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급성 중심장액맥락망막병증 환자에서 유리체내베바시주맙 주입술의 유용성
고경민,김주연,김종우,최문정,Kyung Min Koh,Joo Yeon Kim,Jong Woo Kim,Moon Jung Choi 대한안과학회 2012 대한안과학회지 Vol.53 No.6
Purpose: To evaluate the efficacy of intravitreal bevacizumab injection (IVB) in acute central serous chorioretinopathy. Methods: Retrospective chart review of 87 eyes of 80 patients. They received intravitreal bevacizumab injection (n = 40) and observed without any treatment or any medication (n = 47) for initial treatment of acute CSC. Patient demographics and best-corrected visual acuity (BCVA), central macular thickness (CMT) at baseline were analyzed. Then we had regular follow-ups of BCVA and CMT. Results: All patients showed improvement in visual acuity and resolution of subretinal fluid following treatment. In the bevacizumab-treated group, the mean BCVA improved from 0.22 ± to 0.11, mean CMT fell from 361.33 to 185.33 (μm) and recurrence rate was 47%. The conservative-treated group showed an improvement in BCVA from 0.23 at baseline to 0.14, mean CMT fell from 349.65 to 193.41 (μm) and recurrence rate was 70% (p = 0.130, p = 0.908 and p = 0.030, respectively). However, the change of BCVA and CMT of 2 groups showed no differences at any follow-up visit. Recurrence rate was significantly low in bevacizumab-treated group. Conclusions: The bevacizumab-treated group had relatively low rates of recurrence in acute CSC patients compared to the observation group. However, intravitreal bevacizumab showed no positive effect in BCVA and CMT of acute CSC patients compared to the observation group. Further investigation will be helpful to understand this therapy in patients with CSC. J Korean Ophthalmol Soc 2012;53(6):781-785
두 가지 저함수율 비이온계 실리콘 하이드로겔 치료용 콘택트렌즈에 따른 굴절교정레이저각막절제술 후 통증의 비교
고경민(Kyung Min Koh),한상윤(Sang Youn Han),권영아(Young A Kwon),송상률(Sang Wroul Song),김병엽(Byoung Yeop Kim),김용란(Yong Ran Kim),손용호(Yong Ho Sohn),정재림(Jae Lim Chung) 대한검안학회 2015 Annals of optometry and contact lens Vol.14 No.2
Purpose: To compare of the pain after photorefractive keratectomy (PRK) according to two kinds of silicone hydrogel contact lenses. Methods: 92 eyes of 46 patients who underwent PRK surgery were prospectively investigated. Each patient was randomly assigned senofilcon A in one eye and lotrafilcon B in the other eye. Pain score (0-10) was assessed at postoperative day 0, 1, 2, 3 and 4 using visual analogue scale. Results: The pain scores (mean ± SD) of senofilcon A and lotrafilcon B were 1.6 ± 1.4, 2.2 ± 1.5 on postoperative day (POD) #0 (p = 0.0029), 2.9 ± 1.5, 3.7 ± 1.5 on POD # 1 (p = 0.009), 2.1 ± 1.2, 2.2 ± 1.4 on POD #2 (p = 0.6208), 0.5 ± 0.7, 0.7 ± 0.8 on POD #3 (p = 0.8375), and 0.1 ± 0.3, 0.1 ± 0.3 on POD #4 (p = 0.1332) respectively. Conclusions: Senofilcon A contributed to reduce postoperative pain effectively in patients undergoing PRK due to lens design, material and moisture-rich properties.