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신장 : 신증후군 환자에서 병발한 간문맥 혈전증 및 급성 췌장염 1예
김낙민 ( Nak Min Kim ),유지형 ( Ji Hyung Yoo ),성우경 ( Woo Kyung Sung ),윤수아 ( Su A Yun ),정진욱 ( Jin Uk Jeong ),신종호 ( Jong Ho Shin ),방기태 ( Ki Tae Bang ) 대한내과학회 2015 대한내과학회지 Vol.88 No.2
Nephrotic syndrome is characterized by hypercoagulability and thrombosis of the renal and deep veins. We describe a case of unusual thrombosis in the portal and superior mesenteric veins of a 41-year-old female, admitted for treatment of abdominal pain, who simultaneously presented with nephrotic syndrome and acute pancreatitis. Laboratory analysis revealed hypoalbuminemia, hyperlipidemia, and proteinuria. Abdominal computed tomography revealed acute pancreatitis, thrombosis at the portal and superior mesenteric veins, and ischemic changes in the colon and small intestines. Anticoagulation therapy was started immediately. Abdominal pain was subsequently reduced and the ischemic lesion disappeared. Warfarin use could not be terminated immediately. Empirical steroid therapy commenced without a kidney biopsy. Complete remission occurred after 4 weeks. Following warfarin cessation, a kidney biopsy was performed, confirming the diagnosis of minimal change disease. (Korean J Med 2015;88:212-217)
증례 : 신종플루 백신 접종 후 발생한 전신성 홍반성 루푸스 1예
조성민 ( Seong Min Jo ),신종호 ( Jong Ho Shin ),방기태 ( Ki Tae Bang ),정진욱 ( Jin Uk Jeong ),김낙민 ( Nak Min Kim ),최지욱 ( Ji Wook Choi ),김주헌 ( Ju Hun Kim ) 대한내과학회 2013 대한내과학회지 Vol.84 No.2
저자들은 기존 병력이 없던 17세 여자 환자가 신종플루 백신 접종 후 루푸스가 발생하여 치료 후 호전된 첫 증례를 경험하여 보고하는 바이다. The recent worldwide outbreak of H1N1 has led to the universal administration of H1N1 influenza vaccination, including in South Korea. Several complications have been reported with use of H1N1 influenza vaccine, but systemic lupus erythematosus (SLE) has not been reported as a complication until now. Here, we report a case of SLE occurrence after H1N1 influenza vaccination. A 17-year-old girl who had not been diagnosed with SLE was hospitalized with fever, myalgia, and arthralgia after H1N1 influenza vaccination. Laboratory tests revealed increased levels of antinuclear antibody and anti-ds-DNA antibody, and decreased levels of C3 and C4 as well as proteinuria. The pathological findings confirmed a diagnosis of lupus nephritis. The patient was treated with high-dose corticosteroid and hydroxychloroquine. This is the first report of SLE following H1N1 influenza vaccination in South Korea. (Korean J Med 2013;84:295-298)
유지형 ( Jihyung Yoo ),김낙민 ( Nak Min Kim ),성우경 ( Wookyung Sung ),명진철 ( Jin Cheol Myeong ),윤수아 ( Su A Yun ),이동규 ( Dong Kyu Lee ),임미경 ( Mi Kyoung Lim ),신동혁 ( Dong Hyuk Sheen ) 대한류마티스학회 2015 대한류마티스학회지 Vol.22 No.4
베체트병에서 말초 신경계 침범은 아주 드물게 보고되었다. 저자들은 베체트병 환자에서 갑작스러운 근육 위약감이 발생하여 진행하는 증상과 신경전도검사에서 확인된 길랑-바레 증후군을 진단하였고, 약물 치료 후 증상이 호전됨을 경험하여 문헌으로 보고하는 바이다. Behcet’s disease (BD) is a multi-systemic inflammatory disease of unknown origin that affects nearly all organs including the nervous system. Although the neurological involvement is less frequent than other major presentations, it is important because it can produce severe disabilities. Peripheral nervous system manifestations are relatively rare in BD. Although few cases of peripheral neuropathy or myopathy have been reported in BD, they are cases of multiple neuropathies, sensorimotor peripheral neuropathy, or neuropathy autonomic dysfunction. Guillain-Barre syndrome (GBS), also known as an acute inflammatory demyelinating polyneuropathy, is an acute demyelinating polyradiculopathy of uncertain etiology. No case of GBS associated with BD in Korea has been reported. Herein we report on a patient of BD who suffered from weakness of extremities and was diagnosed as GBS. (J Rheum Dis 2015;22:246-249)