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- 저자 : 고병용 ( Byoung Yong Koh ) (검색결과 5 건)
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광노화 병변의 유병률 조사 및 단일성과 다발성 광선각화증 환자들의 특성 비교: 환자 61명에 대한 후향적 연구
고병용 ( Byoung Yong Koh ),명기범 ( Ki Bum Myung ),한형진 ( Hyung Jin Hahn ),정승현 ( Seung Hyun Cheong ) 대한피부과학회 2017 大韓皮膚科學會誌 Vol.55 No.9
Background: Photoaged skin is characterized by actinic skin lesions such as wrinkling, elastosis, and premalignant and malignant lesions. Actinic keratosis (AK) is one of the most common precancerous lesions, and multiple actinic keratosis lesions are one of the risk factors for skin cancer. Few studies have investigated the prevalences of actinic skin lesions and compared the characteristics of the lesions and the patients with sinle and multiple AK lesions. Objective: The aim of this study was to evaluate the prevalences of actinic skin lesions and to compare characteristics between single and multiple lesions in Korean patients with AK. Methods: We retrospectively reviewed the medical records and biopsy specimens of 61 patients. Results: Frequencies of deep wrinkle, solar elastosis, cutis rhomboidalis nuchae, and senile purpura were higher in the multiple lesions group. The ratio of males to females was 1:3.43 and the mean age was 79 years in the multiple lesions group, both of which were higher than those in the single lesion group (1:1.14, 72 years). The mean duration was longer in the multiple lesions group. Sun protective behavior was more frequent in the single lesion group, and the occupation of farmer was more common in the multiple lesions group. There was no statistically significant clinicopathological difference between the two groups. Conclusion: This study may improve our understanding of the characteristics of actinic keratosis with both single and multiple lesions. (Korean J Dermatol 2017;55(9):580∼587)
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고병용 ( Byoung Yong Koh ),권은선 ( Eun Sun Kwon ),이경근 ( Kyung Geun Lee ),명기범 ( Ki Bum Myung ),정승현 ( Seung Hyun Cheong ) 대한피부과학회 2017 大韓皮膚科學會誌 Vol.55 No.10
A patient with nevus sebaceous showing linear or wide distribution can present with a triad of nevus sebaceous, seizures, and mental retardation. Most of those cases are classified as sebaceous nevus syndrome. Ophthalmological, skeletal, and other abnormalities may also be present. A male weighing 3,580 g was born at the gestational age of 38 weeks after a normal pregnancy. He was referred to the dermatologic department on the first day of life. He presented with yellow-orange and verrucous plaques on both sides of the temporal areas, face, neck, upper and lower extremities, and trunk. Skin biopsy specimens were taken from the scalp and right lower leg. Histologically, both specimens showed sebaceous gland hyperplasia, absence of mature hair follicles, infundibular cystic structures, and apocrine glands. Brain magnetic resonance imaging, transthoracic echocardiography, abdomen ultrasonography, and routine laboratory investigations were performed and showed nonspecific findings. The patient did not show seizure activity at 19 days of observation, and he is now on close observation. We herein report a very rare case of systematized nevus sebaceous presenting at birth. (Korean J Dermatol 2017;55(10):694∼697)
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이경근 ( Kyoung Geun Lee ),고병용 ( Byoung Yong Koh ),권은선 ( Eun Sun Kwon ),명기범 ( Ki Bum Myung ),권미혜 ( Mi Hye Kwon ),정승현 ( Seung Hyun Cheong ) 대한피부과학회 2017 大韓皮膚科學會誌 Vol.55 No.5
Acute cutaneous lupus erythematosus (ACLE) on the face is a usual pattern of presentation. However, it can rarely present with a generalized distribution. A hyperacute form of ACLE can mimic Stevens-Johnson syndrome (SJS) and toxic epidermal necrosis (TEN). A 33-year-old man presented with erythematous eroded papules and patches on his head, neck, and upper chest over 2 months. Moreover, he showed hemorrhagic crusted erosions on his lips, and buccal and nasal mucosa, in addition to conjunctival injection. A skin biopsy from his cheek showed a mild degree of vacuolar alteration, thickening of the basement membrane, perivascular and periadnexal lymphohistiocytic infiltration, and stromal mucin deposition. Direct immunofluorescence (DIF) demonstrated IgG and IgM deposits along the basement membrane zone. Laboratory investigations demonstrated pancytopenia, positive antinuclear antibody (ANA), anti-double stranded DNA (anti-dsDNA), and anti-Ro antibodies. The patient was diagnosed with systemic lupus erythematosus (SLE) based on clinical, histological, and laboratory markers of autoimmune disease. We report a rare case of SLE presenting as SJS. (Korean J Dermatol 2017;55(5):293∼296)
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이경근 ( Kyoung Geun Lee ),고병용 ( Byoung Yong Koh ),권은선 ( Eun Sun Kwon ),명기범 ( Ki Bum Myung ),정승현 ( Seung Hyun Cheong ) 대한피부과학회 2018 대한피부과학회지 Vol.56 No.1
Crohn’s disease is a chronic granulomatous disease involving any part of gastrointestinal tract. The skin is a common site of extraintestinal involvement in Crohn’s disease. The most common sites of cutaneous involvement in Crohn’s disease are the perineal and perianal areas. Cutaneous Crohn’s disease is relatively common among those previously diagnosed with gastrointestinal Crohn’s disease. A 22-year-old woman presented with a history of a tender erythematous swelling on the vulva, predominantly on the right side, for several months. She had no previous medical history, including Crohn’s disease. Histopathologic examination on the right side of labium majus showed upper dermal edema and granulomatous non-caseating necrosis composed of multinucleated giant cells, as well as perivascular and interstitial lymphoplasmocytic infiltration in the dermis. Under gastroenterology consultation, endoscopic examination was performed. Colon biopsy revealed chronic inflammation with lymphoplasmocytic infiltration, consistent with the active stage of Crohn’s disease. Herein, we report a rare case of Crohn’s disease initially presenting as vulvar swelling. (Korean J Dermatol 2018;56(1):49∼52)
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Acitretin으로 치료된 다발성 거대각질가시세포종 1예
권은선 ( Eun Sun Kwon ),이경근 ( Kyoung Geun Lee ),고병용 ( Byoung Yong Koh ),명기범 ( Ki Bum Myung ),정승현 ( Seung Hyun Cheong ) 대한피부과학회 2017 대한피부과학회지 Vol.55 No.4
Giant keratoacanthoma is an uncommon variant of keratoacanthoma, which may increase to a diameter of several centimeters. Although keratoacanthomas usually resolve spontaneously, giant keratoacanthoma can be invasive and destructive. A 49-year-old man presented with a 5-year history of multiple large hyperkeratotic and crusted plaques and nodules on sun-exposed areas such as the face, ear, hand, and forearm. Some lesions involuted spontaneously, whereas others became rather enlarged. The biopsy specimen revealed horn-filled crater formation, epidermal extending resembling a buttress, and an eosinophilic glassy appearance in the keratinocytic cytoplasm. We treated the lesions with acitretin, and they almost completely resolved after 13 weeks. Here we describe a case of multiple giant keratoacanthoma treated with acitretin. (Korean J Dermatol 2017;55(4):249∼252)
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