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( Sami Ullah Khan ),( Muhammad Arshad ),( Tahair Rasham ),( Abdullah Shoaib ) 호남수학회 2017 호남수학학술지 Vol.39 No.2
The objective of this manuscript is to continue the study of fixed point theory in dislocated metric spaces, introduced by Hitzler et al. [12]. Concretely, we apply the concept of dislocated metric spaces and obtain theorems asserting the existence of common fixed points for a pair of mappings satisfying new generalized rational contractions in such spaces.
Khan, Sami Ullah,Arshad, Muhammad,Rasham, Tahair,Shoaib, Abdullah The Honam Mathematical Society 2017 호남수학학술지 Vol.39 No.2
The objective of this manuscript is to continue the study of fixed point theory in dislocated metric spaces, introduced by Hitzler et al. [12]. Concretely, we apply the concept of dislocated metric spaces and obtain theorems asserting the existence of common fixed points for a pair of mappings satisfying new generalized rational contractions in such spaces.
Khan, Sami Ullah,Mahjabeen, Ishrat,Malik, Faraz Arshad,Kayani, Mahmood Akhtar Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.18
Glutathione is a thiol compound that plays an important role in the antioxidant defense system of the cell and its deficiency leads to an increased susceptibility to oxidative stress and, thus, progression of many disease states including head and neck cancer. In the present study, alterations of glutathione levels were investigated in study cohort of 500 samples (cohort 1 containing 200 head and neck cancer blood samples along with 200 healthy controls and cohort II with 50 head and neck squamous cell carcinoma tissue samples along with 50 control tissues) by high performance liquid chromatography. The results indicated that mean blood glutathione levels were significantly reduced in head and neck cancer patients (p<0.001) compared to respective controls. In contrast, the levels of glutathione total (p<0.05) and glutathione reduced (p<0.05) were significantly elevated in head and neck squamous cell carcinoma tissues compared to the adjacent cancer-free control tissues. In addition to this, pearson correlation performed to correlate different tissue glutathione levels (GSH) with clinical/pathological parameters demonstrated a significant negative correlation between pT-stage and GSH level ($r=-0.263^{**}$; p<0.01), C-stage and GSH level ($r=-0.335^{**}$; p<0.01), grade and GSH ($r=-0.329^{**}$; p<0.01) and grade versus redox index ($r=-0.213^{**}$; p<0.01) in HNSCC tissues. Our study suggests that dysregulation of glutathione levels in head and neck cancer has the potential to predict metastasis, and may serve as a prognostic marker.
Sohail A. Khan,M. Ijaz Khan,Sami Ullah Khan,M. Y. Malik,A. Ghareeb 한국자기학회 2021 Journal of Magnetics Vol.26 No.3
The theme of this article is to investigate hydrodynamic flow of an incompressible second grade nanoliquid by a curved stretched sheet. Energy expression is developed through dissipation and Joule heating. Brownian and thermophoresis diffusion are also scrutinized. Physical feature of entropy generation is discussed. Isothermal cubic autocatalytic chemical reactions are discussed. Suitable transformations are used to develop the ordinary differential system. To develop a convergent series solution we employed the Optimal Homotopy Analysis Technique (OHAM). Graphical description of velocity, entropy generation, temperature distribution and concentration versus sundry parameters are discussed. An opposite behavior in velocity field is noted for magnetic and curvature parameters. Temperature distribution and velocity field have reverse trends for melting parameter. An augmentation in temperature is observed for radiation parameter. Larger magnetic variable lead to improve the entropy generation. Entropy optimization is boosted versus higher magnetic parameter.
Magnetic Characteristics of Biological Fluid in Nonlinear Thermally Radiated Blood Flow
Bilal Ahmed,Sami Ullah Khan,M. Ijaz Khan,Soumaya Gouadria,Abdul H. Hamid,Mehreen Yousaf,M. Y. Malik 한국자기학회 2022 Journal of Magnetics Vol.27 No.1
The numerical solution of the flow non-Newtonian fluid induced by stretching sheet in the region of oblique stagnation point flow under inducement of externally applied uniform magnetic field orthogonal to the flow is presented. The analysis is made under the assumption of boundary layer which arrives to the system of partial differential equations which are then transformed to ordinary differential equations by using appropriate similarity transformations. The numerical solution of the modeled system of equation is obtained by parallel shooting technique and presented for different variations of involved parameters. It is noted that enhancement in magnetic field results in decrease in horizontal velocity and boundary layer becomes thinner. The obtained results are compared with the available results in the literature and found in excellent agreement in the limiting cases.
Tasawar Abbas,Kaouther Ghachem,Sami Ullah Khan,Bilal Ahmad,Muapper Alhadri,Lioua Kolsi 한국자기학회 2023 Journal of Magnetics Vol.28 No.1
The fluid flow under the slip effects present many dynamical applications in petroleum engineering, soil sciences, aerodynamics, thermal systems etc. The aim of current investigation is to observe the heat transfer phenomenon in magnetized flow of viscous fluid due channel with lower unbend wall. The fluid flow is altered due to interaction of slip effects. The injection phenomenon for porous medium has been considered. For heat transfer investigation, viscous dissipation applications are endorsed. The fundamental problem is modelled with associated laws. The variational iteration method (VIM) scheme is proposed to simulate the analytical outcomes. The numerical results for Nusselt number and skin friction coefficient are depicted and analysed graphically. The summarized observations convey that control of heat transfer is improved with interaction of slip phenomenon. The declining result for Nusselt number is referred to suction parameter.
Ali Raza Gurmani,Sami Ullah Khan,Amjad Ali,Tehseen Rubab,Timothy Schwinghamer,Ghulam Jilani,Abid Farid,Jinlin Zhang 한국원예학회 2018 Horticulture, Environment, and Biotechnology Vol.59 No.4
Greenhouse studies were undertaken to evaluate the genetic performance of two cucumber genotypes (Long Green and Summer Green) at four salinity levels (0, 25, 50, and 100 mM NaCl). Seeds were pretreated with 50 mg salicylic acid (SA) L−1 and 25 mg kinetin (Kin) L−1. Under hydroponic conditions, seed pretreatment with Kin significantly increased shoot and root dry biomass and reduced the salt injury index in both genotypes. SA reduced the salt injury index of Long Green cucumbers. In a pot experiment, Kin treatment reduced Na+ and increased K+ concentration, photosynthesis, and chlorophyll content in both genotypes, compared to SA under saline soil conditions. Kin treatment improved fruit yield in both genotypes, while SA had a statistically significant effect on Long Green fruit yield. The application of SA and Kin enhanced salinity tolerance in both genotypes by the activation of antioxidants, especially superoxide dismutase, peroxidase, and catalase, which offset oxidative injury. Summer Green exhibited better salt tolerance and improved osmoregulation that resulted in higher fruit yield than Long Green. It was concluded that cucumber genotypes differed in salt tolerance, and seed pre-treatment with Kin minimized salt stress injury, even in sensitive genotype which could sustain crop production under saline conditions.
Jalal Ud Din,Sami Ullah Khan,Ahmad Khan,Abdul Qayyum,Kashif Sarfraz Abbasi,Matthew A Jenks 한국원예학회 2015 Horticulture, Environment, and Biotechnology Vol.56 No.6
A few degrees in temperature above the optimum can cause a considerable yield loss in tomatoes. A research experiment was conducted in which three tomato genotypes of (Solanum lycopersicum Mill.), ‘Suncherry Extra Sweet’ (Suncherry), ‘Walter’, and ‘CLN-2498d’, were evaluated for response to moderate high temperature at the reproductive stage. High temperature reduced the total number of fruits per plant, fruit size, number of seeds per fruit, seed setting, and relative ovule viability. However, high temperature increased proline accumulation and membrane thermo-stability in plant parts of the investigated genotypes. Fruit size and the number of seeds per fruit were reduced in all the genotypes, with the greatest reduction occurring in Suncherry. Similarly, viability of male and female gametes was also reduced in all of the investigated genotypes due to high temperature injury. The reduction in seed setting due to high temperature was greatest in ‘Suncherry’ and ‘Walter’, and least in ‘CLN-2498d’. Likewise, ovule viability was least reduced in ‘CLN-2498d’. The genotypes accumulating higher proline concentrations in reproductive parts and with enhanced membrane thermo-stability under high temperature likewise produced the highest fruit yield, and hence, exhibited high temperature tolerance.
Hua Bian,Shah Faisal,Khan M Ijaz,El-Zahar Essam Roshdy,Farooq Shahid,Khan Sami Ullah,Guedri Kamel,Wu Wen-jing 한국CDE학회 2022 Journal of computational design and engineering Vol.9 No.3
The current investigation is concerned with the rheological impact of fourth-grade confined by Riga surface. The flow behaviour is analysed over a Riga plate in the presence of stagnation point and porous medium. The relevant similarity variables and corresponding boundary conditions are adopted to model the current problem. The highly non-linear coupled differential system is via optimal homotopy scheme. The outcomes of relevant dimensionless parameters on the velocity profile have been visualized with physical exploration. It is observed from the obtained outcomes that the fluid velocity declines against rising estimations of modified magnetic variable and inverse Darcy number. The increasing velocity change is noted for boosting values of third-grade fluid parameter. Moreover, the velocity pattern for fourth-grade material is comparatively higher than viscous, second-grade, and third-grade materials. The comparative analysis against obtained simulations is also listed.
Ali, Gowhar,Subhan, Fazal,Islam, Nazar Ul,Ullah, Nasir,Shahid, Muhammad,Ullah, Sami,Ullah, Ihsan,Shah, Rehmat,Khan, Ikhtiar,Sewell, Robert D. E.,Abbas, Ghulam 대한약학회 2014 Archives of Pharmacal Research Vol.37 No.7
The aim of the current study was to explore in vivo any relative gastroulcerogenic prospective propensity of newly synthesized nitrogen containing derivatives of salicyl alcohol; compound (I) [1-(2-hydroxybenzyl) piperidinium chloride], compound (II) [4-carbamoyl-1-(2- hydroxybenzyl)piperidinium chloride] and aspirin in albino rats. The experimental groups received the following oral treatments daily for 6 days: group I saline control; group II, standard (aspirin) treatment group [150 mg/kg of body weight]; group III, test (compound I) treatment group [100, 150 mg/kg]; group IV, test (compound II) treatment group [100, 150 mg/kg]. The results showed that in the case of the aspirin treated group and compound (I) [150 mg/kg], there was a significant increase in gastric volume, free acidity, total acidity, ulcer score and a decrease in gastric pH. Furthermore, histopathological examination of gastric mucosa of these treated groups revealed detectable morphological changes. Utilizing the same protocol, synthetic compound (I) [100 mg/kg] and (II) [100, 150 mg/kg] exhibited no statistically significant ulcerogenic or cytotoxic properties. A cyclooxygenase (COX) selectivity test indicated the preferential inhibition of COX-I and COX-II enzymes by compounds (I) and (II). This study therefore indicates that these synthetic compounds may possess reduced ulcerogenic potential and could be a functional substitute to aspirin.