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비만유도 흰쥐에서 반복적 절식과 운동부하가 골격근내 세포사멸 및 당수송체에 미치는 영향
정석호(Jung, Suk-Ho),김기훈(Kim, Ki-Hoon),서효빈(Seo, Hyo-Bin),김도헌(Kim, Do-Hyeon),권천달(Kwon, Cheon-Dal),전병덕(Jeon, Byung-Duk),최승식(Choi, Seung-Sig),노미라(Roh, Mi-Ra),권태동(Kwon, Tae-Dong) 한국체육과학회 2022 한국체육과학회지 Vol.31 No.5
The purpose of this study is to rely on an extremely limited diet weight loss is a heavy negative effect on intracellular lipid metabolism and reduced insulin secretion induced by inhibition of intracellular homeostasis was thought to be a factor. For therefore investigate the physiological effects of exercise was conducted. Twenty-two Sparague Dawley rats were divided into 4 groups as follows: high fat diet group(HF, n=8), high fat diet with repeated fasting and refeeding group (HFFR, n=8), repeated fasting and refeeding and exercise after high fat diet group(HFFR+EX, n=8) and pair feding to HFFR group (HFFR+PF, n=8). Diet-induced obesity was fed a high-fat for 8 weeks, and obesity intervention was drived by treadmill running exercise program or food intake restriction. As a result, through repeated food restriction were decreased body weight, body fat reduction and improvement blood lipid profiles. And when combined exercise training was confirmed this trend more pronounced(p<.05). Furthermore, the expression of GLUT4 expression in skeletal muscle decreases due to restricted movement, but it was confirmed to be increased through exercise training. Expression of apoptosis-related CHOP mRNA were combined exercise and dietary restriction significantly decreased. In conclusion, the results of this study, including obesity, diabetes and other metabolic syndrome disorders in a course of treatment being carried out mainly in the dietary restriction and exercise programs to the specific direction is expected to be present.
수영운동과 솔잎분말 첨가식이 섭취 흰쥐의 L-FABP, CPT-1의 발현량과 항비만에 미치는 영향
신동아(Shin, Dong-A),서효빈(Seo, Hyo-Bin),정석호(Jung, Suk-Ho),남주옥(Nam, Ju-Ock),권태동(Kwon, Tae-Dong) 한국체육과학회 2020 한국체육과학회지 Vol.29 No.2
The purpose of this study is to examine how a pine needle powder-added diet and swimming exercise influence fat metabolism and inflammatory cytokine in a high cholesterol diet. 42 male Sprague-Dawley rats were made to practice a pine needle powder-added diet and swimming exercise along with a high cholesterol diet for six weeks. The HCE and the HCPEN showed significant decrease in their weight in the sixth week, and according to the results of dispersion analysis, it was found to be significant in the group × week. About the change of intake in the diet, the HC and HCE were found to be significant high, and according to the results of dispersion analysis, it was not significant in the group × week and regarding diet efficiency, the EX, HCPN, and HCPNE were found to be significant high. About the change of fat, abdominal fat was significantly high in the HC and HCPN, and testicle fat was significantly high in the HC, and mesenteric fat did not indicate significant difference. According to the results of fat metabolism, regarding the change of L-FABP expression in liver tissues, the CON and EX indicated a significantly higher expression compared to each of the other groups, and CPT-1 expression did not show significant difference. herefore, according to the results of this study, reduction in weight, body fat, and blood lipids led by the exercise and pine needle powder-added diet activated AMPK and the acceleration of PPAR-γ, FABP, and CPT-1 as the result of the exercise, and this led to the regulation of fat metabolism. Moreover, regarding the results of pine needle powder intake in the diet, pharmacological compounds contained in pine needles such as phenols and flavonoids are thought to influence fat metabolism positively. This author deems that the results of this study provide foundational material regarding the influence of exercise and pine needle powder-added diet’s complex treatment on anti-obesity improvements.