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Thi Phuong Diu TRAN(Thi Phuong Diu TRAN ),Thi Van Khanh NGUYEN(Thi Van Khanh NGUYEN ),Thanh Quang DO3(Thanh Quang DO3 ),Cong Nghiep NGUYEN(Cong Nghiep NGUYEN ),Thu Thuy LUONG(Thu Thuy LUONG ) 한국유통과학회 2022 유통과학연구 Vol.20 No.10
Purpose: This article focuses on exploring the associations between job satisfaction, organizational commitment, and turnover intention. Specifically, this study estimates the impacts of Vietnamese employees’ job satisfaction on their organizational commitment and turnover intention in FDI enterprises. Research design, data and methodology: The measures are adapted from previous studies to develop a questionnaire with a seven-point Likert scale. The dataset is directly collected from 227 respondents who are employees at FDI enterprises situated in the North of Vietnam. The dataset is analyzed by quantitative approaches using SPSS 24.0 and AMOS 24.0. Results: The results show that while turnover intention is positively correlated with monthly income, it is negatively correlated with job satisfaction and organizational commitment. Also, organizational commitment is positively associated with job satisfaction among employees at FDI enterprises in Vietnam. Conclusions: The findings of this study will serve as useful references for administrators of FDI enterprises and policymakers to promote employees’ job satisfaction and retain skilled employees.
한국어 학습 환경에 따른 듣기 불안 및 듣기 전략 사용 양상 연구 -베트남 대학 학습자와 국내 한국어교육기관 학습자의 차이를 중심으로-
( Tran Thi Thu Phuong ),정혜선 ( Hyeseon Jeong ) 이중언어학회 2018 이중언어학 Vol.73 No.-
This study examins listening anxiety and listening strategy use of Vietnam Learners, who have studied Korean at Universities in Vietnam and at language institutes in Korea. The study was designed to see if there are any significant differences between learners in KSL and KFL background. Moreover, the study aims to examine correlations between listening anxiety and strategy use affected by learning environment. The results of this study are as follows. First, the listening anxiety of learners in Korea was somewhat lower than that of learners in Vietnam, and the difference between the two groups were statistically significant in the data of total anxiety of listening and the anxiety of input. Second, learners in Korea used more diverse strategies than learners in Vietnam, and this was also statistically significant. The cognitive strategies of both groups were high in preference strategies. Third, in the case of learners in Korea, all strategies except the meta-cognitive strategy showed a negative correlation with anxiety, whereas the learners in Vietnam only showed negative correlation in the higher meta-cognitive and effective strategies. (Ewha Womans University)
Phuong Tran,Thu Nhan Nguyen,Yeseul Lee,Phan Nhan Tran,Jeong-Sook Park 대한생리학회-대한약리학회 2021 The Korean Journal of Physiology & Pharmacology Vol.25 No.5
This study aimed to develop docetaxel (DTX) loaded poly(lactic-coglycolic acid) (PLGA) nanoparticles (DTX-NPs) and to evaluate the different pharmacological sensitivity of NPs to MCF-7 and MDA-MB-231 breast cancer cells. NPs containing DTX or coumarin-6 were prepared by the nanoprecipitation method using PLGA as a polymer and d-α-tocopherol polyethylene glycol 1000 succinate (TPGS) as a surfactant. The physicochemical properties of NPs were characterized. In vitro anticancer effect and cellular uptake were evaluated in breast cancer cells. The particle size and zeta potential of the DTX-NPs were 160.5 ± 3.0 nm and –26.7 ± 0.46 mV, respectively. The encapsulation efficiency and drug loading were 81.3 ± 1.85% and 10.6 ± 0.24%, respectively. The in vitro release of DTX from the DTX-NPs was sustained at pH 7.4 containing 0.5% Tween 80. The viability of MDA-MB-231 and MCF-7 cells with DTX-NPs was 37.5 ± 0.5% and 30.3 ± 1.13%, respectively. The IC50 values of DTX-NPs were 3.92- and 6.75-fold lower than that of DTX for MDA-MB-231 cells and MCF-7 cells, respectively. The cellular uptake of coumarin-6-loaded PLGA-NPs in MCF-7 cells was significantly higher than that in MDA-MB-231 cells. The pharmacological sensitivity in breast cancer cells was higher on MCF-7 cells than on MDA-MB-231 cells. In conclusion, we successfully developed DTX-NPs that showed a great potential for the controlled release of DTX. DTX-NPs are an effective formulation for improving anticancer effect in breast cancer cells.
Characterization of Ag-Doped p-Type SnO Thin Films Prepared by DC Magnetron Sputtering
Pham, Hoai Phuong,Thuy, Thanh Giang Le,Tran, Quang Trung,Nguyen, Hoang Hung,My Hoa, Huynh Tran,Thi Thu, Hoang,Cuong, Tran Viet Hindawi Limited 2017 Journal of nanomaterials Vol.2017 No.-
<P>Crystalline structure and optoelectrical properties of silver-doped tin monoxide thin films with different dopant concentrations prepared by DC magnetron sputtering are investigated. The X-ray diffraction patterns reveal that the tetragonal SnO phase exhibits preferred orientations along (101) and (110) planes. Our results indicate that replacing Sn<SUP>2+</SUP> in the SnO lattice with Ag<SUP>+</SUP> ions produces smaller-sized crystallites, which may lead to enhanced carrier scattering at grain boundaries. This causes a deterioration in the carrier mobility, even though the carrier concentration improves by two orders of magnitude due to doping. In addition, the Ag-doped SnO thin films show a p-type semiconductor behavior, with a direct optical gap and decreasing transmittance with increasing Ag dopant concentration.</P>
Chien Minh Tran,Ngoc Thi‑Thanh Nguyen,Minh Hieu Ho,Vinh Khanh Doan,Khanh Loan Ly,Nhi Ngoc‑Thao Dang,Nam Minh‑Phuong Tran,Hoai Thi‑Thu Nguyen,Long Phuoc Truong,Thai Minh Do,Quyen Ngoc Tran,Hien Quoc Ng 한국섬유공학회 2023 Fibers and polymers Vol.24 No.1
In this study, we proposed a straightforward electrospun polycaprolactone (PCL) loaded with silver nanoparticles (SNPs)membrane fabrication process, in which SNPs were directly synthesized from silver nitrate (AgNO3) in PCL–acetone mixtureby gamma irradiation. The insolubility of AgNO3in PCL solution was solved using an auxiliary dimethyl sulfoxide solvent. As a physical approach, gamma rays readily converted silver ions into SNPs without the addition of harmful reductionagents, which reduced the cytotoxicity of the synthesized material. By avoiding some processes such as purification, solventremoval, or redispersion of SNPs, this method was more time-saving compared to other related studies. SNPs formation wasconfirmed by both UV–Visible spectrum (UV–Vis) and X-ray diffraction analysis. Scanning electron microscopy (SEM)revealed that the addition of SNPs significantly reduced the fiber diameter of PCL–Ag membranes compared to that of rawPCL. Uniform spherical-shaped SNPs incorporated in PCL fibers were observed under transmission electron microscopy(TEM). The tensile test showed that the electrospun PCL–Ag membranes exhibited good mechanical characteristics. Moistureeasily penetrated the porous microstructure of PCL–Ag, facilitating wound humidity regulation. Inductively coupledplasma-mass spectroscopy (ICP-MS) was employed to study the release profiles of SNPs at different time intervals. Overall,the PCL–Ag 500 ppm sample exerted excellent antibacterial activity against Pseudomonas aeruginosa and Staphylococcusaureus strains and low in vitro cytotoxicity.
TRAN, The Tuan,LE, Tuan Hiep,DO, Phuong Thu Thi,DO, Tho Thi Korea Distribution Science Association 2022 The Journal of Asian Finance, Economics and Busine Vol.9 No.10
Improving the quality of teaching staff in universities is an important goal of most universities. Therefore, it is necessary to evaluate the factors affecting the quality improvement of lecturers at universities. There are many factors affecting the improvement of this quality of human resources. This article uses the survey method to assess the factors affecting the improvement of the quality of lecturers in education and training institutions of the Ministry of Transport of Vietnam. Currently, the Ministry of Transport of Vietnam has 4 educational institutions. The research team has assessed the impact factors at these 4 facilities. The research team conducted a survey for faculty members of the Ministry of Transport. The result was 446 votes. The authors have performed factor evaluation by multivariate regression model. The influencing factors include Professional competence, the virtue of teaching staff, scientific research capacity, participating in building a democratic educational environment, Professional support policy, Instructor's income, and Information technology support. Research results show that most of the factors have a positive impact on improving the quality of lecturers. Based on the survey results, the authors also make policy suggestions to further improve the quality of teaching staff of the schools in the coming time.
Nanoparticles for dendritic cell-based immunotherapy
Tran, Tuan Hiep,Tran, Thi Thu Phuong,Nguyen, Hanh Thuy,Phung, Cao Dai,Jeong, Jee-Heon,Stenzel, Martina H.,Jin, Sung Giu,Yong, Chul Soon,Truong, Duy Hieu,Kim, Jong Oh Elsevier 2018 International journal of pharmaceutics Vol.542 No.1
<P><B>Abstract</B></P> <P>Crosstalk among immune cells has attracted considerable attention with the advent of immunotherapy as a novel therapeutic approach for challenging diseases, especially cancer, which is the leading cause of mortality worldwide. Dendritic cells—the key antigen-presenting cells—play a pivotal role in immunological response by presenting exogenous epitopes to T cells, which induces the self-defense mechanisms of the body. Furthermore, nanotechnology has provided promising ways for diagnosing and treating cancer in the last decade. The progress in nanoparticle drug carrier development, combined with enhanced understanding of the immune system, has enabled harnessing of anti-tumor immunity. This review focuses on the recent advances in nanotechnology that have improved the therapeutic efficacy of immunotherapies, with emphasis on dendritic cell physiology and its role in presenting antigens and eliciting therapeutic T cell response.</P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>
Tran Cong Phong,Le Thi Thu Phuong,Huynh Vinh Phuc,Pham Tuan Vinh 한국물리학회 2013 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.62 No.2
We investigate the influence of phonon confinement on the optically-detected electrophonon resonance (ODEPR) effect and ODEPR linewidth in rectangular quantum wires (RQW). The ODEPR conditions as functions of the wire’s size and the photon energy are also obtained. The splittings of ODEPR peaks caused by the confined phonon are discussed. The numerical result for a specific RQW shows that in the two cases of confined and bulk phonons, the linewidth decreases with increasing wire size and increases with increasing temperature. Furthermore, in the small range of the wire’s size (<i>L</i> ≤ 40 nm), phonon confinement plays an important role and cannot be neglected in reaching the ODEPR linewidth.
Tran, Tuan Hiep,Tran, Thi Thu Phuong,Truong, Duy Hieu,Nguyen, Hanh Thuy,Pham, Tung Thanh,Yong, Chul Soon,Kim, Jong Oh Elsevier Science B.V. Amsterdam 2019 ACTA BIOMATERIALIA Vol. No.
<P><B>Abstract</B></P> <P>The expression of Toll-like receptors (TLRs) on antigen presenting cells, especially dendritic cells, offers several sensitive mediators to trigger an adaptive immune response, which potentially can be exploited to detect and eliminate pathogenic objects. Consequently, numerous agonists that target TLRs are being used clinically either alone or in combination with other therapies to strengthen the immune system in the battle against cancer. This review summarizes the roles of TLRs in tumor biology, and focuses on relevant TLR-dependent antitumor pathways and the conjugation of TLR agonists as adjuvants to nano- and micro-particles for boosting responses leading to cancer suppression and eradication.</P> <P><B>Statement of Significance</B></P> <P>Toll-like receptors (TLRs), which express on antigen presenting cells, such as dendritic cells and macrophages, play an important role in sensing pathogenic agents and inducing adaptive immunity. As a result, several TLR agonists have been investigating as therapeutic agents individually or in combination with other treatment modalities for cancer treatment through boosting the immune system. This review aims to focus on the roles of TLRs in cancer and TLR-dependent antitumor pathways as well as the use of different nano- or micro-particles bearing TLR agonists for tumor inhibition and elimination.</P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>
Tran, Tuan Hiep,Nguyen, Hanh Thuy,Le, Nam Van,Tran, Thi Thu Phuong,Lee, Jong Seong,Ku, Sae Kwang,Choi, Han-Gon,Yong, Chul Soon,Kim, Jong Oh Elsevier 2017 International journal of pharmaceutics Vol.528 No.1
<P><B>Abstract</B></P> <P>Heterogeneity of cancer cells and drug resistance require multiple therapeutic approaches for comprehensive treatment. In this study, temperature-sensitive liposomes containing anti-cancer agent tanespimycin (17-AAG) and photosensitizer IR 820 were developed for combination of phototherapy and chemotherapy. The temperature-sensitive liposomes composed of DPPC, cholesterol, DSPE-PEG, 17-AAG, and IR 820 (LP-AI) at weight ratio of 35/15/3/2/2 were formulated as a thin film using extrusion and evaluated for particle size, morphology and drug release profile. Furthermore, the anticancer effect of combined therapy was examined <I>in vitro</I> and <I>in vivo</I> in SCC-7 and MCF-7 cell lines. As a result, LP-AI was prepared at particle size of 166.7±1.3nm, PDI of 0.153±0.012, and ζ-potential of −32.6±0.8mV. After NIR irradiation (660 and 808nm laser), LP-AI could generate heat and ROS and enhance drug release from nanoparticles which were useful to kill the cancer cells. These were confirmed by <I>in vitro</I> cytotoxicity as well as <I>in vivo</I> effective ablation of tumors. In conclusion, fast drug release and enhanced treatment efficacy of LP-AI indicate the potential of integrating photo- and chemotherapy for synergistic anti-cancer effects.</P> <P><B>Graphical abstract</B></P> <P>Temperature-sensitive liposomes containing anti-cancer agent tanespimycin and photosensitizer IR 820 (LP-AI).</P> <P>[DISPLAY OMISSION]</P>