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음곡(陰谷) 오수유(吳茱萸) 약침(藥鍼)이 난소적출(卵巢摘出) 생귀의 골다공증(骨多孔症) 미치는 영향(影響)
최성훈 ( Sung Hoon Choi ),이병렬 ( Byung Ryul Lee ),양기영 ( Gi Young Yang ),김재규 ( Jae Kue Kim ),서영석 ( Young Suk Seo ),임윤경 ( Yun Kyoung Yim ) 대한경락경혈학회 2010 Korean Journal of Acupuncture Vol.27 No.2
Objective: This study is aimed to evaluate the effects of Evodiae Fructus herbal-acupuncture (EF-HA) at KI10 on osteoporosis induced by ovariectomy in mice. Method: Mice underwent bilateral ovariectomy. After recovering, the ovariectomized (OVX) mice were treated by needle prick, saline injection, herbal acupuncture with Evodiae Fructus (EF-HA) at KI10 for 8 weeks. Result: 1. EF-HA at KI10 significantly inhibited the overgrowth of tibia in ovariectomized mice. 2. NP at KI10 significantly restored the tibial BMD (bone mineral density) in ovariectomized mice. 3. EF-HA at KI10 significantly restored the phosphorus and creatinine levels in ovariectomized mice serum. 4. EF-HA at KI10 significantly restored the tibial Ca and P levels in ovariectomized mice. 5. EF-HA at KI10 significantly reduced the tibial osteoclast-like cells in ovariectomized mice. 6. EF-HA at KI10 significantly inhibited the overgrowth of tibial GPL (growth plate length) in ovariectomized mice. Conclusion: EF-HA at KI10 has protective and therapeutic effect for osteoporosis in ovariectomized mice. Thus, it is suggested that EF-HA can be an useful therapeutics in clinical field after further researches.
양릉천(陽陵泉) 우슬(牛膝) 약침이 흰쥐의 고지혈증에 미치는 영향
최준수 ( Joon Soo Choi ),임윤경 ( Yun Kyung Yim ),이병렬 ( Byung Ryul Lee ),양기영 ( Gi Young Yang ),김재규 ( Jae Kue Kim ) 대한경락경혈학회 2010 Korean Journal of Acupuncture Vol.27 No.3
Objective & Methods: The purpose of this study is to observe the effects of herbal- acupuncture with Achyranthis Radix(AR-HA) at GB34(Yangleungchean) on hyperlipidemia in rats. The author performed several experimental items to analyze the levels of various components and enzymes in serum and liver, as well as the histological changes of liver and aorta. Results: 1. Achyranthis Radix herbal acupuncture solution increased DPPH radical scavenging activity and HMG-CoA reductase inhibition rate in rat liver cells. 2. AR-HA at GB34 decreased the level of serum total cholesterol, and increased the ratios of HDL-cholesterol to total cholesterol, phospholipid to total cholesterol in hyperlipidemic rat. 3. AR-HA at GB34 decreased the hepatic HMG-CoA reductase activity in hyperlipidemic rat. 4. AR-HA at GB34 increased the hepatic GSH level in hyperlipidemic rat. Conclusion: From the above results, it is suggested that AR-HA at GB34 has a therapeutic effect on hyperlipidemia.