Dynamic analysis of train-bridge interaction system with flexible car-body

Wang Kunpeng,Xia He,Xu Man,Guo Weiwei 대한기계학회 2015 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.29 No.9

Lighter vehicles are used in high-speed trains and urban rail transit trains, which leads to lesser stiffness of car-bodies, so car-bodyflexibility should be considered in dynamic analysis of the train-bridge system. In this paper, the vehicle model is established based onflexible multi-body dynamics, in which the car-body is simulated with an Euler beam, and the movement of the car-body is the superpositionof its rigid displacement and the generalized displacement of vibration mode of the Euler beam with free boundaries. The dynamicanalysis model of train-bridge model is established using the flexible car-body model. A case study is performed of an ICE3 train runningon a (48+80+48) m three-span continuous girder bridge. The calculated results show that the car-body flexibility has little influence onbridge responses and vehicle running safety indices, but great influence on car-body accelerations. It is necessary to consider the car-bodyflexibility, especially in studying the influence of additional bridge deformations on vehicle responses.

Human Papillomavirus Vaccine Awareness, Acceptability, and Decision-Making Factors among Chinese College Students

Wang, Shao-Ming,Zhang, Shao-Kai,Pan, Xiong-Fei,Ren, Ze-Fang,Yang, Chun-Xia,Wang, Zeng-Zhen,Gao, Xiao-Hong,Li, Man,Zheng, Quan-Qing,Ma, Wei,Zhao, Fang-Hui,Qiao, You-Lin,Sivasubramaniam, Priya Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.7

Background: College students are recommended as the target groups for catch-up human papillomavirus (HPV) vaccination. Systematical exploration of awareness, acceptability, and decision-making factors of HPV vaccination among Chinese college students has been limited. Materials and Methods: A multi-center survey was conducted in mainland China between November 2011 and May 2012. College students aged 18-22 years were stratified by their grade, gender, and major for sampling. Socio-demographic and HPV-related information such as knowledge, perceptions, acceptability, and attitudes were collected through a questionnaire. Results: A total of 3,497 undergraduates completed the questionnaire, among which 1,686 were males. The acceptability of the HPV vaccine was high (70.8%). Undergraduates from high-level universities, at lower grade, or with greater prior knowledge of HPV vaccines showed higher acceptability of HPV vaccination ($p_{trend}$ <0.001). Additionally, undergraduates with vaccination experience outside the National Expanded Program on Immunization (OR=1.29; 95%CI: 1.10-1.51) or fear of HPV-related diseases (OR=2.79; 95%CI: 2.28-3.41) were more willing to accept HPV vaccination. General knowledge of HPV vaccine was low among undergraduates, and safety was a major concern (71.05%). The majority of students wished to pay less than 300RMB for HPV vaccine and chose the Chinese Center for Disease Control and Prevention as the most appropriate venue for vaccination. Conclusions: Although most undergraduates demonstrate positive attitudes towards HPV vaccination, challenges pertaining to introduction exist in China. Corresponding proactive education and governmental subsidy to do so are urgently needed by this age-group population. Suggestions and potential strategies indicated may help shape the future HPV vaccination program in China.

Research on Flexible Business Process of Bank Modeling Based on EPC

Wang Xia,Man Junpeng,Liu Lan 보안공학연구지원센터 2015 International Journal of Multimedia and Ubiquitous Vol.10 No.6

As the further development of banking business for personalization and diversification, the bank information system is capable of dynamically adjusting business process and has set higher requirements for the flexible mechanism. This paper constructs a model of the business process based on Event-driven Process Chains (EPC), puts forward the concrete specification in the process of construction. A case study was implemented to validate the model using Pi-calculus. The results show that this model can be a powerful tool for the creation of flexible or customized business process.

Coupling vibration response analysis of wind-train-bridge system considering the train-induced wind effect

Yujing Wang,Weiwei Guo,He Xia,Shanshan Wang,Man Xu 한국풍공학회 2021 Wind and Structures, An International Journal (WAS Vol.33 No.3

Considering the wind loads and track irregularity as external excitation, the wind-train-bridge dynamic analysis model considering the longitudinal freedom of train is established in the present study. In the model, the wind load of trainbridge system under the train-induced wind field and the combined wind field is obtained by employing Computational Fluid Dynamics (CFD) method. With the CRH2 high-speed train and a 10-span simply-supported box girder bridge as an example, the whole history of the train running on the bridge under the combined effect of train-induced wind and crosswind is simulated to analyze the dynamic response of the train-bridge system. In addition, the operational safety indicators of the train are evaluated. According to the obtained results, the dynamic response of vehicles and bridges increases with the train speed without the consideration of the crosswind. In the combined wind field, the train-induced wind exerts a greater impact on the dynamic response of the vehicle, but has a less influence on that of the bridge simultaneously. Moreover, the influence of wind velocity is greater than that of train speed. When the wind-train-bridge dynamic response analysis is carried out based on traditional methods, the calculated wind load of the train-bridge system is too high, making the calculated responses too large to be consistent with actual values.

A preparation and performance study of glass-ceramic glazes derived from blast furnace slag and fly ash

Hong-xia Lu,Man He,Yuan-yuan Liu,Jing-fei Guo,Li-wei Zhang,Deliang Chen,Hai-long Wang,Hong-liang Xu,Rui Zhang 한양대학교 세라믹연구소 2011 Journal of Ceramic Processing Research Vol.12 No.5

Glass-ceramic glazes have been prepared successfully via crystallization from blast-furnace slag (BFS), fly ash (FA) fluxed with potash feldspar and borax. The crystalline behavior of glass-ceramic glazes was investigated using differential thermal analysis and thermogravimetric analysis (DTA/TG), X-ray diffraction (XRD) and scanning electron microscopy (SEM). Results revealed that the major crystalline phases are anorthite (CaAl2Si2O8) and akermanite (Ca2MgSi2O7) and crystalline phases disperse well in glassy phases with a uniform size of 1 μm. Glass-ceramic glazes possess low density, low water absorption,perfect stain resistance, acid resistance and alkali resistance. The thermal expansion coefficient of glass-ceramic glazes is steady up to 800 oC with an average value of 7.2 × 10−6 /K. Final results suggest that BFS and FA have potential to be vitrified into economically and environmentally low-cost glass-ceramic glaze materials.

Study on the Anti-hypertension mechanism of Prunella Vulgaris based on entity grammar systems

Li Du,Man-man Li,Bai-Xia Zhang,Shuai-Bing He,Ya-Nam Hu,Yun Wang 셀메드 세포교정의약학회 2015 셀메드 (CellMed) Vol.5 No.4

Literatures and experimental studies have shown that Prunella has an effect on anti-hypertension, however, its components are complicated, so that it is still difficult to clear the specific roles of its various components in blood pressure regulation in. So we decide to systematically study the anti-hypertension mechanism of Prunella. We integrated multiple databases and constructed molecular interaction network between the chemical constituents of Prunella Vulgaris and hypertension based on entity grammar systems model. The network has 262 nodes and 802 edges. Then we infer the interactions between chemical compositions and disease targets to clarify the anti-hypertension mechanism. Finally, we found Prunella could influence hypertension by regulating apoptosis, cell proliferation, blood vessel development and vasoconstriction, etc. Thus this study provides reference for drug development and compatibility, and also gives guidance for health care at a certain extent.

Transcatheter Arterial Chemoembolization Combined with Interferon-α is Safe and Effective for Patients with Hepatocellular Carcinoma after Curative Resection

Zuo, Chaohui,Xia, Man,Liu, Jingshi,Qiu, Xiaoxin,Lei, Xiong,Xu, Ruocai,Liu, Hanchun,Li, Jianliang,Li, Yongguo,Li, Qinglong,Xiao, Hua,Hong, Yuan,Wang, Xiaohong,Zhu, Haizhen,Wu, Qunfeng,Burns, Michael,Li Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.1

Objectives: Intrahepatic recurrence is the major cause of death among patients with hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) after curative surgical resection. Several approaches have been reported to decrease the recurrence rate. The objective of our study was to compare the clinical effects of transcatheter arterial chemoembolization (TACE) combined with interferon-alpha (IFN-${\alpha}$) therapy on recurrence after hepatic resection in patients with HBV-related HCC with that of TACE chemotherapy alone. Methods: We retrospectively analyzed the data from 228 patients who were diagnosed with HBV-related HCC and underwent curative resection between January 2001 to December 2008. The patients were divided into TACE (n = 126) and TACE-IFN-${\alpha}$ (n = 102) groups for postoperative chemotherapy. The TACE regimen consisted of 5-fluorouracil (5-FU), cisplatin (DDP), and the emulsion mixed with mitomycin C (MMC) and lipiodol. The recurrence rates, disease-free survival (DFS), overall survival (OS), and risk of recurrence were evaluated. Results: The clinicopathological parameters and adverse effects were similar between the 2 groups (P > 0.05). The median OS for the TACE-IFN-${\alpha}$ group (36.3 months) was significantly longer than that of the TACE group (24.5 months, P < 0.05). The 3-and 5-year OS for the TACE-IFN-${\alpha}$ group were significantly longer than those of the TACE group (P < 0.05) and the recurrence rate was significantly lower (P < 0.05). The TACE and IFN-${\alpha}$ combination therapy, active hepatitis HBV infection, the number of tumor nodules, microvascular invasion, liver cirrhosis, and the BCLC stage were independent predictors of OS and DFS. Conclusions: The use of the TACE and IFN-${\alpha}$ combination chemotherapy after curative hepatic resection safely and effectively improves OS and decreases recurrence in patients with HBV-related HCC who are at high risk. Our findings can serve as a guide for the selection of postoperative adjuvant chemotherapy for patients with HBV-related HCC who are at high risk of recurrence.

Separation and Determination of the Volatile Oil of the Parts of the Ginseng Growing on the Ground

(Yun Xiu Sun),(Kun Yuan Mao),(Wen Pu Jang),(Feng Wen Li),(Man Xia Wang),(Wen Min Zhou),(Zong Guang Sun) 고려인삼학회 1990 Proceedings of International Symposium on Korean G Vol.- No.-

OsCML4 improves drought tolerance through scavenging of reactive oxygen species in rice

Xu Ming Yin,Li Fanng Huang,Xin Zhang,Man Ling Wang,Guo Yun Xu,Xin Jie Xia 한국식물학회 2015 Journal of Plant Biology Vol.58 No.1

Calmodulin-like (CML) genes function in regulating plant responses to different abiotic stresses, such as high salt and drought. Using japonica type rice seedlings (‘Nipponbare’), we induced the expression of OsCML4 (Accession No. NM_001057768), which encodes a rice CML protein. Under drought conditions, transgenic plants over-expressing that gene exhibited obviously improved growth performance and higher survival rates than the wild type (WT). Activity by reactive oxygen species (ROS)- scavenging enzymes superoxide dismutase (SOD) and catalase (CAT), as well as proline concentrations, were significantly increased in transgenic plants. Expression by ROS scavenging-related genes APXI and Cat-B and the stress-related gene OsP5CS1 was also enhanced in the transgenics under drought conditions. However, the sensitivity to abscisic acid (ABA) was similar between over-expressing and WT plants. These results suggest that OsCML4 confers drought tolerance partially through ROS-scavenging and also by inducing other stress-related genes in an ABAindependent manner.

Rice Gene OsDSR-1 Promotes Lateral Root Development in Arabidopsis Under High-Potassium Conditions

Xu Ming Yin,Pedro S. C. F. Rocha,Man Ling Wang,Yu Xin Zhu,Luo Ye Li,Shu Feng Song,Xinjie Xia 한국식물학회 2011 Journal of Plant Biology Vol.54 No.3

Rice gene Oryza sativa Drought Stress Response-1 (OsDSR-1) was one of the genes identified to be responsive to drought stress in the panicle of rice at booting and heading stages by both microarray and quantitative real-time PCR analyses. OsDSR-1 encodes a putative calcium-binding protein, and its overexpression in Arabidopsis rendered transgenic plants to produce much shorter lateral roots (LRs) than wild-type (WT) plants in the medium supplemented with abscisic acid (ABA), suggesting that OsDSR-1 may act as a positive regulator during the process of ABA inhibition of LR development. No significant difference was observed in the total LR length between WT and transgenic plants in the media with the increase of only osmotic stress caused by NaCl, LiCl, and mannitol, while transgenic Arabidopsis seedlings appeared to produce larger root systems with longer total LR lengths under highpotassium conditions than WT seedlings. Further analysis showed that external Ca^2+ was required for the production of larger root systems, indicating that the promotion by OsDSR-1 of the LR development of transgenic Arabidopsis seemed to occur in a Ca^2+ -dependent manner under high-potassium conditions. We propose that OsDSR-1 may function as a calcium sensor of the signal transduction pathway controlling the LR development under high-potassium conditions.