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Zipeprol 남용환자에서 뇌 단일광자방출 전산화단층촬영술의 임상적 의의
김광원(Kwang Won Kim),최영길(Young Kil Choi),고은미(Eun Mi Koh),김덕윤(Deog Yoon Kim),조대옥(Dai Ok Cho),김재필(Jae Phil Kim),양현인(Hyung In Yang) 대한핵의학회 1993 핵의학 분자영상 Vol.27 No.1
N/A Drug abuse is widespread in worldwide and has been associated with neurologic complication. Zipeprol is one of drugs which been abused for psychological satisfaction in some adolescents. This agent is non-opioid antitussive agent, which is not legally considered as being capable of creating dependence or abuse liability at therapeutic serum levels. But it has been reported that acute or chronic overdose create neurologic complication such as convulsion as well as dependence. Recently we experienced six zipeprol abusers who admitted due to convulsion and variable neurologic symptoms. The aim of our study was to determine the role of Tc-99m- HMPAO brain SPECT in those patients. EEG and brain CT showed no abnormal finding, but brain SPECT showed focal or multiple perfusion abnormalities in frontal, parietal, occipital cortex, basal ganglia, thalamus and especially at temporal cortex. These results suggest that brain SPECT may be a useful diagnostic tool to evaluate the cerebral dysfunction indused by zipeprol abuse.
정상 관동맥 조영상을 갖는 급성 심근경색증 환자의 임상적 특징 및 99mTc - MIBI 심근 SPECT 소견
김광원(Kwang Won Kim),김덕윤(Deog Yoon Kim),박명재(Myung Jae Park),최태열(Tae Youl Choi),강홍선(Heung Sun Kang),조정휘(Chung Whee Choue),김권삼(Kwon Sam Kim),김명식(Myung Shick Kim),송정상(Jung Sang Song),배종화(Jong Hoa Bae) 대한핵의학회 1993 핵의학 분자영상 Vol.27 No.1
N/A Among 64 patients with acute myocardial infarction who underwent coronary angiogrphy, 7 patients (10.9%)showed normal coronary artery. Six patients were men and 1 patient was female. The mean age of patients were 31.1±3.9 years. Among the risk factors of coronary heart disease, smoking was most probable factor in patients with acute myocardial infarction with normal coronary angiography. Tc-99m-MIBI heart SPECT performed 5 of 7 patients and showed that it could be used in diagnosis, localization, extent of infarct area in patients with acute myocardial infarction with normal coronary angiography. But follow up Tc-99m-MIBI heart SPECT study will be needed to define the ability of myocardial viability in this patients.
김광원(Kwang Won Kim),최영길(Young Kil Choi),고은미(Eun Mi Koh),김덕윤(Deog Yoon Kim),김병호(Byung Ho Kim),장영운(Young Woon Chang),장린(Rin Chang),김용봉(Yong Bong Kim) 대한핵의학회 1990 핵의학 분자영상 Vol.24 No.2
N/A Scintigraphic measurement of gastric emptying time has been reported to be influenced by the variation in depth of radionuclide within the stomach. In order to determine the effect of tissue attenuation in the measurement of gastric emptying time, 15 gastric emptying studies were performed with Tc-99m labeled egg sandwiches. Single anterior detector method overestimated the T1/2 by an average of 13% than geometric mean method and the range of overestimation was wide (from -13% to +32%). Therefore, to evaluate the gastric empthying time accurately, methods of attenuation correction are needed.
김광원(Kwang Won Kim),최인선(In Seon S . Choi),박석채(Seog Chea Park),장안수(Ahn Soo Jang),임호(Ho Lim) 대한내과학회 1999 대한내과학회지 Vol.57 No.1
N/A Researches on the characteristics of fatality-prone asthmatics have been performed in western countries, but there are few reports in this field in Korea. The purposes of this study were to clarify the magnitude of the problem and to identify the risk factors of near-fatal asthma(NFA). Methods : The records of patients admitted due to asthma attack were analyzed retrospectively. Results :1) The subjects had NFA in 50.6% and PaCO2 > 45mmHg in 22.9%. Five(11.1%) among NFA patients and 3 out of 19(15.8%) subjects with PaCO2 > 45mmHg required mechanical ventilation. 2) There were no significant differences between NFA and non-NFA in age, sex, resident place, academic career, familial and personal history of atopic diseases, serum total IgE level, positive skin prick test to house dust mites, accompanying allergic rhinitis and aspirin intolerance, emphysema on chest high resolution computerized tomogram, dyspnea perception, previous asthma education, regular OPD follow-up, and use of antiinflammatory drugs. 3) However, cigarette smoking(62.2% vs 38.6%), accompanying paranasal sinusitis(66.7% vs 45.3%), chronic asthma severity(severe persistent: 55.5% vs 29.5%), hospitalization frequency(2.93 vs 1.58), and duration of recent asthma exacerbation(6.6 vs 18.8 days) in NFA were significantly different from those in non-NFA.4) The relative risk for NFA was high in patients with history of hospitalization > 3, severe persistent asthma, exacerbation period < 3 days, smoking, or sinusitis in the order of frequency. Conclusion : Near-fatal asthma is a prevalent problem in clinical practice and asthma admission history, severe persistent asthma, short exacerbation period < 3 days, smoking, and paranasal sinusitis are the risk factors warning near-fatal asthma attack in advance.