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- 저자 : 곽현진(Hyun Jun Kwak) (검색결과 1 건)
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최창균(Chang Keun Choi),윤광식(Kwang Sik Yoon),이승복(Seung Bock Lee),정안철(An Chul Jeong),안병진(Byung Jun Ahn),문도호(Do Ho Moon),도승경(Sung Kyoung Doh),곽현진(Hyun Jun Kwak),김용훈(Yong Hoon Kim),이홍순(Hong Soon Lee),유수웅(Soo 대한내과학회 1998 대한내과학회지 Vol.55 No.1
N/A Objective : Pattern with essential hypertension g ally shows the same circadian pattern as the normothensive person with a night-time reduction or DIP in blood pressure in sleep. The definition of Dipper and Non-dipper are assigned according to arbitrary criteria e.g. a night time average blood pressure which is at least 10% less than the average daytime blood pressure. Prospective evidence that the absence of an overnight dip is a strong adverse prognostic. indicator for target organ damage .Thus we investigate circardian rhythm of blood pressure, related target organ damage, its frequency & drug in hypertensive subjects. Method: 24hr ambulatory blood pressure monitoring, history taking, physical examination, fundoscopy, ECG, chest X ray, dipstick urinanlysis, serum creatinine level are performed in essential hypertensive subjects. Exclusion criteria are duration of hypertension over 5 years, DM, renovascular hypertension & heart failure. Results : Total 42 patients performed study.17 subjects classify dipper group,25 subjects classify non-dipper group. Between dipper 8c non-dipper group shows no significantly difference at stroke history, C/T ratio over 0.5 in chest X-ray, left ventrcular hypertrophy in ECG,ST-T change in ECG, proteinuria & serum creatinine level. Non-dipper group shows significantly difference to dipper group in frequency of hypertensive retinopathy and number of combined drug used subjects. Conclusion Number of hypertensive retinopathy is significantly frequency in non-dipper group. Hypertensive retinopathy is atherosclerotic complication, thus we predict other target organ damage, therefore non-dipper type circardian rhythm of blood pressure is adverse prognostic factor for target organ damage of hypertensive subjects.
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