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주진덕(Jin-Deok Joo),한정호(Jung Ho Han),김영훈(Young-Hoon Kim),김택균(Tackeun Kim),김재용(Chae-Yong Kim),오창완(Change Wan Oh),유정희(Jung Hee Ryu),전영태(Young Tae Jeon) 대한두개저학회 2012 대한두개저학회지 Vol.7 No.2
Objective : We searched the incidence of postoperative nausea and vomiting(PONV) after microvascular decompression(MVD), which might potentially results in an increased risk of postoperative intracranial hemorrhage and neurologic dysfunction. METHODS : Between 2004 and 2010, a total of 109 patients were diagnosed as having a neurovascular cross compression, and were treated with lateral suboccipital craniotomy with MVD. The incidence of PONV and the use of rescue antiemetics were identified at 1, 24 and 48 hours after surgery. RESULTS : Seventy-one(65.1%) patients were female, and the mean age of the patients was 49±10 years(range, 20~69). The overall incidence of development of PONV within postoperative 48 hours was 69.7%. The incidences of PONV at 1, 24, and 48 hours after surgery were 31.1%, 56.8%, 44.0%, respectively. PONV was most prevalent at 24 hours after surgery, and then the incidence decreased over time. In the early postoperative period, female was significantly more susceptible to PONV than male, especially at 1 hour after surgery(p=0.035). CONCLUSION : The incidence of PONV was high enough to be actively managed, especially within 24 hours after MVD. PONV was more prevalent in female in the early postoperative period.
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