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두피 지루피부염에서 Home-use Light Emitting Diode (LED)의 치료효과: 예비연구
김승면,이승철,원영호,이지범 대한의진균학회 2014 대한의진균학회지 Vol.19 No.2
Background: Seborrheic dermatitis (SD) is a chronic, relapsing inflammatory disease, mainly affectingthe scalp and face. The pathogenesis of SD has been not fully understood yet, but may be related to theskin colonization of Malassezia species, lipophilic yeasts. Phototherapy with light emitting diode (LED)device has been become a new therapeutic modality for some skin diseases such as acne. Objective: To evaluate effectiveness and safety of phototherapy with home-use LED in the treatmentof patients with SD of the scalp. Methods: Eight patients with mild-to-moderate SD of the scalp participated. The patients used ahome-use LED device combined 395 nm blue light with 660 nm red light for 6~7 min twice daily for 8weeks. Patients' assessments were made by clinical findings including erythema (0~15), scales (0~15),itching (0~10), and lesional extent (0~15). And clinical photographs were taken at 0, 2, 4 and 8 weeks,respectively. Results: At 8 weeks after LED treatment, erythema (7.75 to 5.13, p=0.018), scales (7.38 to 4.13,p=0.017), itching (6 to 3, p=0.011) and lesional extent (8.25 to 5.25, p=0.017) were significantlydecreased, respectively. Satisfactory scores were also relatively high (mean 8.13 of 10). No severeadverse reaction was reported, excepting hair dryness (n=1) and brief stinging sense (n=1). Conclusion: Home-use LED was effective and safe in the treatment of SD of the scalp. These resultssuggest the LED device might be an adjuvant therapeutic tool in the treatment of Malassezia speciesassociated diseases such as dandruff and SD. Further long-term and large-scale studies are required toassess the efficacy and safety of home-use LED.
김승면 ( Seung Myun Kim ),이지범 ( Jee Bum Lee ),이승철 ( Seung Chul Lee ),원영호 ( Young Ho Won ),윤숙정 ( Sook Jung Yun ),김성진 ( Seong Jin Kim ) 대한피부과학회 2014 대한피부과학회지 Vol.52 No.8
Eccrine porocarcinoma is a rare cutaneous neoplasm arising from the eccrine sweat duct. It may arise de novo or evolve from a pre-existing poroma or hidroacanthoma simplex. The pigmented variant of porocarcinoma is very rare, and its heavy pigmentation can lead to misdiagnosis of seborrheic keratosis or melanoma. An 82-year-old male patient presented with a painful, brown-to-black colored plaque measuring 4×4.5 cm with a central pedunculated nodule that measured 2.5×2 cm on his right posterior thigh. A small, pigmented papule had developed 10 years prior and had gradually increased in size. Histopathologic examination of the nodule revealed lobulated tumor islands composed of atypical basaloid cells in the periphery, eosinophilic squamous cells in the center, and pigmented dendritic cells scattered throughout nests of the tumor. Carcinoembryonic antigen and epithelial membrane antigen were expressed in the tumor cells and the dendritic cells stained positive for S-100 and HMB45. Histopathologic findings from the plaque showed many pigmented nests embedded within the epidermis that were composed of small, polygonal, pigmented basaloid cells. Pigmented eccrine porocarcinoma arising from pigmented hidroacanthoma simplex was diagnosed clinically and histopathologically. The tumor was completely excised. We report a case of pigmented porocarcinoma, which should be included among clinically important differential diagnoses apart from melanoma. (Korean J Dermatol 2014;52(8):574∼579)
소음저감을 위한 전기자동차용 PTC히터의 소자배열에 따른 열변형 해석
김승면(Seung-Myeon Kim),전의식(Euy-Sik Jeon) 한국산학기술학회 2015 한국산학기술학회 학술대회 Vol.2015 No.1
본 논문은 전기자동차에 적용하는 PTC히터의 소음 저감을 위해 시뮬레이션을 통한 PTC소자의 배열에 따른 열변형을 관찰하고, 각 인자의 영향도를 분석하여 큰영향도를 갖는 인자를 확인하였다. 각 인자의 영향도를 분석하기 위하여 PTC소자의 간격, 소자간의 중첩범위, 소자의 세로길이, 소자의 가로길이를 인자로 하여 각 3수준의 실험계획표에 따른 열-구조 연성해석을 통하여 큰영향도를 갖는 인자을 확인하였다.