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      • KCI등재

        한 정신건강의학과에 내원한 북한이탈주민의 정신의학적 문제 고찰

        강희영,변성혜,신상호,김현정,이소희,유소영,Kang, Hee-Young,Byeon, Seong-Hye,Shin, Sang-Ho,Kim, Hyun-Chung,Lee, So-Hee,Yoo, So-Young 대한수면의학회 2012 수면·정신생리 Vol.19 No.1

        Purpose: According to the statistics announced by the Ministry of Unification, the number of North Korean refugees living in South Korea has increased by 200 on average monthly in 2010. The number of refugees increased only by 300 annually until 2000. The total number of refugees as of February 2012 was 20,956. This study aims to investigate the psychobiology of the North Korean refugees who consulted psychiatric clinics among those living daily life in South Korea. Methods: The subjects of this study were 85 North Korean refugees that consulted psychiatric clinics from January 1, 2005 to July 2011. This study obtained demographic and psychiatric information in a retrospective approach. Results: Among the 85 North Korean refugees, 75 (88.2%) were females and their average age was 48 years of age. A total of 16 (18.8%) were admitted to a clinic and among the inpatients, 4 were admitted twice and two were admitted three times. As for the claimed symptoms of outpatients, insomnia was shown in 47 (55.3%) patients, headaches in 37 (43.5%), anxiety in 20 (23.5%), depression in 19 (22.4%), etc. The major symptoms represented by inpatients were insomnia in 14 (87.5%) patients, depression in 12 (75%), and headaches in 8 (50%), etc. Conclusion: The most frequent psychiatric symptoms of North Korean refugees living in South Korea were insomnia and headaches. It suggests that when performing psychiatric diagnosis and treatment of North Korean refugees, we have to take into consideration the fact that they claimed the physical symptoms more than the emotional ones. Also, from the aspect that most symptoms of North Korean refugees were insomnia, more profound research on sleep is required in the future. 목 적 : 본 연구에서는 이미 정착하여 일상 생활을 하고 있는 북한이탈주민들 중 정신과 진료를 받은 환자들을 대상으로 정신생리를 고찰하고자 하였다. 방 법 : 본 연구는 2005년 1월 1일부터 2011년 7월까지 정신과를 내원한 북한이탈주민 환자 85명을 대상으로 후향적으로 인구학적 정보 및 정신과적 정보를 획득하였다. 결 과 : 85명의 북한이탈주민 중 75명(88.2%)이 여자였으며, 평균연령은 48세였다. 외래에서 주로 호소한 증상으로는 불면 47명(55.3%), 두통 37명(43.5%), 불안감 20명(23.5%), 우울감 19명(22.4%) 등이었으며, 입원시 주된 증상은 불면 14명(87.5%), 우울감 12명(75%), 두통 8명(50%) 등이었다. 결 론 : 국내에 입국해서 생활하고 있는 북한이탈주민들이 가장 많이 호소하는 정신과적 증상은 불면, 두통 등으로 나타났다. 향후 북한이탈주민들을 정신과적 평가 및 치료함에 있어서 정서적 호소보다 신체적 증상을 더 많이 호소하는 특징을 고려하여야 함을 시사한다. 또한 북한이탈주민들의 가장 많은 증상이 불면이었다는 점에서 향후 이들을 대상으로 수면에 대한 심도 있는 연구가 이루어야 할 것이다.

      • KCI등재

        투명각막 절개를 통한 백내장 수술 후 발생한 각막상피내생의 치료

        강희영,신민철.Hee Young Kang. MD. Min Chul Shin. MD 대한안과학회 2009 대한안과학회지 Vol.50 No.2

        Purpose: To report a case of epithelial ingrowth treatment by surgical excision of epithelial tissues and intracameral 5-fluorouracil injection. Case summary: A 70-year-old female patient who underwent phacoemulsification through clear cornea incision in both eyes 2 years before, was referred for her left ocular pain and corneal edema of 3 months' duration. Diffuse sheet-like epithelium grew from the clear cornea incision site to the pupil margin lesion of the iris. The epithelial tissues were excised and 5-fluorouracil was injected intracamerally. There were no recurrences for 2 months.

      • KCI등재

        Enterococcus faecalis 특이적 박테리오파지의 분리와 특성규명

        강희영,김석호,김정민,Kang, Hee-Young,Kim, Shukho,Kim, Jungmin 한국미생물학회 2015 미생물학회지 Vol.51 No.3

        Enterococcus faecalis는 그람 양성의 조건 혐기성 세균으로 원내감염의 주요 원인균 중의 하나이다. E. faecalis에 특이적인 신규 박테리오파지 ECP3를 환경에서 분리하여 형태와 유전적 특성을 규명하였다. ECP3 파지는 형태적으로 수축성 꼬리를 갖는 미오비리대 과에 속하며 E. faecalis를 특이적으로 사멸하지만 Enterococcus faecium를 포함한 다른 세균은 사멸시키지 않았다. ECP3 파지의 게놈은 이중 선형 DNA로 GC 함량이 35.9%이었으며 크기가 145,518 bp이며 220개의 구조유전자로 구성되어 있었다. ECP3 게놈과 가장 유사한 염기서열은 미오비리대 PhiEF24C 파지이었으며 전체 게놈 90%의 영역에서 97%의 유사도를 보였다. ECP3 파지는 한국에서 처음 분리된 E. faecalis 미오비리대 파지이며 E. faecalis 감염에 대한 신규 항균제로서 유망하다. Enterococcus faecalis is a Gram-positive and facultative anaerobic bacterium that causes many hospital-acquired infections. Novel E. faecalis specific bacteriophage (phage) ECP3 that had been isolated from thirty-four environmental samples and characterized phenotypically and genotypically. ECP3 phage belongs to the family Myoviridae with contractile tail and lysed E. faecalis specifically but other bacteria including Enterococcus faecium. The genome was double-stranded linear DNA and its size was 145,518 bp comprising of 220 open reading frames. The GC content was 35.9%. The genome sequence showed 97% identity in 90% coverage region with Myoviridae phage PhiEF24C. ECP3 is the first E. faecalis-specific Myoviridae phage isolated in Korea which can be a promising antimicrobial agent against E. faecalis infections.

      • KCI등재

        만성 간염환자에서의 페기레이티드 인터페론 망막증

        강희영,임지원,신민철,Hee Young Kang,Ji Won Lim,Min Chul Shin 대한안과학회 2009 대한안과학회지 Vol.50 No.3

        Purpose: To investigate clinical features of pegylated interferon‐associated retinopathy in chronic hepatitis patients. Methods: The present study was a consecutive case series of 46 patients who were treated with pegylated interferon for chronic hepatitis C or B from October 2007 to September 2008 in our hospital. The patients had a regular ophthalmologic examination every 3 weeks for 6 months after treatment. Results: Out of 46 patients, 10 patients (21.73%) developed retinal abnormality. Pegylated interferon‐associated retinopathy occurred at 7.25±10.28 weeks after the treatment with cotton‐wool spots and retinal hemorrhage. All cases except one mild nonproliferative diabetic retinopathy case presenting broad perimacular non‐perfusion recovered without cessation of the treatment. Conclusions: Pegylated interferon‐associated retinopathy in chronic hepatitis patients was reversible and had a recovery without visual complication. However, a single case did present with irreversible visual impairment. Pegylated interferon‐associated retinopathy is usually asymptomatic and clinicians should observe patients closely for 3 months after treatment.

      • 가변 흡기시스템이 과급 디젤엔진의 체적효율 향상에 미치는 영향

        강희영(Heuiyeong Kang),고대권(Daekwon Koh),안수길(Sookil Ahn),장재은(Jaeeun Jang) 한국자동차공학회 2006 한국자동차공학회 춘 추계 학술대회 논문집 Vol.- No.-

        A variable induction system applied to a turbo-charged diesel engine was investigated in various ways for the purpose of improvement of the volumetric efficiency in a low and transient engine speed that can reduce emission level for a diesel engine. The basic concept of this model derived from the theory that the long period component affects to the volumetric efficiency in a low engine speed range. The volumetric efficiency is known to be directly proportioned to engine brake horse power and affects significantly to the engine performance ; torque characteristics, fuel economy and emission level. Since the engine is designed so as to produce their best performance near the normal engine speeds, the volumetric efficiency of the low engine speed range has a tendency of poor value for commercial vehicles and stationary engines. The aim of this study was focused on the improvement of volumetric efficiency of low engine speed range in a turbo-charged multi-cylinder diesel engine by using an additional Helmholtz resonator coupled with variable secondary induction pipe. Several results were depicted which deal with the history of the pulsating wave in the primary induction pipe and the depression wave diagram during intake process, which is very useful to estimate and predict the volumetric efficiency and the intake system configuration at the stage of pre-designing. Cutting and welding methods was applied to this investigation.

      • Symposium 5-3 (SYP 5-3) : Factors influencing on skin pigmentation

        강희영 ( Hee Young Kang ) 대한피부과학회 2014 대한피부과학회 학술발표대회집 Vol.66 No.2

        Skin pigmentation is regulated by interactions between melanocytes and neighboring cells, such as keratinocytes, fibroblasts or inflammatory cells. Up- or downregulation of paracrine factors secreted from these cells control melanocyte functions and cause pigmentary changes. Several clinical examples underline the importance of dermal factors in the control of epidermal pigmentation. Human dermal fibroblasts secrete several paracrine factors including stem cell factor (SCF), keratinocyte growth factor (KGF), Wnt inhibitory factor 1 (WIF-1), neureguln-1, Dickkopt-related protein 1 (DKK1), and pleiotrophin. The fibroblast activity is regulated by extrinsic factors such as ultraviolet radiation. Understanding of the roles of proteins secreted from neighboring skin cells in the function of melanocytes may provide valuable information regarding the development of target proteins for treatment and a better understanding of the pathophysiology of cutaneous pigmentation.

      • Board Exam. Prep. Course 2-3 (BEPC 2-3) : Melanocytes and mast cells

        강희영 ( Hee Young Kang ) 대한피부과학회 2014 대한피부과학회 학술발표대회집 Vol.66 No.2

        Melanoblasts derived from the neural crest migrate and differentiate into melanocytes in the epidermis and hair follicle. Their migration/ survival in the epidermis is influenced by numerous factors including Wnt, endothelin-3, and stem cell factor. Epidermal melanocytes synthesize melanin pigments in specialized cellular organelles called melanosomes, which are transported from melanocytes to adjacent keratinocytes. Tyrosinase is a rate-limiting enzyme in melanin synthesis. MC1R genetic polymorphisms are responsible for ethnic differences of constitutive pigmentation and for different responses to UVR exposure. Skin pigmentation by UV radiation is regulated by multiple factors secreted by cells neighboring melanocytes including keratinocytes, fibroblasts or inflammatory cells. Many biological factors including α-MSH are implicated in the pigmentation and tanning response by UV irradiation. p53 is a transcription factor that plays a pivotal role in the tanning response after UVB-induced DNA damage. Mast cells are specialized secretory cells in the dermis which are responsible for immediate-type hypersensitivity reaction in skin and are involved in the inflammatory reaction.

      • KCI등재
      • KCI등재

        Health Habits and Obesity according to Sasang Constitutionamong Female College Students in Korea

        강희영(Hee Young Kang),이점덕(Jeom Duck Lee),김계하(Kye Ha Kim) 한국사회체육학회 2011 한국사회체육학회지 Vol.0 No.43

        본 연구에서는 여대생의 사상체질을 판별하고, 사상체질에 따른 건강습관과 비만 정도를 분석함으로써 사상체질에 따른 적절한 건강유지및 증진을 위한 맞춤식 간호중재법 개발의 기초자료를 마련하고자 한다. 본 연구의 대상자(subjects)는 G시에 거주하는 여대생을 대상으로 2007년 6월부터 9월까지 비무작위 편의추출(nonrandomized convenient sampling)로 선정하였다. 대상자의 체질을 감별하기 위하여 사상체질 진단에 임상적으로 많이 활용되며 그 객관성이 인정되고 있는 사상체질분류검사지 QSCCⅡ(Questionnaire for Sasang Constitution Classification Ⅱ)를 사용하였다(김선호 외, 1996). 대상자들의 건강습관을 확인하고자 음주, 흡연, 운동, 식습관의 총 4문항에 대하여 측정한 것을 의미한다. 대상자의 일반적 특성과 사상체질별 구성비, 건강 습관과 비만 정도를 알아보기 위해 기술통계를 구하였다. 사상체질에 따른 건강 습관과 비만 정도의 차이는 chi-square test와 one-way ANOVA로 검증하였다. 연구 분석 결과, 대상자의 사상체질 분포를 살펴보면 소음인이 57.3%로 가장 많았고, 소양인은 23.8%, 태음인 18.9%였다. 태양인은 한 명도 없는 것으로 나타났다. 본 연구의 대상자들은 사상체질에 따라 음주, 흡연, 규칙적 운동, 식습관 등의 건강 습관에 유의한 차이가 없었다. 비만 정도는 사상체질에 따라 BMI, 체지방량, 체지방률, 복부지방율, 내장지방이 통계적으로 모두 유의한 차이가 있었는데, 태음인이 소양인과 소음인에 비해 비만 정도가 모두 높은 것으로 나타났다. 따라서 태음인이 다른 집단들에 비해 비만하기 쉬운 체질인 것으로 보여지므로 체질에 따른 비만관리를 해 줄 필요가 있을 것이다.

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