증례 : 소화기 ; 재발성 공장염으로 나타난 발작성 야간혈색소뇨증 1예

김지원 ( Ji Won Kim ),김준영 ( Jun Young Kim ),김진혜 ( Jin Hae Kim ),김혜인 ( Hye In Kim ),김영남 ( Young Nam Kim ),김영호 ( Young Ho Kim ),홍성노 ( Sung Noh Hong ) 대한내과학회 2016 대한내과학회지 Vol.90 No.2

발작성 야간혈색소뇨증은 보체 매개성의 만성 혈관내 용혈, 야간 혈색소뇨, 혈전증, 골수부전을 특징으로 하는 매우드문 후천적 조혈모세포 질환이다. 혈전증에 의한 위장관 허혈증은 발작성 야간혈색소뇨증의 합병증으로 알려져 있으나 우리나라 성인에서 이에 대한 보고는 아직 없었다. 저자들은 재발성 공장염을 보인 발작성 야간혈색소뇨증 환자를 경험 하였기에 이를 보고하고자 한다. 원인이 명확하지 않은 공장염이 반복적으로 발생할 경우 드문 원인 중 하나로 발작성 야간혈색소뇨증을 고려해 볼 수 있을 것으로 생각한다. Paroxysmal nocturnal hemoglobinuria (PNH) is a rare acquired hematopoietic stem cell disorder characterized by chronic complement- mediated intravascular hemolysis, nocturnal hemoglobinuria, predisposition to thrombosis and secondary bone marrow failure. Small bowel ischemia is a complication of PNH but has not been reported to date in a Korean adult. We report here a case of PNH presenting as recurrent jejunitis. Despite the uncommon etiology, PNH should be considered in the differential diagnosis of patients with unexplained recurrent jejunitis. (Korean J Med 2016;90:132-135)

증례 : 순환기: 위출혈 환자에서 관상동맥중재술 직후 발생한 급성 스텐트혈전증 1예

김준영 ( Jun Young Kim ),김혜인 ( Hye In Kim ),김지원 ( Ji Won Kim ),김진혜 ( Jin Hae Kim ),김영남 ( Young Nam Kim ),송영빈 ( Young Bin Song ),김준수 ( June Soo Kim ) 대한내과학회 2016 대한내과학회지 Vol.90 No.4

급성 위장관출혈 및 흉통으로 내원한 59세 남자 환자에서 수혈 및 내시경지혈술을 시행하였고, 출혈이 멎은 뒤 3일 후 급성 관동맥증후군으로 관상동맥중재술을 시행하였다. 성공적인 중재술 직후 환자는 흉통을 호소하다가 맥박이 소실된 심실세동으로 제세동 및 경피적 심폐순환 보조장치를 삽입 하였다. 이후 시행한 관상동맥조영술에서 급성 스텐트혈전증을 진단하였다. 우리는 급성 관동맥증후군과 출혈이 동시에 발생할 경우 항혈소판제의 균형 있는 사용에 대해 신중한 선택이 필요하다는 것을 본 증례를 통해 확인하였고 이에 문헌고찰과 함께 보고하는 바이다. Stent thrombosis is a rare, but potentially catastrophic complication of stent implantation. Dual antiplatelet therapy with aspirin and a thienopyridine (clopidogrel, prasugrel, or ticagrelor) is essential to minimize the risk of stent thrombosis in patients receiving drug-eluting stents. However, there is an ongoing debate regarding antiplatelet therapy in patients presenting with acute coronary syndrome and bleeding. Here, we report a case of a 59-year-old man with acute stent thrombosis immediately after percutaneous coronary intervention combined with acute coronary syndrome and gastrointestinal bleeding. (Korean J Med 2016;90:322-325)

유륜에 발생한 후천성 국한성 림프관종

김진혜 ( Jin Hye Kim ),양윤석 ( Yoon Seok Yang ),조수익 ( Soo Ick Cho ),정보영 ( Bo Young Chung ),박천욱 ( Chun Wook Park ),이철헌 ( Cheol Heon Lee ),김혜원 ( Hye One Kim ) 대한피부과학회 2013 대한피부과학회지 Vol.51 No.6

Lymphangioma is an uncommon, benign hamartomatous malformation that consists of dilated lymphatic channels lined by normal, single-cell lymphatic endothelia. The lymphangiomas are divided into cavernous lymphangioma, cystic hygroma, lymphangioma circumscriptum, and acquired progressive lymphangioma. Acquired lymphangioma circumscriptum usually occurs due to surgery, infection or radiotherapy, which leads to obstruction of lymphatic vessels. Clinically, the lesions appear as thick-walled, 2∼5 mm translucent vesicles. Spontaneous drainage of straw-colored to milky-white fluids may occur. Herein, we report an acquired lymphangioma circumscriptum of the nipple areola without preceding causes.

성인 아토피피부염 환자의 삶의 질

김진혜 ( Jin Hye Kim ),김혜원 ( Hye One Kim ),박천욱 ( Chun Wook Park ),이철헌 ( Cheol Heon Lee ) 대한피부과학회 2011 대한피부과학회지 Vol.49 No.11

Background: The symptoms of atopic dermatitis (AD) may lead to the impairment of overall quality of life (QOL). Many international studies have addressed the effects of AD on the QOL of patients and their families`. However, studies from Korea are few and insufficient. Objective: The purpose of this study was to identify the correlation between the QOL and clinical disease severity in adults with AD. Methods: Thirty-one AD patients ranging in age from 19∼43 years were included. Dermatology Life Quality Index (DLQI) and the shorter version of World Health Organization QOL assessment instrument (WHOQOL-BREF) were used to determine the QOL. Eczema area and severity index (EASI) was examined to evaluate the severity of AD. Results: The mean DLQI, QOL and EASI score was 19.74±6.93, 3.77±0.76 and 9.42±11.12, respectively. DLQI and QOL scores significantly correlated with EASI score (p<0.05 for both). There was no significant correlation between DLQI and QOL score (p>0.05). Each domain of the WHOQOL-BREF and EASI score did not show meaningful correlation (p>0.05). However, for DLQI, categories of emotion, daily life, work and school work showed a high correlation with the EASI score (all p<0.05). Both DLQI and QOL score showed significant correlation with the EASI score in females (p<0.05), but only QOL score showed high correlation in male (p<0.05). Conclusion: AD affects QOL of adults with AD as the disease severity increases. In managing the AD patients, evaluating the clinical severity and evaluating QOL of patients would be necessary and emotional support will be helpful. (Korean J Dermatol 2011;49(11):983∼992)

인도적 체류지위의 정의규정에 관한 연구

김진혜(Kim, Jin-hye),조정현(Cho, Jung-hyun) 한국법학원 2020 저스티스 Vol.- No.180

한국은 1992년 난민의 지위에 관한 협약 에 가입하고, 2012년 국제법과 국내법의 조화, 인권선진국을 위한 초석 마련이라는 목적을 위하여 난민법을 제정하였다. 그러나 난민법이 제정·시행된 이후에도 낮은 난민인정률과 난민인정절차의 공정성에 대한 비판은 계속되고 있으며, 최근에는 인도적 체류의 대상에 무력충돌로 인한 유민이 포함되는지 여부도 문제되고 있다. 인도적 체류에 대한 위와 같은 논란은 난민법이 난민과 인도적 체류를 함께 규정하면서도 인도적 체류의 정의를 명확히 규정하지 않은 채 단순히 인도적 체류 허가를 받은 자, 즉 인도적체류자를 ‘난민에는 해당하지 않지만 고문 등의 비인도적 처우나 처벌 또는 그 밖의 상황으로 인하여 생명이나 신체의 자유 등을 현저히 침해당할 수 있다고 인정할 만한 합리적 근거에 기하여 법무부장관의 체류허가를 받은 외국인’이라고만 규정하고 있기 때문이다. 위 규정만으로는 ‘고문’, ‘비인도적 처우나 처벌’, ‘그 밖의 상황’을 특정할 수 없다. 나아가 인도적 체류의 국제법적 근거인 시민적·정치적 권리에 관한 국제규약 과 고문 및 그 밖의 잔혹하거나 비인도적 또는 굴욕적인 대우나 처벌의 방지에 관한 협약 이 난민법에 어떻게 반영되었는지도 알 수 없어, 국내법인 난민법이 국제조약인 위 인권조약들과 조화롭게 해석되기 어렵고, 이런 규정체계의 미비점은 실무상 혼란을 일으켜 보호가 필요한 외국인을 국제적 수준에서 제대로 보호하지 못하는 결과를 가져올 수 있는데, 이는 난민법의 제정취지와 맞지 않는다. 이런 문제점을 해결하기 위한 근본적인 방안은 난민법에 인도적 체류 중 고문, 비인도적 처우나 처벌, 그 밖의 상황에 대한 명확한 개념을 규정하여야 하고, 적어도 인도적 체류의 근거가 되는 국제조약을 명시하여야 하며, 최근 논쟁이 되는 무력충돌로 인한 유민이 인도적체류자에 포함될 수 있는지도 명확히 규정하여야 한다. Korea accessed to 「the Convention Relating to the Status of Refugees」 in 1992, and enacted its own Refugee Act in 2012 in order to harmonize domestic law with international law and protect human rights more effectively. However, even after the enactment and enforcement of the Refugee Act, there are still problems such as the low rate of refugee recognition and the unfairness of the refugee screening process. Furthermore, whether humanitarian status of the Refugee Act encompasses international displaced persons caused by armed conflicts is not clear because of the absence of regulations about the concept of humanitarian status. The Refugee Act prescribes that ‘humanitarian sojourner is a foreigner who is not eligible for refugee status, but who has rational grounds for recognizing that his or her personal liberty is very likely to be infringed by torture, other inhuman treatment or punishment or other events’, but does not denote the international law basis of humanitarian status, which includes 「the Convention against Torture and Other Cruel, Inhuman or Degrading Treatment or Punishment」and 「the International Covenant on Civil and Political Rights」. Besides, the Refugee Act has a problem that it does not provide clear definitions of ‘torture’, ‘other inhuman treatment or punishment’, and ‘other events’. This absence of regulations may result in the situation that the rights of asylum-seekers can not be properly protected under the Refugee Act. To solve the problems of the Refugee Act and to protect asylum-seekers in compliance with international human right law, it is necessary to insert more detailed concept provisions in the Refugee Act or, at least, specify the international treaties on which the humanitarian status is based. In addition, ‘other events’ should be defined as situations including armed conflicts.

교양체육 참여 대학생의 자아존중감과 심리적 행복감간의 관계

김진혜(Kim, Jin-Hye),전형상(Jeon, Hyeong-Sang),이지훈(Lee, Ji-Hoon) 한국체육과학회 2012 한국체육과학회지 Vol.21 No.3

The purpose of the following study was to examine the relationship between self-esteem and mental happiness of university students who participate in general physical education. In order to reach the main purpose of this study, we used convenience sampling of 285 students attending a 4-year university in the Seoul and Gyeong-Gi area The collected copies of the study were analyzed through a frequency analysis, primary factor analysis, t-test, one way ANOVA, correlation analysis, and multiple liner regression. Results derived from the above method and procedures are described as follows. Firstly, the study showed different results depending on gender, grade level, major of study, and salary of university students who participate in general physical education. Secondly, there were minimal or maximum relationships between the psychological happiness of university students who participate in general physical education and those students’ self-esteem. Overall, self-esteem had an influence on happiness which was effected by social life, family, and school.

양측 전경골근 탈출증

김진혜 ( Jin Hye Kim ),양윤석 ( Yoon Seok Yang ),조수익 ( Soo Ick Cho ),정보영 ( Bo Young Chung ),김혜원 ( Hye One Kim ),이철헌 ( Cheol Heon Lee ),박천욱 ( Chun Wook Park ) 대한피부과학회 2013 대한피부과학회지 Vol.51 No.10

Muscle herniation is defined as a protrusion of a portion of a muscle through a defect of the muscle fascia. The anterior tibialis muscle is the most common site of herniation. This condition is a relatively common complaint among athletes, and it has been frequently reported in the orthopedic surgery literature, whereas it has received little attention in the dermatological literature. Clinical findings include the presence of soft, compressible nodules that vary in size depending on their position. Usually, herniation is asymptomatic and the main concern is cosmetic, but the patient may seek medical treatment because of pain. Here we report a 65-year-old woman who visited our hospital for an evaluation of two asymptomatic nodules that were on her lower legs, and was diagnosed with bilateral tibialis anterior muscle herniation. (Korean J Dermatol 2013;51(10):806∼808)

수박과 멜론에 의해 유발된 구강 알레르기 증후군

김진혜 ( Jin Hye Kim ),양윤석 ( Yoon Seok Yang ),조수익 ( Spp Ick Cho ),박천욱 ( Chun Wook Park ),이철헌 ( Cheol Heon Lee ),김혜원 ( Hyeone Kim ) 대한피부과학회 2013 대한피부과학회지 Vol.51 No.9

Oral allergy syndrome (OAS) usually presents as an immediate swelling and itching sensation of the mouth and throat after ingestion of a food allergen. OAS may be the most common food allergy-related manifestation. Watermelon and melon belong to the Cucurbitaceae family and often show allergenic cross reactivity. Profilin is a 13 kda protein that is identified as a relevant pollen allergen in airborne pollen and related plant food allergies. Profilin is found in both watermelon and melon. Here we report a case of OAS to watermelon and melon in an 11year-old boy. He was positive to the skin prick test, patch test and oral challenge test with watermelon and melon.

비전형적인 임상양상을 보인 Palisaded Encapsulated Neuroma

조수익 ( Soo Lck Cho ),김진혜 ( Jin Hye Kim ),정보영 ( Bo Young Chung ),김정원 ( Jeong Won Kim ),김혜원 ( Hye One Kim ),박천욱 ( Chun Wook Park ),이철헌 ( Cheol Heon Lee ) 대한피부과학회 2012 대한피부과학회지 Vol.50 No.8

Palisaded encapsulated neuroma (PEN) is a rare, benign, cutaneous nerve sheath tumor, which usually appears as a solitary asymptomatic skin-colored papule, which usually affects the face of middle-aged adults. Here, we report a case of PEN with unusual clinical features in a 23-year-old female, developed on the back, accompanied with pain sensation. Histopathologically, it appeared as a well-circumscribed, encapsulated round nodule, consisted of uniform, broad, and interlacing fascicles of the spindle cells in the dermis. On immunohistochemical staining, the tumor cells of nodule were positive for S-100 protein and neural filaments, while the capsule of the nodule was focally positive for the epithelial membrane antigen.

소아청소년 아토피피부염 환자의 삶의 질

조수익 ( Soo Ick Cho ),김진혜 ( Jin Hye Kim ),정보영 ( Bo Young Chung ),안인수 ( In Su Ahn ),김혜원 ( Hye One Kim ),박천욱 ( Chun Wook Park ),이철헌 ( Cheol Heon Lee ) 대한피부과학회 2011 대한피부과학회지 Vol.49 No.5

Background: The symptoms of atopic dermatitis (AD) can limit a patient`s physical and psychosocial development as well as lower their overall quality of life (QOL). These problems may have a greater effect on patients during childhood and adolescence, whose physical and psychosocial developments are vigorously ongoing. Objective: The purpose of this study was to identify the correlation between the QOL and clinical disease severity in children and adolescents with AD. Methods: Forty-six AD patients aged from 7 to 18 years were included in this study. A questionnaire based on Children`s Dermatology Life Quality Index (CDLQI) was used to determine QOL. Eczema area and severity index (EASI) were examined to evaluate the severity of AD. Results: The mean score of CDLQI was 12.83±6.52. Among the 10 categories, itching, treatment, and sleep showed the highest scores, whereas teasing, friendships, and school or holiday work had the lowest scores (p<0.01). The mean EASI score was 8.51±8.64. CDLQI and EASI scores showed significant correlation (p<0.001). Among the 10 categories of CDLQI and EASI score, the sleep, itching, and clothes categories displayed high correlation with the EASI score (p<0.001). There was no statistically significant difference between the different age groups or between boys and girls. Patients with head and neck skin lesions showed problems with personal relationships and treatment (p<0.05). Conclusion: AD affects the QOL of children and adolescents with AD as the severity of the disease increases. In managing AD patients, not only evaluating the clinical severity of the disease but also evaluating QOL is necessary, and emotional support could be helpful to increase the QOL of childhood and adolescent AD patients. (Korean J Dermatol 2011;49(5):415∼421)