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- 저자 : 김해엽(Hae Youp Kim) (검색결과 2 건)
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PCR 을 이용한 인슐린 수용체 β - 소단위의 DNA 측정에 관한 연구
최웅환(Woong Hwan Choi),유계수(Ge Soo Yoo),고근아(Keun Ah Koh),정형진(Hyung Jin Chung),김해엽(Hae Youp Kim),신현호(Hyun Ho Shin),한인권(In Kwon Han),문인걸(In Gul Moon) 대한내과학회 1991 대한내과학회지 Vol.40 No.6
N/A Insulin resistance is one of the most important mechanisms of type II diabetes, which may result from acquired or genetic abnormalities in the pathway of insulin action. As the develoment of cloning method of human insulin receptor precursor cDNA, it has become possible to investigate the insulin receptor at the genetic level. We used the modified PCR technique method that permitted us to employ small amounts of cellular RNA as the initial template to amplify the region that encodes the intracellar β-subunit of the human insulin receptor and C-terminal region of β-subunit. We think that this PCR method will facilitate a definite determination to what degree insulin resistance can be ascribed to genetic alterations in the structure of the insulin receptor molecule in type II diabetes.
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신현호,안용진,김해엽,정형진,조동희 대한감염학회 1991 감염 Vol.23 No.3
Infectious Mononucleosis (IM) is an acute, self limited, infectous disease, most frequently recognized as a clinical entity in adolescents and young adults and characterized by the presence of fever and evidence of lymphoid hyperplasia. These primary findings often are accompanied by pharyngitis, mild hepatic dysfunction. nonspecific rashes, hematologic abnormalities., and involvement and dysfunction of virtually all other organ systems. A 29-year-old man admitted to the hospital because of fever and sore throat. The patient is Swedish who came to Korea 80 days earlier, when fever was developed. 5 days before entry he experience sore throat and myalgia. On examination the patient was febrile. Both tosils were covered whitish exudate. Lymphadenopathy was found both cervical areas, axillay regions and inguinal areas. There was no hepatosplenomegaly. Peripheral blood smear showed atypical lymphocytes. The heterophil antibody titer was 1:896 and anti-VCA-IgM was positive.
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