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      • KCI등재후보

        고관절 이형성을 지닌 Retriever에서 대퇴골두 절단술의 적용

        고희곤,정순욱,김준영,정만복,한현정,김지선 한국임상수의학회 2003 한국임상수의학회지 Vol.20 No.1

        This study was performed to evaluate the postoperative healing process according to lameness degree, swelling, and muscle atrophy after femoral head and neck ostectomy on Retriever dogs with hip dysplasia and hindleg lameness. Femoral head and neck ostectomy (FHO) was performed for the repair of hip dysplasia in 4 Retriever dogs (5 hips) referred in veterinary medical teaching hospital of college of veterinary medicine, Konkuk University. Age (Mean±SD) of patients was 10.3±3.0 months (range, 7 to 16 months) and body weight (Mean± SD) was 28.2±3.4 kg (range, 25 to 34kg). After FHO, all cases are treated with carprofen (2.2mg/kg, PO bid, tapering at interval 1-2 weeks) and physical therapy including passive range-of-motion exercises. In all cases, lameness degree was showed V at the next day after surgery, IV at 5 to 7 days, II-III at 30 to 35 days, II at 60 days, and I at 105 to 114 days. These results suggested that femoral head and neck ostectomy was able to be performed on large breed dogs with hip dysplasia and hindleg lameness.

      • 선형성을 개선한 저전압 CMOS RF 주파수 변환기 설계

        고희곤,김영석 충북대학교 컴퓨터정보통신 연구소 2003 컴퓨터정보통신연구 Vol.11 No.2

        본 논문은 선형성을 개선한 900MHz 저전압 CMOS 하향 주파수변환기를 제안하였고 회로 모의실험에 의하여 확인 하였다. 선형성 개선을 위하여 Class AB 트랜스컨덕터단을 사용하였고, RF 단과 LO 스위칭단을 캐패시터로 커플링시켜 저전압으로 동작 하게하였다. 1.0 GHz의 LO 신호를 가지고 3.0 V에서 동작하는 제안된 주파수 변환기는 회로 모의실험을 하여 선형성을 나타내는 ⅡP3는 4.8dBm, 변환이득은 0.6dB를 얻었다. 제안된 주파수 변환기는 길버트 주파수 변환기와 비교하여 선형성과 변환이득에서 개선됨을 보았다. 설계한 주파수 변환기는 RF 송수신기 시스템 등에서 활용될 것으로 기대된다. In this paper, the 900MHz low-voltage CMOS downconversion mixer with high linearity has been proposed and confirmed by circuit simulations. The class AB transconductor stage is used for high-linearity and capacitively coupled with LO switching stage for low-voltage applications. Circuit simulations show that the proposed mixer operating at 3.0V with 1.0GHz LO signal has ⅡP3 of 4.8dBm and conversion gain of 0.6dB. The linearity and conversion gain of the proposed mixer is much improved compared to that of the conventional Gilbert mixer. The proposed mixer with CMOS technology is used to be integrated into the one-chip RF transceiver system.

      • KCI등재후보

        Surgical Correction of Peritoneopericardial Diaphragmatic Hernia with Hepatic Necrosis in a Himalayan Cat

        김준영,정순욱,최보연,고희곤,윤헌영,정만복,한현정,황민,노병국 한국임상수의학회 2004 한국임상수의학회지 Vol.21 No.1

        A five months old, female Himalayan cat was referred to the Veterinary Medical Teaching Hospital at Konkuk University, because of suspecting peritoneopericardial diaphragmatic hernia (PPDH). After consecutive examination, the patient was diagnosed as PPDH and hepatic dysfunction. In spite of medical therapy for a month, the serum chemistry profiles for liver enzymes (aspartate transferase: 469 U/L, alanine transferase: above analysis, gamma-glutamyl transferase: above analysis) did not decrease to the normal range. In operation, some of liver was necrotized and was adhesive to diaphragm, these were gently dissected from thoracic structures, and resected. After debriding, the edges of the defect of diaphragm were closed with a simple continuous suture pattern. One month after operation, the cat had normal condition, recovery was uncomplicated, and the serum chemistry profiles for liver enzymes decrease to the normal range. 5년령의 암컷 히말라얀 고양이가 복막심낭횡경막 허니아가 의심되어서 건국대학교 수의과대학 부속 동물병원에 내원하였다. 일련의 검사를 실시한 후 환자는 복막심낭횡경막 허니아와 간기능 부전이 확진되었다. 그 후 한 달간의 약물치료에도 불구하고, 혈청화학검사에서 간효소 (aspartate transferase, alanine transferase, gamma-glutamyl transferase) 수치는 정상범위로 내려 가지 않았다. 이환자는 수술중에 간 일부가 횡경막에 유착되어서 괴사가 일어난 것이 발견 되었고, 유착되고 괴사된 간 조직은 횡경막에서 조심스럽게 분리하여 절제하였다. 횡경막은 괴사된 부분을 잘 정리하고 난 뒤에 손상된 횡경막 부분을 simple continuous suture pattern으로 봉합하였다. 수술 후 한 달 뒤 환축은 정상적인 상태를 보였고 다른 복합증 없이 회복되었다. 그리고 혈청화학 수치 중 간효소 수치도 정상 범위로 떨어졌다.

      • KCI등재

        Effects of Proanthocyanidin-rich Extract from Pinus radiata Bark on Immune Responses of Broiler Chickens

        박인재,차세연,강민,소양섭,고희곤,손영호,문성필,류경선,장형관 한국가금학회 2010 韓國家禽學會誌 Vol.37 No.4

        We evaluated the immunomodulatory effects of proanthocyanidin-rich extract (PAE) from Pinus radiata bark in broiler. Proliferation of peripheral blood mononuclear cells and thymocytes was significantly enhanced in 2.5, 5, 10 mg/kg PAE-treated broiler chickens. Proliferation of splenocytes was significantly enhanced in 1.25, 2.5, 5, 10 mg/kg PAE-treated broiler chickens. These effects were markedly enhanced by the presence of LPS, which acts on B cells responsible for humoral immunity, and Con A, which acts directly on T cells involved in cell mediated immunity. PAE significantly promoted the expression of interleukin-18 and interleukin-1β. Thus, PAE from P. radiata possesses immunomodulatory effects in broiler chickens.

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