To improve the efficiency of B.C. oil fuel, we made a physico-chemical studies of oil/coal/water/urine mixtures as fuel. We used human urine as a surfactant for the mixture. Densities, viscosities, particle size of water drop, growth of water drop, layer separation and coal sedimentation in the mixture have been studied as a stability criteria of the dispersed systems. Water content of the mixtures worked as most important roles for the stability. The mixtures contained more than 32% indicated water drop growing or layer formation. The mixtures which contained coal up to 25% indicated farely good stability unless water amount did not prevailed adequate amount. 2∼3% of urine in the dispersed system was most optimum condition. Most of the mixtures were W/O type dispersion and the coal powder were distributed only in the oil media. Urine performed itself as a good stabilizer at the interface of oil and water.