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- 저자 : ( Stevent Sumantri ) (검색결과 2 건)
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( Stevent Sumantri ),( Siti Setiati ),( Esthika Dewiasty ),( Dyah Purnamasari ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
Background: Type 2 diabetes (T2DM) was characterised with insulin resistance and defi ciency, furthermore with advancing age the was also an increase in insulin resistance. Clinical studies has proven that insulin resistance and T2DM increase the incidence of frailty syndrome in the elderly. Oral antidiabetics metformin was associated with the inhibition of aging process. Eventhough, there was no data that showed the relationship of metformin therapy to frailty syndrome. Methods: This was a case control study conducted in subjects =60 years old who visited the Geriatrics and Diabetes outpatient clinic of Cipto Mangunkusumo National Referral Hospital between March and June 2013. Diagnosis of frailty was established using the fi-40 item criteria. Statistical analysis was done with SPSS 20. 0, where chisquare method was used in bivariate and logistic regression method in multivariate analysis. Results: Frailty syndrome was found in 25% of subjects (n=59), with median age of 72 years old (SD 6. 27) and median of fi-40 item score was 0. 18 (SD 0. 085). Metformin was found to have a signifi cant relationship with frailty syndrome in the elderly diabetics, which retained signifi cant value after multivariate analysis (adjusted OR 0. 043; 95% CI 0. 019-0. 099; p<0. 001). Conclusions: Metformin was associated with independently lower risk of frailty syndrome in elderly diabetics.
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( Andree Kurniawan ),( Theo Audi Yanto ),( Nata Pratama Hardjo Lugito ),( Resa Setiadinata ),( Margaret Merlyn Tjiang ),( Indra Wijaya ),( Stevent Sumantri ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
Background: Obesity is an important risk factor for prehypertension and hypertension, and there are sex-specifi c differences in prevalence of obesity and hypertension. There is limited data about prehypertension in young adult in Indonesia. The aim of this study was to determine whether obesity has relationships with prehypertension and hypertension. Methods: The participants were Indonesian medical students aged 18-25 years. Subjects were classifi ed into three blood pressure (BP) groups; normotensive (BP below or equal to 120/80 mmHg), pre-hypertensive (BP between 120/80 mmHg to 140/90 mmHg) and hypertensive (BP above 140/90 mmHg). Obesity was evaluated by BMI above 25 kg/m2. Association of blood pressure in obese medical students was measured by using odds ratio (OR). Results: Eighty nine Indonesian medical students aged 18-25 years participated in the study. Twenty seven percent students were obese. There were 84.3% normotensive, 11.2% pre-hypertensive and 4.5% hypertensive students. Odds ratio of prehypertension and hypertension compared with normotension in obese students was 7.200 (p <0.000; 95% CI [2.103 - 24.656]). Conclusion: Obesity is associated with prehypertension and hypertension in Indonesian medical student. Key words: obesity, prehypertension, medical students
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