권역심뇌혈관질환센터 사업의 비용-편익 분석

김병호 ( Byung Ho Kim ),감신 ( Sin Kam ),배상근 ( Sang Geun Bae ),김건엽 ( Keon-yeop Kim ),이원기 ( Won Kee Lee ),홍남수 ( Nam-soo Hong ),박형근 ( Hyeung-keun Park ),이혜진 ( Heyjean Lee ),조은정 ( Eun-jung Cho ),채성철 ( Shung C 한국보건정보통계학회(구 한국보건통계학회) 2017 보건정보통계학회지 Vol.42 No.1

Objectives: This study was conducted to investigate economic feasibility of operating Regional Cardiocerebrovascular Centers using cost-benefit analysis. Methods: The current study assessed cost and benefit data collected from nine hospitals which were designated as Regional Cardiocerebrovascular Centers between 2008 and 2010. Results: The operation of Regional Cardiocerebrovascular Centers reduced mortality rate and length of stay due to acute myocardial infarction and stroke and also decreased disability occurred after stroke. The total calculated cost of operating nine Regional Cardiocerebrovascular Centers was 19.85-22.30 billion won and the minimum benefit calculated was 23.98 billion won. Applying the maximum cost and the minimum benefit, the net benefit was 1.68 billion won, which is estimated to 190 million won per Regional Cardiocerebrovascular Center. Conclusions: The present study revealed that the operation of Regional Cardiocerebrovascular Centers was economically beneficial. The benefit would be larger if intangible benefit such as the long-term effects to community hospitals and enhancement of quality of life of patients and their families are considered.

3차원 직육면체 대공간 내에서의 열 및 기류 유동에 관한 연구

박원희,이상엽,황문섭,김태국 중앙대학교 기술과학연구소 2002 기술과학연구소 논문집 Vol.32 No.-

본 연구에서는 대공간 내에서의 열 및 기류 유동 현상을 연구하기 위하여 464×300× 950mm^3크기의 축소 모형으로 아트리움을 제작하였다. 가상 화재를 모사하기 위하여 대공간 하단에 히터를 설치하였으며, 히터의 온도에 따른 대공간 내의 온도분포를 측정하였다. 본 실험에서 얻은 결과는 아트리움과 같은 대공간에서 화재가 발생하였을 경우에 열 및 기류 현상을 해석하기 위한 기초자료 및 열유동 현상을 해석하는 수치해석 프로그램의 계산 결과의 기준 데이터로도 이용될 수 있을 것이다.

트랙터 부착용 로더 기구부의 기구학적 시뮬레이션 프로그램 개발

이규승,박원엽,노광모,김준호 성균관대학교 생명공학연구소 1999 生命工學硏究 Vol.5 No.1

A loader mechanism mounted on tractor was modeled for kinematic analysis, and a computer simulation program was developed by using Cartesian coordinate approach, in order to remove the burden of routine derivation and computation from the engineer. The results of kinematic analysis was compared with those of a commercial CAD program. The results of this study was summarized as follows. 1. The results of the simulation showed good agreement with results of the commercial CAD program. This program could be used for predicting the kinematic properties of each links on the loader mechanism. 2. The velocity of bucket which affect the performance of loader increased very quickly just before the finishing point of boom operation, and acceleration also increased sharply at this point. Thus it is concluded that when bucket is rolling, maximum reaction force arises. 3. Velocity and acceleration of each links on the loader mechanism changed very quickly when the bucket cylinder started operation.

마늘 파종기 개발을 위한 재배 측면의 기초 연구

이규승,박원엽 성균관대학교 생명공학연구소 2000 生命工學硏究 Vol.6 No.1

This study was carried out to investigate the labour requirements and cultivation method of garlic production as a basic reference to develop a garlic planter. Fifty households were surveyed for five major garlic production area, or Danyang, Seosan, Eusung, Namhae and Muan. Cultivation field was mainly upland for Danyang, Seosan, and Muan, and lowland for Eusung and Namhae. The slope of fifty five percent of cultivation field was less than 2% and that of 39% of cultivation field ranged from 2 to 30%. For the most of major garlic production area, the width of ridge ranged from 150 to 180 cm except for the Eusung area where ridge ranged from 360 to 400 cm. Furrow width ranged from 30 to 40 cm for the most of the cultivation field. Planting distance was 15∼20 cm and planting width was 5∼10 cm for the most of the cultivation field. Planting depth was 2∼4 cm for Korean local cultivar and 3∼6 cm for Chinese cultivar. For the most of the cultivation area, garlic clove was planted in upright position by ones. For the most of the cultivation area except Muan, plastic film without hole was mulched after planting. Plastic film with 14∼16 hole in a line was used for mulching in muan area.

신수혈의 침자극과 황기약침이 실험용 생쥐의 면역활성물질인 IL-1 α의 遺傳子發現에 미치는 影響

申相習,朴元煥,洪文燁,李泰均,崔達永 대한동의병리학회 1999 동의생리병리학회지 Vol.13 No.2

체내의 환경을 항상적으로 유지하는 생체방어체계에는 면역활성물질이 있으며, 이러한 면역활성물질의 적절한 발현이 생체의 항상성을 유지하는데 작용하게 된다. 이에 한의학에서는 생체의 항상성 유지와 체내의 면역력 증가를 위해 많은 요법들이 시행되어 왔는데, 그 중 자침요법과 약침요법이 많이 응용되고 있다. 그러나 침자극과 약침의 효과에 대한 기전은 기대하는 만큼 제시되지 못하고 있다. 이에 본 논문은 침자극과 약침의 효과에 대한 기전을 밝히는 방법의 일환으로서 면역활성물질인 IL-1α가 補腎臟, 振氣化, 祛水濕, 强腰脊, 益水壯火 등의 穴性이 있는 신수혈(BL23)의 침자극과 황기약침처치를 통해 어떻게 발현하는가를 관찰하였다. 그 결과, 면역 증강 작용을 나타내는 cytokine IL-1α 에 대한 침자극의 반응은 관찰되었고, 황기약침에 의한 IL-1α 의 발현은 명확하지 않았다. 그러므로 신수혈을 이용한 cytokine IL-1α의 추적은 황기약침의 효과보다 침자극의 효과에 대한 근거를 추측할 수 있을 것이며, 뿐만 아니라 침자극에 의한 면역반응정도를 통해 질병의 진행상태를 나타내는 진단지표로서 활용가능성이 있을 것이다. Acupuncture and Radix Astragali aqua-acupuncture stimuli have long been used to cure human diseases. However, it still remains to be unknown on its action mechanism, physiological and biochemical aspects. Thus, many attempts were made to show the scientific background covering the above mentioned mechanisms. Most recent studies show that these tests improve blood circulatory system and increase leucocyte counts. In this study, we have applied the acupuncture stimuli to mouse Sinsu(BL23), which is a stimulative point of oriental medicine, to see if cytokine such as IL-1α can be detected. Mice were treated with lipopolysaccharide(LPS) for inflammation induction, and then reverse transcriptase-polymerase chain reaction (RT-PCR) using each primer set was performed to trace the amounts of mRNA. The results are as follows ; 1. The RT-PCR product using IL-1α primers was detected as 450 bp on agarose gels and the IL-1α gene was not expressed in normal mice at 15 min after the removal of acupuncture. However, it was gradually increased indicating a faint expression after 30 min. 2. IL-1α was expressed in LPS-treated mice 30 min after the acupuncture was pulled out, and expressed most highly at 3 h after the removal of acupuncture. The gene expression of LPS-treated mice were more effective than those of normal mice. 3. IL-1α was not expressed in normal mice and LPS-treated mice from 30 min to 3hs. after Radix Astragali aqua-acupuncture stimulation. Therefore, a tracing the gene expression of cytokine IL-1α can be used more not only for a basis of the effect of acupuncture stimulation but a diagnosis guide through the immunological action than the effect of Radix Astragali aqua-acupuncture. Moreover, we need to further study the cytokine's expression in Radix Astragali aqua-acupuncture stimulation.

마늘재배의 생력기계화 시스템 모형

이규승,박원엽,신익환 성균관대학교 생명과학자원연구소 1996 生命資源科學硏究 Vol.3 No.1

Garlic is one of major vegetables and grown throughout the country of Korea. But the average farm size of garlic production is about 0.3ha and most of the farming operation for garlic production are done by human labour. There are more than ten operation steps for garlic production but only two steps are mechanized, or land preparation and polyethylene covering. Thus production cost is very high and the price of garlic is about 2 to 4 times higher compared with that of international marketing price. We evaluated present production system and problems of garlic production, and suggest mechanized garlic production system for lowering the production cost of garlic.

플라우의 경운저항 예측 관련 국내 논 토양의 물리적특성

이규승,박원엽,권병기 성균관대학교 생명과학자원연구소 1996 生命資源科學硏究 Vol.3 No.2

Two dimensional and three dimensional model for an inclined blade was evaluated to decide the soil physical properties which is necessary for draft prediction of moldboard plow. From the above model, soil cohesion, soil internal friction, soil-metal friction, soil-metal adhesion and bulk density were decided as soil parameters which are needed for computer simulation. Besides above soil parameters, soil moisture content and soil texture were measured for more information at the Iri, Namyang, Yeoju, Pyeongtaek, Asan, Suwon, Chungju, Milyang, Kimhae, Sangju, Kimpo and Kanghwa area from October to November and from March to May, from 1995 to 1996. The most popular soil texture was silty loam and loam The range of soil bulk density was 1500∼1700 kg/㎥. The range of soil cohesion was 10∼15 kPa and that of internal friction angle was 40∼60 degree. The range of soil-metal friction coefficient and adhesion was 0.3∼0.8 and 1.0∼3.0 kPa.

농기계의 보관 관리 실태에 관한 연구

이규승,김성엽,박원엽 성균관대학교 생명공학연구소 2001 生命工學硏究 Vol.7 No.1

This study was conducted to analyze the storage and management status of major farm machinery, and to present the basic information for the construction of multipurpose storage housing suitable to the individual farmers by identifying current problems. The average farm area of the surveyed farmers was 4.25ha, which represents relatively higher than the average of whole country. The mechanization rate for paddy farming was 98%. so, the individual storage housing should be concentrated on the farm machinery utilized in paddy farming. The annual operating time for the seasonal farm machinery(such as combine and rice transplanter) were showed high difference between farmers and machines. For the rice transplanter, the highest portion of annual operation time was 1∼10 days as 71%, and for the combine, that was over 20 days as 36% and the second was 16∼20 days as 23%. The average difference in repairing cost for combine between the farmers with and without common storage housing was 100,000 won. The percent of storaging farm machinery in the open field for farmers without housing were 44% for power tiller, 16% for farm tractor, 21% for rice transplanter, 10% for combine. Each farmer had the individual temporary simple housing with various kinds and structure. Most of the farmers, 63.7%, want to use the farm machinery storage housing as multipurpose utilization. Twenty nine percent of farmers want to use the farm machinery storage housing any for storaging purpose. And, most farmers prefer near the farm house as suitable position of housing, and prefer the area of 132∼198㎡ for storage housing. The current problems on common storage housing were insufficient area(44.8%), no problem(29%) improper position, excessive construction cost, inconvenient entrance, etc.

有限要素法에 의한 垂直荷重下의 타이어 變形 및 應力解析

하성호,이규승,박원엽 성균관대학교 생명과학자원연구소 1996 生命資源科學硏究 Vol.2 No.2

Tires are made of rubber composites which consist of several plies. Each ply consists of a thin layer of rubber matrix reinforced with unidirectional steel or polyester cords. The deformation and stress analysis of reinforced tires is very difficult because of the material properties and complexity of tire composites. In the present work, the tire inflation and contact problem has been solved by the finite element method in which overcome the complexity of tire composites. The finite element formulation is derived from the equilibrium equations by the principle of virtual work, and the constitutive equation given by the rubber material characteristics. Also, a contact formulation is added to the finite element formulation to calculate the stress distribution of tires in contact with flat rigid road under the vertical load. The calculation for the deformed shape and the stress distribution is executed by dividing into many time steps for incremental analysis. And the solutions of each time step are converged by modified Newton-Raphson iteration method. The results of the finite element analysis of the tire deformation and stress distribution, show good agreement with previous similar analysis of others.

Prediction of Tractive Performance of Tracked Vehicles Using a Computer Simulation Model

Park, Won Yeop,Chang, Young Chang,Lee, Kyou Seung 한국농업기계학회 2003 Agricultural and Biosystems Engineering Vol.4 No.1

A mathematical model was developed for estimating the mechanical interrelation between characteristics of soil and main design factors of a tracked vehicle, and predicting the tractive performance of the tracked vehicle. Based on the mathematical model, a computer simulation program(TPPMTV) was developed in the study. The model considered the continuous change in tension for the whole track of a tracked vehicle, the analysis of shape and tension of the track segment between sprocket and first roadwheel, and the side thrust on both sides of grouser by the active earth pressure theory in predicting the tractive performance of a tracked vehicle. Also, the model contained not only sinkage depth of the track but the pressure distribution under the track in analyzing the side thrust. The effectiveness of the developed model was verified by performing the drawbar pull tests with a tracked vehicle reconstructed for test in loam soil with moisture content of 18.92%. The predicted drawbar pulls by the model were well matched to the measured ones. Such results implied that the model developed in the study could estimate the drawbar pulls well at various soil conditions, and would be very useful as a simulation tool for designing a tracked vehicle and predicting its tractive performance.