응급실에서 succinylcholine을 이용한 기관내 삽관시 혈청 칼륨의 변화

김무수,최옥경,어은경,정구영 大韓應急醫學會 1997 대한응급의학회지 Vol.8 No.1

Succinylcholine is a depolarizing neuromuscular blocking agent(NMB) and is used in induction of anesthesia. Succinylcholine-assisted endotracheal intubation has been routinely used in the operating room and rapid sequence intubation with NMB agent has been the method for airway management in emergency department(ED). Adverse effects of succinylcholine are hyperkalemia, malignant hyperthermia, transient hypotension, arrhythmia, and increased intracranial, intraocular and gastric pressure, etc. This study carried out the change of serum potassium as an adverse effects of succinylcholine during endotracheal intubation in ED. A prospective, noncontrolled design was used to study serial serum potassium levels in pre-and postendotracheal intubation(5min) from February 1996 to August 1996. Succinycholine was selectively used in patient with a ploblem of difficult endotracheal intubation (alert to drowsy mental status with intact gag reflex). The dose of succinylcholine was 1.5 mg/kg and injected into intravenous line during preoxygenation with bag-valve-mask device. Student's two-tailed t-test was used and p-value was<0.05. Among the total of 48 patients(male 27, female 21), the postintubation level of the serum potassium of 25 patients were increased and those of 21 persons were decreased compared with preintubation level. Two patient showed no change in amount. The average serum potassium indicated 3.7±0.8 mEq/L before the injection of the succinylcholine and 3.8±0.9 mEq/L 5 minutes after its injection. P-value showed more than 0.05 and as the result statistically there was no noteworthy difference. All patients were intubated within 30 sec and no patients were failed. We concluded that succinylcholine-assisted endotracheal intubation is a rapid and safe method as an endotracheal intubation practiced in ED and succinylcholin-induced hyperkalemia is miniimal and no adverse effect.

생활치아의 Dentin Bonding에 따른 상아질내 미세구조 변화 및 치수반응

김옥경 大韓小兒齒科學會 1993 大韓小兒齒科學會誌 Vol.20 No.1

Since Buonocore developed acid etching to enamel in 1955, resin has been widely used reluctantly in may area of dental practic. Acid etching to dentin also has developed since 1977,yet,there are many controversies on dentin bonding agents reaction to dentin comprised of high organic and water content and on its pulp response. This study is to evaluate the microscopic structural change and histologic pulp response using 3 newly developed DBAs(Clearfil photobond,Prisma Univ. Bond 2, All bond 2),after cavity preparetion on 60 human premolars scheduled for extractions. The results and the conclusion are as follows: 1.Scanning electron microscopic views on resin tag penetration,hybrid layer formation were similar among materials used. 2.Dentin bonding agents penetrated to dentinal tubules forming resin tags either in smear layer removal groups or modifying groups. 3.Hybrid layer was formed widly in all material groups. 4.Under the cut dentimal tubules,slight pulp response were noted,but the area of rihgt under the cut dentinal tubules,the pulp response were normal. 5.Pulp response of acid pretreatment to dontin was normal,but Prisma Univ. Bond 2 group showed severe vacuole formation.

기업의 텔레마케팅 운영 현황과 문제점 및 개선 방안에 관한 연구

김영숙,이경옥 경성대학교 2000 論文集 Vol.21 No.2

In an information-oriented society consumers take account of not only the quality of goods but also the accompanying service. To follow the trend of the times telemarketing is indispensable. This thesis consists of the study of literature on telemarketing and the case study. The background, the concept and the general operating system of telemarketing are examined. In a case study, how to operate it in Pusan are analized. Last but not lest, suggestion the ways to operate telemarketing more efficiently and to activate it are also presented. Followings are suggested as solutions for would-be problems Enthusiastic and progressive concerns on the tele-marketing system implementation. And, total execution on the update and implementation of consumer information database. Finally, Professional counselors recruit and active measures or solution for trouble problems. With the complete execution of above, the perfect tele-marketing for consumer satisfaction management could be given to the public.

개선된 사람 혈장중 세파클러 농도 정량법을 이용한 세파클러 캡슐의 생체이용률 측정

김태완,송옥경,한선영,Cao, Qing-Ri,박미진,강성화,신관석,Cui, Jing-Hao,이범진 한국약제학회 2005 Journal of Pharmaceutical Investigation Vol.35 No.2

After establishing improved HPLC analytical method ofcefaclor in human plasma samples, a bioavailability study of cefaclor capsules was conducted according to the guidelines of Korea Food and Drug Administration (KFDA). The standard calibration curve using an HPLC with UV detector was constructed in a range of 0.0324--16 μg/m1. The 6% perchloric acid instead of 6% trichloroacetic acid was used to precipitate plasma protein. The HPLC chromatograms were precisely and accurately resolved when spiked with human plasma spiked with cefaclor and cephalexin (internal standard). Twenty healthy male Korean volunteers received two commercial cefaclor capsules, Neocef ' capsule (Jinyang Pharm. Co., Ltd) or Ceclor" capsule {Lilly Korea. Co., Ltd.) at the 250 mg cefaclor in a 2 x 2 crossover study. There was a one-week washout period between the doses. Plasma concentrations of cefaclor were monitored for 8 hours after oral drug administration. AUC, the area under the plasma concentration-time curve from time zero to 8 hr (13 points), was calculated by the linear trapezoidal rule method. C,,,a" (maximum plasma drug concentration) and Tmax (time to reach Cma,) were compiled from the plasma concentration-time data. Analysis of variance was carried out using logarithmically transformed AUC, and Cmax. No significant sequence effect was found for all of the bioavailability parameters indicating that the cross-over design was properly performed. The 90% confidence intervals of the AUC, ratio and the Cmax ratio for Neocer/Ceclor" were 0.9049 S S < 1.0304 and 0.9776 5 S 1.226, respectively. These values were within the acceptable bioequivalence intervals of 0.80-1.25. Thus, our study demonstrated the bioequivalence of Neocef"/Ceclor" with respect to the extent of absorption.

도플러검사법을 이용한 새로운 심기능평가법 : 급성 심근경색증에 의한 심기능장애의 선별진단법으로서 심기능지표의 유용성 The Utility of Cardiac Performance Index in the Screening Test of Cardiac Dysfunction due to Acute Myocardial Infarction

김원,임경수,이영주,최옥경,전정민 대한응급의학회 1999 대한응급의학회지 Vol.10 No.4

Background : Because systolic and diastolic dysfunction frequently coexist in acute myocardial infarction (AMI), we hypothesize that a combined measure of ventricular performance using Doppler echocardiography may be more sensitive and time-saving diagnostic tool for the evaluation of patients presenting with cardiogenic chest pain. Method and Results : Seventy-one patients with AMI (47 male, 59±11 years) and 45 patients with normal coronary artery (29 male, 52±11 years) were included in the study for measurement of cardiac performance index and established parameters of ventricular function using conventional echo-Doppler methods. a new derived index of cardiac performance: (ICT+IRT)/ET, was obtained by subtracting ejection time(ET) from the interval between cessation and onset of the mitral inflow velocity to give the sum of isovolumic contraction time(ICT) and isovolumic relaxation time(IRT). The mean value of the index was significantly different between normal and AMI(p<0.01). The degree of inter-group overlap was smaller for the index compared to other parameters. within functional groups, the value of the index did not appear to be related to heart rate, mean arterial pressure and the degree of mitral regurgitation. Conclusion : cardiac performance index is a conceptually new, simple and reproducible Doppler index of combined systolic and diastolic myocardial performance, and it is useful as screening test for patients with cardiac dysfunction due to AMI

한 3차 의료기관 병실의 환경위생상태에 관한 조사분석

김경남,옥치상 고신대학교 보건과학연구소 2000 보건과학연구소보 Vol.10 No.-

This study was to investigate the survey analysis on the environmental sanitation state within wards in a hospital by means of questionnaires and field measurement at summer and winter in 1998. The collected data were tested by ANOVA, correlative analysis and multiple regression analysis on the basis of the SPSS 7.5 package(window version). Based on the results, within wards the temperatures were 27.2℃ in summer, and 24.9℃ in winter, the moistures were 62.1% rh in summer and 26.4% rh in winter by mean. And the illuminations were 304lux in summer and 301lux in winter, the sound levels were 55.ldB in summer and 57.7dB in winter by mean. In addition, inpatients' recognition about temperatures, moistures, colors, sound levels and spaces were common in all in summer and winter. But the illuminations were somewhat higher than average in summer and winter. It is apparent that the physical, mental and sanitary environment factors have a great effect on the treatment and health care for the patients. So it is required more and more to improve and provide medical care services centering around patients. And it is necessary that the administrator be much interested in environmental quality factors to create comfortable and convenient ward environments.

서양 여성의 헤드드레스 변천에 관한 연구 : 고대부터 중세까지 from ancient times to the middle gaes

김경화,김태년,김경애,이승옥 우석대학교 자원개발연구소 1997 자원개발연구소논문집 Vol.2 No.-

Costume has expressed the life style and influence on natural and social environment, The purpose of this study is to understand changes of hair style and millinery life in the west. The data used in this study included in the literature on this subject. The research results can be summarized as follows. 1. A hair style of ancient times was frizz or chignon or dyed hair style. Sometimes, they wore wigs of false hair, or put on a head kerchief. Millinery has been not worn until then. 2. In the middle ages, the hat serve to symbolize the social rank or authority or religion. Turbans were worn which concealed the hair. The hair style were large stuffed rolls over which the wimple was sometimes draped. These stuffed rolls were also used to form some shapes of the hennin, principally the heart-shaped and circular cone style. The hennin was brought to France by Isabella of Bavaria in the latter part of the fourteenth century and its vogue lasted a hundred years. There were many styles of the hennin, invariably draped with a veil, floating or with wired edge. They became so extravagant in size that I found it necessary to regulate the height according to the socal position of the wearer.

관상동맥색전증에 의한 급성심근경색증 4예

김민근,주혜원,강경필,최병돈,박민석,변영섭,고충원,이건주,김병옥 인제대학교 2006 仁濟醫學 Vol.27 No.-

Acute myocardial infarction(AMI) due to coronary embolism can occur in patients with normal coronary artery. Coronary embolism is believed to be a cause of acute myocardial infarction when emergent coronary angiography shows perfectly normal coronary trees, except for the finding of coronary artery occlusion. In this report, we describe four patients with AMI due to coronary embolism who were successfully treated using a thrombus aspiration device and anticoagulation, and those patients had intracardial thrombus arising from the left atrium due to chronic atrial fibrillation and valvular heart disease. Patients with chronic or paroxysmal atrial fibrillation can present with AMI due to coronary embolism, and thrombus aspiration with percutaneous aspiration device is a feasible treatment option for these patients along with anticoagulation the rapy.

관상동맥 혈류의 예비력 측정에서 ATP(Adenosine Triphosphate)와 아데노이신의 비교

김원,탁승제,김한수,신준한,조윤경,최옥경,임경수,최병일 대한순환기학회 1998 Korean Circulation Journal Vol.28 No.6

RBL-2H3 세포에서 Spermine에 의한 히스타민 유리와 칼슘유입에 미치는 상백피의억제효과

채옥희,강경진,신인호,김영기,이무삼,전병득 대한해부학회 1994 Anatomy & Cell Biology Vol.27 No.2