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      • KCI등재
      • KCI등재

        躁鬱症에 關한 臨床的 考察

        韓東洙 大韓神經精神醫學會 1969 신경정신의학 Vol.8 No.2

        The focus of this study is to investigate the symptomatic aspects of manic-depressive illness in Korea. In this study the author tried to analyze the symptoms of 54 manic-depressive patients who were selected among 1868 inpatients admitted to Seoul National University Hospital from 1960 to 1967. 1. The ratio of M.D.I. to total patients treated furing the stated period was 2.8%, indicating remarkably lower incidence compaired to other researches in the past. It may be that they have not reached mental hospitals because their sick role was not sufficiently recognized in the community as such. 2. There were 34 males and 20 females, and male to female ratio was 1.7:1. 3. The patients were devided into groups according to the age of onset of lst atack. The largest group had their lst onset between the ages of 20 to 30, after that age group of between 30 to 40. Generally, females tended to have their lst attack rather at younger age than males. 4. Depressive patients tended to stay shorter period of time in the hospital than manic patients. It is thought that electroconvulsive treatments for the depressive patients brought about rather rapid relief of symptoms. 5. The largest age group of all patients was in the 3rd decade and the next 2nd decade. 6. Their symptomes were classified into psychologic complaints and somatic ones. 7. Both elated and depressives suffered from bad mood, discomfort although a numbers of manics oppressed unplanned, irregular overactions. 8. In the depressives, author found that depressions were mixed with self-reproachful guilt closely related to Korean tradition and conventions, within highly cohesive family framework.

      • KCI등재

        最近 8年間의 精神神經科 入院 外來 및 患者에 對한 統計的 考察(1960年∼1967年)

        李哲奎,盧英一,張煥一,金明源,任允明,韓東洙,吳承煥,金光日 大韓神經精神醫學會 1969 신경정신의학 Vol.8 No.1

        1) The number of the out-and in-patients had increased year after year (Table Ⅰ & Ⅲ). 2) Schizophrenia was the greatest number of the in-patients and its rate to whole was 49.1 percent, and neurosis was the greatest number of the out-patients and its rate to whole was 41.66 per cent (Table Ⅰ & Ⅶ). 3) In in-patients, hysteria revealed relatively large in percentage as 11.8% than the other groups (Table Ⅰ). 4) The rate of the male hysteria patients to all male patients was 3.5 per cent and the rate of female hysteria was 20.5 per cent (Table Ⅱ). 5) In in-patients, all the patients of general paresis and alcoholism were only males in sex(Table Ⅱ). 6) In in-patients of schizophrenia, the ratio of the male patients to the female patients was 57.0 : 43.0, but the each rate of each total numbers of the all diseases of the both sexes was almost same (Table Ⅲ). 7) The largest age group of the all patients was between 21∼30 years old, and the next was between 31∼40 years in in-patients (Table Ⅲ). 8) The largest age group of schizophrenia patients was between 21∼30 years and that of M.D.R patients was between 31∼40 years in in-patients (Table Ⅲ). 9) In in-patients of hysteria, the largest age group was between 31∼40 years, and the next was between 21∼30 years (Table Ⅲ). 10) The results of treatment in in-patients were as followings; Recovered; 27.6% Much improved; 43.1% Slightly improved and no changed; 28.2% (Table Ⅳ) 11) The results of treatment in schizophrenia of the in-patients were as followings; Recovered; 19.1% Much improved; 48.3% Slightly improved and no changed; 32.1% (Table Ⅴ) 12) The mode of treatment had been somewhat changed during last 8 years from 1960 to 1967 in treatment of the in-patients (Table Ⅵ). (1) The combined therapy of tranquilizers and EST had been increased, but the therapy of tranquilizer alone or EST alone had been decreased, compared to 1960. (2) The therapy of ICT in the treatment of in-patients had been much decreased.

      • KCI등재

        Lithium Carbonate distribution and its effects on the other ions in the brain and the other tissue of rats

        Hahn, Dong Soo,Lee, Chung Kyoon 大韓神經精神醫學會 1975 신경정신의학 Vol.14 No.4

        Lithium이 臨床的으로 情緖障碍治療에 利用되기 始作한 것은 最近에 와서 活發해 졌다. 그러나 其效果의 作用機轉은 아직 明確치 않음으로 Lithium carbonate를 動物에 投與하여 腦 및 其他 組織에 어떻게 分布되며 다른 電解質과의 關係가 어떤지를 究明하고 其作用機轉을 理解하고져 本實驗을 施行하여 다음과 같은 結果를 얻었다. 1. Lithium分布는 腦뿐아니라 大部分의 器官組織에서 大量短期投與群에서 小量長期投與群보다 濃度가 높았다. 그러나 腦下垂體와 副腎에서는 그렇지 않다. 2. 腦의 Na. K. ion濃度는 正常群보다 大量短期投與群에서 減少되었고 Ca. ion濃度는 血漿濃度가 가장낮은 大量短期投與群과 正常群의 差異가 거의 없고 Mg.의 血漿濃度는 大量短期投與群에서 가장 높았으나 腦組織의 濃度는 正常群과 別差없다. 3. 正常群에서는 筋과 腦에 비슷한 Lithium이 存在하나 大量短期投與群에서는 筋組織으로의 浸透速度가 빠르고 많다. 4. Lithium Carbonate 投與後 各組織에서의 電解質變化를 보면 다음과 같다. 血漿에서는 Ca. ion이 大量短期投與群에서 正常群보다 減少하나 小量長期投與群에서는 多少 增加하였다. 血漿, 赤血球 및 腎에서 Mg値가 Lithium carbonate 投與群에서 上昇하였고 筋에서는 正常群과 比較해서 K. Ca.이 增加, Ca.는 骨에서는 減少하고 심장, 肝, 腎에서는 增加했다. 5. RBC/plasma Ratio는 正常群보다 大量短期投與群에서 上昇하였고 小量長期投與群에서는 더욱 上昇하였다. 이것은 赤血球의 Lithium-up-take가 느리다는 것을 意味한다. 1. Infiltration and distribution rates of lithium into the brain as well as most organs except hypophysis and adrenal glands were higher in the group received large quantity for short period than in the group received small dose for longer period. 2. Concentration of Na and K ions in the brain were lower in the group received large doses for shorter period than in the controls. There was no significant difference in the level of Ca ion concentration between the controls and the group which received large doses for short period and which also showed the lowest plasma level. Plasma level of Mg was highest in the group received large doses for short period but the concentration of Mg in the brain was almost same as in the controls. 3. In the control group the amount of lithium is almost same in the muscle and in the brain, but in the group received large doses for short period the infilteration rate of lithium was higher and the amount of the infiltrate was larger in the muscle. 4. The changes of electrolites in the various tissues after administration of lithium carbonate were as follows: In plasma Ca ion decreased more in the group received large doses for short period than in the controls but in the group received small amount for longer period it rather increased a little. In the groups that received lithium, level of Mg in plasma, RBC and the kidney increased, K and Ca increased in the muscles in comparison with the controls, and Ca decreased in the bones and increased in the heart, liver and kidney. 5. RBC/plasma ratio increased more in the group received large doses for short period than in the control group, and it increased much more in the group received small dose for longer period. This suggests lithium uptake of RBC is slow.

      • THE CAST SYNDROME : Report of a Case

        金東垠,金顯周,韓董洙 中央醫學社 1941 中央醫學 Vol.10 No.5

        A case of cast syndrome is presented and the previously described cases are reviewed. In our case, 44 years old male developed pernicious vomiting and abdominal distension, 21 hours after being placed in single hip spica cast because of the subtrochauteric fracture of the left femur. X-rays of the abdomen revealed markedly distended stomach. The patient responded well to conservative management.

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