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수학적 모델을 이용한 신종인플루엔자 환자 예측 및 대응 전략 평가
서민아,이지현,지혜진,김영근,강대용,허남욱,하경화,이동한,김창수,Suh, Min-A,Lee, Jee-Hyun,Chi, Hye-Jin,Kim, Young-Keun,Kang, Dae-Yong,Hur, Nam-Wook,Ha, Kyung-Hwa,Lee, Dong-Han,Kim, Chang-Soo 대한예방의학회 2010 예방의학회지 Vol.43 No.2
Objectives: The pandemic of novel influenza A (H1N1) virus has required decision-makers to act in the face of the substantial uncertainties. In this study, we evaluated the potential impact of the pandemic response strategies in the Republic of Korea using a mathematical model. Methods: We developed a deterministic model of a pandemic (H1N1) 2009 in a structured population using the demographic data from the Korean population and the epidemiological feature of the pandemic (H1N1) 2009. To estimate the parameter values for the deterministic model, we used the available data from the previous studies on pandemic influenza. The pandemic response strategies of the Republic of Korea for novel influenza A (H1N1) virus such as school closure, mass vaccination (70% of population in 30 days), and a policy for anti-viral drug (treatment or prophylaxis) were applied to the deterministic model. Results: The effect of two-week school closure on the attack rate was low regardless of the timing of the intervention. The earlier vaccination showed the effect of greater delays in reaching the peak of outbreaks. When it was no vaccination, vaccination at initiation of outbreak, vaccination 90 days after the initiation of outbreak and vaccination at the epidemic peak point, the total number of clinical cases for 400 days were 20.8 million, 4.4 million, 4.7 million and 12.6 million, respectively. The pandemic response strategies of the Republic of Korea delayed the peak of outbreaks (about 40 days) and decreased the number of cumulative clinical cases (8 million). Conclusions: Rapid vaccination was the most important factor to control the spread of pandemic influenza, and the response strategies of the Republic of Korea were shown to delay the spread of pandemic influenza in this deterministic model.
하경진,박홍수,배장순,김영근 ( Kyung Jin Ha,Hong Soo Park,Jang Soon Bae,Young Keun Kim ) 한국유화학회 1997 한국응용과학기술학회지 Vol.14 No.3
Low foaming acidic degreasing agent(LFADAs) were prepared by blending sorbitol, n-octanoic acid, MJU-100A, Tetronix T-701, Na-dioctyl sulfosuccinate, Demol C, and phosphoric acid. The physical properties of LFADAs tested with aluminum specimen showed the following results ; when 3wt% LFADA-6 was performed at 70℃, the degreasing rate was 95% which is comparitively good, and the percentage of etching was 0.275% which was found to be less than that of commercialized product. When 20wt% of LFADA-6 was added at 65℃, the percentage of derusting was 92% and the good defoaming effect proved by following low foaming power tests respectively : Ross and Miles, and Ross and Clark methods.