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구순모,이건수 慶北大學校 醫科大學 1983 慶北醫大誌 Vol.24 No.2
1972년 1월부터 1982년 12월까지 만 11년간 경북의대 부속병원 소아과에 급성중독으로 입원된 93명에 대해 임상적 관찰을 행하여 다음과 같은 성적을 얻었다. 성별분포는 총 93명중 남아 57명, 여아 36명으로 남여비는 1.6:1로 남아가 많았으며 연령별분포는 1-5세군이 54.8%로 가장 높았다. 중독물질은 살충제가 21.5%로 가장 많았고, 그외 일산화탄소 20.4%, 살충제 18.3%, DDS 12.9% 등의 순위였고 살충제, 살서제 등은 주로 농촌지역에, 일산화탄소 및 DDS중독은 도시지방에 많았다. 중독의 동기는 90.3%가 우발사고였고 치료도중 중독예가 5.4%, 자살의 목적이 4.3%였다. 환아의 경과는 총93명중 불완전회복 14명으로 15.7%, 사망이 3명으로 9.6%를 보였으며, 일산화찬소, 살충제 및 살서제의 사망율은 각각 10%, 10.5%, 11.8%였고 DDS의 경우는 사망이 1명도 없었다. A clinical study was done on 93 children with acute poisoning, who had been admitted to the Pediatric Department of Kyungpook National University Hospital during 11 years period, from 1972 to 1982, and following results were obtained. Male to female ratio was 1.6:1, and 1-5 years of age group was involved most frequently, comprising 54.8%. Out of 24 causative substances, pesticide was the most frequent cause of poisoning(21.5%), followed by CO gas(20.4%), rodenticide(18.3%), DDS(12.9%), and others. Poisoning with pesticide and rodenticide occurred more often in rural area than urban; whereas poisoning with CO gas and DDS in urban. The most frequent motive of poisoning was "by accident" in 90.3% followed by "therapeutic purpose" in 5.4% and "suicidal purpose" in 4.3%. Four out of five cases poisoned by "therapeutic purpose" occurred in children under five years of age and three out of four cases by "suicidal purpose" in children over 11 years of age. Total mortality rate was 9.6%, and those of poisoning due to CO gas, pesticide, and rodenticide were 10.0%, 10.5%, and 11.8% respectively. No death occurred ies with DDS poisoning.
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1982년 경북지방 우량아 선발대회에 참가한 영유아의 성장발육상
이원석,구순모,강덕식,이건수 慶北大學校 醫科大學 1982 慶北醫大誌 Vol.23 No.2
1982년 경북지방 우량아 선발대회에 참가한 영유아(9-24개월) 442명을 대상으로 이들의 각종 신체계측치 및 혈청단백량, 비타민 D 결핍상황을 살펴본 결과 다음과 같은 결론을 얻었다. (1) 체중에 있어서 한국표준치 및 일본평균치와 비교하여 남녀 모두 2.11∼3.19kg 1.25-2.25kg 우위에 있었고 신장 역시 4.29-6.75cm 및 2.46-2.73cm 우위에 있었으며 흉위 및 두위에 있어서도 각 0.75-4.48cm, 1.33-4.04cm 및 6.54-2.17cm, 0.1-1.06cm 씩 우위임이 측정되었다. (2) 피부두께 측정치에서 Triceps skin fold thickness가 홍등의 계측치에 비해 남아는 0.40-1.48mm, 여아는 1.41-1.93mm, scapular thickness에서는 남아 2.29-2.44mm, 여아가 2.35-2.83mm우위에 있었다. (3) 상완둘레는 홍등의 계측치보다 남아 2.53-2.77cm, 여아 2.19-2.43cm 우위에 있었다. (4) Hand refractometer를 사용하여 측정한 혈청단백량은 남아평균 7.00gm% 여아 7.08gm%로서 연령별 차이는 없었다. (5) kaup지수 20이상은 남아에서 7.8% 여아 6.3%로 나타났다 (6) 수유방법에서는 모유영양이 가장 많아 50.2%였으며 다음이 혼합, 인공영양의 순서였다. (7) 이유시기는 56.6%가 4-6개월에 시작하여 1년이내에 대부분(98.8%)이 시작한 것으로 나타났다. (8) 헤마토크맅치가 33미만인 빈혈환아는 4.75%였고 약 1/3에서 철분투여가 이루어졌으며 빈혈은 철분투여군에서 3.4%, 비투여군에서 5.4% 발생하였다. (9) 약 1/4에서 비타민 D가 투여되었으며 D 부족증상은 12.7%에서 발견되었고 이들의 대부분이 (80%) 이전에 비타민 D 공급을 받지 못했으며 투여군에서 10%, 비투여군에서 13.6% 나타났다. (10) 본 조사군에서는 과거 5년간에 비해 성장발육(체중, 신장, 흉위, 두위, 상완둘레, 피부두께은 큰 차이가 없으나 비만정도, 빈혈, 비타민 D 부족증상은 많은 감소를 보였다. Authors have conducted a study on 442 infants participated in Kyungpook regional wellbaby contest, held in 1982. After through investigation of several parameters including physical growth (body weight, height, chest and head circumferences), nutritional status (Kaup index, serum protein, hematocrit and signs of vitamin C deficiency), and feeding history, along with comparing this with data obtaind from past 5 years (1976-1980), the following results were obtained. Comparing their body weight, height, chest and head circumferences with Korean children's growth standard(K.S.) and Japanese children's growth standard(J.S.), their body weight were superior to those of K.S(2.11-3.19kg) and J.S(1.25-2.25kg), their height superior to those of K.S(4.29-6.75cm) and J.S(2.46-2.73cm) but no remarkable diference between these data and those obtained from past 5 years. Triceps skin fold thickness and scapular thickness were superior to those of Hong(0.4-1.93mm,2.29-2.83mm), the arm circumference were superior to those of Hong(2.19-2.77mm), too. But no remarkable difference between these data and those obtained from past 5 years were found. Total mean serum protein was 7.0gm% in male infants and 7.08gm% in female infants. Kaup index was over 20 in 7.8% in male infants and 6.3% in female infants. Compared to past 5 years, obesity was found less frequently. Breast milk feeding was the most common form of the infant feeding comparing 50.2%, followed by mixed feeding 29.8%, and bottle feeding in 20%. Weaning was started between 4-6 months of age in 56.6% of infants and the vast majority within 12 months of age (98.9%) About 5% of those infants showed anemia, using the cirteria of anemia as being hematocrit less than 33%. They were found in 3.4% of infants with iron-supplemented group, and 5.4% of infants without iron supplementation. In 12.7% of the infants, there were signs of the vitamin D deficiency including Harrison's groove, rachitic rosary, and pigeon chest. They were found in 10% of infants with vitamin D supplementation and 13.6% of infants without supplementation. Compared to past 5 years, anemia and vitamin D deficiency were found less frequently.
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소아에서의 각종 신질환과 B형간염 바이러스감염과의 관계
김용진,이상범,김연옥,구자훈,구순모 대한신장학회 1984 Kidney Research and Clinical Practice Vol.3 No.2
A clinical study was conducted on 273 children with various renal diseases, who had been admi- tted to the pediatric ward of KNU hospital from November 1980 to February 1984. Incidence of HBsAg positivity was 9. 5 in the renal groups compared to 5, Q .g in the controls, and among th various renal diseases, primary glomerulonephritides causing nephrotic syndrome showed the highest rate of 20.4%.(ll out of 54 cases; p$lt;0. 01). Among the biopsy-proven primarv glomerulonephritides, the highest rate of HBsAg positivity was seen in MGN with 50.0,.(4 out of 8 cases; p$lt;0.05). HBeAg positivity in patients with HBs antigenemia also showed the highest rate in MGN groups, occuring in 3 out of 4 cases. Tissue staining of HBsAg utilizing PAP method (Dako Co. USA) on the biopsy-specimens of renal tissue from 13 children with HBs antigenemia(11 cases with primary nephrotic syndrome, 2 with HSP nephritis) showed negative staining in all of the specimens. In summary, our data would suggest that there is a strong correlation between hepatitis B viral infection and the primary glomerulonephritides, especially membranous nephropathy. Futhermore, it would indicate that HBeAg might play more prominent role than HBsAg in the pathogenesis of membranous nephropathy.
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