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유희준 ( Hee Joon Yu ),양홍윤 ( Hong Yoon Yang ),김윤석 ( Yun Suck Kim ),은철 ( Chul Eun ),장세진 ( Se Jin Jang ),박용욱 ( Yong Wook Park ) 대한피부과학회 1998 대한피부과학회지 Vol.36 No.2
Trichoadenoma is a rare cutaneous tumor that was first described by Nikolowski in 1958. It usually occurs as a single tumor on the face and its size varies from 3 to 50mm in diameter. It may arise any time during adult life. This tumor is less mature than trichofolliculoma and more differentiated than trichoepithelioma, and it is considered as a benign tumor with differentiation toward the infundibular portion of the pilosebaceous canal. In this report, we describe a 61-year-old women who developed trichoadenoma on the left shoulder of 3 years duration. The lesion was asymptomatic and had grown slowly. Histopathological findings showed numurous horn cysts with central keratinous material and solid tumor islands reaching to the deep dermis. Immunohistochemical studies showed negative findings for eccrine differentiation. (Korean J Dermatol 1998;36(2) . 372-375)
유희준 ( Hee Joon Yu ),이창우 ( Chang Woo Lee ),양홍윤 ( Hong Yun Yang ),김정수 ( Joung Soo Kim ),김윤석 ( Yun Suck Kim ) 대한피부과학회 1998 대한피부과학회지 Vol.36 No.5
Most insects including the honeybee cause erythema and edema at the site of a sting in non-allergic individuals. This reaction usually resolves within a few days. However, in certain cases, the persistence of inciting materials in the cutaneous tissue may promote a local inflammatory foreign body reaction. Localized nodular lesions were seen in our two patients and erythemstous patches were present in one patient due to rarely encountered complications induced by retained sting materials. In these cases histopathology showed multiple foci of foreign body granuloma containing yellow refraetile material in the center surrounded by histiocytes and foreign body giant cells. The granulomatous skin lesions in these patients were treated with intralesional injections of triamcinolone acetonide and partial excisions of the nodular masses were performed (Korean J Dermatol 1998;36(5): 914-917)
균상 식육종에서 발생한 Ki-1 양성 대형세포 림프종 1예
노영석,김윤석,박찬금 대한피부과학회 1999 大韓皮膚科學會誌 Vol.37 No.5
Mycosis fungoides(MF) is a cutaneous T-cell lymphoma of low-grade malignancy characterized by the proliferation of small to medium-sized cerebriform lymphoid cells confined to the skin. It usually shows favorable prognosis, but morphologic transformation occurs in some cases and is often associated with a more aggressive clinical course. Herein we report a case of Ki-1 positive large cell lyrnphoma (Ki-1 LCL) which developed in the plaque stage of mycosis fungoides. Although the lesions responded well to low-dose methotrexate therapy and there was no evidence of local or systemic recurrence until now, continuous follow-up is needed because the prognosis of transformed MF is known to be poor compared with primary cutaneous Ki-1 LCL. We also discussed the differential diagnosis of primary cutaneous Ki-1 positive lymphoproliferative disorders.