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      • KCI등재후보

        The effect of process parameters on copper powder particle size and shape produced by electrolysis method

        Mustafa Boz,Masood Hasheminiasari 국제구조공학회 2013 Steel and Composite Structures, An International J Vol.15 No.2

        In this study, an electrolyzing device for the production of metal powders was designed and fabricated. The production of copper powders was performed using a variety of current densities, anode-cathode distances and power removal times. The effect of these parameters on powder particle size and shape was determined. Particle size was measured using a laser diffraction unit while the powder shape was determined by SEM. Experimental results show that an increase in current density leads to a decrease in powder particle size. In addition particle shape changed from globular dendritic to acicular dendritic with increasing the current density. Distance between the cathode and anode also showed a similar influence on powder particle size and shape. An increase in time of powder removal led to an increase in powder particle size, as the shape changed from acicular dendritic to globular dendritic.

      • Poster Session : PS 0123;Cardiology : Evaluation of the Microalbuminuria in Acute Coronary Syndrome Patients

        ( Suleyman Ahbab ),( Mustafa Boz ),( Ali Atay ),( Esra Atakoglu ),( Faik Oetin ),( Mustafa Yenigun ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

        Background: Atherosclerosis and endothelial dysfunction are main pathological event for developing ischemic heart disease. It is damaged that the endothelial produced vasoactive and antithrombotic agents in the process of atherosclerosis and endothelial dysfunction occurs. Microalbuminuria is an indicator for the endothelial dysfunction. In this study, it was investigated the relationship between microalbuminuria and acute coronary syndrome. Methods: This study was consisted up 35 acute coronary syndrome patients without diabetes mellitus. Metabolic parameters and microalbuminuria in 24 hours urinary collection of the patients were analyzed. Above 30 mg/dl daily urinary albumin excretion was described as microalbuminuria (30-300 mg/dl). Microalbuminuric patients were followed up for one year. Patients parameters` mean and standart deviation were calculated. It was statiscically meaningful, p<0,05. Results: 27 male and 8 female, total 35 patients were added in the study group. It was determinated that the mortality and reinfarctus were higher in microalbuminuric patient. 3 reinfarctus and 3 mortality were determinated in normoalbuminuric patients. Fasting triglycerid and homocystein levels were lower in microalbuminuric patients. Conclusions: It was demonstrated that the prognostic signifi cance of microalbuminuria in the acute coronary syndrome patients for one year follow up.

      • Poster Session : PS 0160 ; Diabetes : Qt Dispersion: Comparison Between Type 2 Diabetic with Microalbuminuria Positive and Negative Patients

        ( Esma Altunoglu ),( Mustafa Boz ),( Cuneyt Muderrisoglu ),( Fusun Erdenen ),( Ender Ulgen ),( Mustafa Duran ),( Nurcan Ozbas ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

        Background: It is shown that the variability of distance between QT derivations in twelve derivation ECG; is risk factor for sudden death as a predictor of cardiovascular mortality in both diabetic and general population. Diabetic nephropathy is one of the most common complication of diabetes. The purpose was to investigate the relationship between QT parameters and microalbumin/creatinine ratio; as an indicator of endothelial function and a cardiovascular risk factor. Methods: 100 patients were included our study who were follow up Istanbul Education and Research Hospital Diabetes Outpatient Clinic. 50 patients whose microalbumin/ creatinine ratio less than 30 mg/dl and ages between 36 and 77 years were chosen as control group; 50 patients whose microalbumin/ creatinine ratio between 30- 300 mg/dl and ages between 36 and 79 years were chosen as patient group. The QT interval was measured on the 12-lead resting ECG. QTd was calculated automatically using special software. Results: In patients group QTC min median value was higher; 380,63(361,44-397,30), (p=0,042),QTC max median value was significantly higher; 439,63(420,17-460,22), (p=0,005) and microalbumin/creatinine value 82(60-300), (p=0,0001) was very signifi cantly higher than control group. There was no signifi cant difference QTC dispersion median value 61,25(49,91-81,70, (p=0,066) in both groups. Also a good correlation in positive direction between QTC dispersion values and microalbumin/creatinine value was determined. Conclusions: We researched the relation between microalbumin/creatinine ratio and QTd levels in type 2 diabetic patients. QTc max period was determined signifi cantly high in the group with microalbumin/creatinine between 30-300 mg/dl (p<0,05). As a result of this correlation QT prolongation can be use as a contributory parameter for prediction of cardiovascular risk. This study make us that QTd can be used as early indicator of cardiovascular risk in diabetic patients who aren`t in microalbuminuric stage yet.

      • Slide Session : OS-END-03 ; Diabetes : Evaluation of Oral Glucose Tolerance Test in Hyperlipi-demic Normoglycemic Patients

        ( Feray Akbas ),( Hanife Usta Atmaca ),( Cigdem Alkac ),( Betul Borku Uysal ),( Burak Alkac ),( Mustafa Boz ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

        Background: Atherosclerotic coronary artery disease is an important health issue and a leading mortality reason in developed countries. In this study; we aimed to diagnose diabetes and other glucose disturbances early by evaluating the glycemic profile in hyperlipidemic patients and to decrease the cardiovascular morbidity and mortality by an early intervention. Methods: 46 female and 19 male, totally 65 hyperlipidemic normoglycemic patients were included in the study. Patients had no history of diabetes and normal fasting blood glucose levels and were diagnosed with hyperlipidemia during routine blood tests. There were no limitations for age, gender or body mass index. Coronary heart disease risk factors were questioned and findings were used to determine the pathological low density lipoprotein (LDL) levels. 2-hour oral glucose tolerance test (OGTT) was performed for all patients. Results were evaluated according to American Diabetes Association (ADA) 1997 criteria. Results: Mean total cholesterol level of patients was 236±41 mg/dl, mean trigliserid level was 223±141 mg/dl and mean LDL level was 153±38 mg/dl. According to OGTT results ; mean fasting blood glucose level was 95±13 mg/dl and mean 2nd hour glucose level was 128±34 mg/dl. According to ADA 97 criteria; OGTT of 33 (51%) patients were normal. 2 (3%) patients had impaired fasting glucose (IFG), 11 (17%) patients had impaired glucose tolerance (IGT) and 19 patients (29%) had diabetes. Conclusions: Hyperlipidemia and diabetes are important risk factors for cardiovascular disease and they usually coexist. Identification and early intervention of these risk factors are prognostically important. Thus; patients who are diagnosed with hyperlipidemia should be screened for glucose disturbances as a secondary risk factor and by early intervention of both risk factors, cardiovascular morbidity and mortality should be decreased.

      • Poster Session:PS 0491 ; Nephrology : Congenital Agenesis of the Inferior Vena Cava in a Presenting with Acute Renal Failure

        ( Hanife Usta Atmaca ),( Feray Akbas ),( Yesim Karagoz ),( Ebru Pekguc ),( Mustafa Boz ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

        Introduction: Agenesis of IVC (inferior vena cava) is a rare congenital anomaly which is generally incidentally found in asymptomatic patients. In patients with congenital intra-abdominal venous malformation, extreme care must be taken during radiological or surgical interventions. Case Report: A 35-year-old male patient was presented with nausea and vomiting following abdominal CT- performed for chronic abdominal pain-, presenting a subsequent decrease in urine output, and elevation of blood urea and creatinine. The patient had suffered from disseminated varicosities since the age of 15. In physical examination, intense subcutaneous venous collaterals on both lower extremities and abdomen and hepatosplenomegaly were observed. Grade 2 hydronephrosis in the right kidney and grade 4 hydronephrosis with decreased parenchymal thickness in the left kidney were present on renal ultrasonography. CT scan revealed discontinuity of contrast in the left portal vein compatible with portal vein thrombosis. On the left, ureteral continuity was not found. MR venography revealed an abnormally narrow IVC. The diagnosis was established as contrast induced nephropathy and the patient underwent hemodialysis. After 3 sessions, serum urea and creatinine levels, renal functions, and urine excretion returned to normal. The patient was discharged and a follow-up was planned. Discussion: Recognition of vascular abnormalities is important to prevent related complications. Agenesis of IVC enhances the risk of acute renal failure; regarding decreased renal fi ltration due to insuffi ciency of venous return and the mass effect on ureters, Extreme caution or even total abstinence for contrast media injection is necessary. Surgeons and interventional radiologists should be warned against potential complications.

      • Poster Session:PS 0200 ; Endocrinology : Can Microalbuminuria Predict Diastolic Dysfuncion in Metabolically Healthy Obese Patients?

        ( Feray Akbas ),( Hanife Usta Atmaca ),( Berrin Inal ),( Yasin Yuksel ),( Emin Piskinpasa ),( Mustafa Boz ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

        Background: Recent studies have shown that microalbuminuria (MAU) refl ected in a higher probability of cardiovascular disease for cardiovascular risk assessment. We aimed to question the availability of microalbuminuria in metabolically healthy obese patients as a predictor of diastolic dysfunction to assess the cardiovascular risk. Methods: 100 obese patients without accompanying diseases were included in the study. They were screened for any signs of acute/chronic inflammation and those having any were excluded. None of the patients were on any medications infl uencing diastolic dysfunction. Blood glucose, HbA1c, urea, creatinine, total cholesterol, LDL, HDL, triglyceride and 24-hour-urine microalbuminuria and creatinine clearance (GFR) levels were studied. Two-dimensional doppler echocardiography was performed. Data was statistically analyzed using SPSS Windows 11.5. Results: Statistical analysis showed that there was no signifi cant difference between patients with diastolic dysfunction and normal echocardiograpghy fi ndings when compared for MAU and also for BMI. In all groups, there was no relation between MAU and BMI according to correlation analysis. There was statistically significant difference for age (p<0,0001), glucose (p=0,019), total cholesterol (p=0,009) and LDL (p=0,019) and no difference for gender, smoking, HbA1c, HDL, systolic and diastolic blood pressure, creatinine, GFR and triglyceride (p>0,05) between groups. Conclusions: Microalbuminuria found in obese patients can be related with diastolic dysfunction which might refl ect subclinical cardiac damage with a simple method and in advance. The lack of demonstration of this relationship in our study might be due to limited number of patients included and especially low percentage of patients with microalbuminuria. But the relationship found for blood glucose and lipid parameters still can show metabolic tendency. If an approval of this relationship can be achieved by studies with a higher number of patients, an easy and non-invasive method to predict obesity cardiomyopathy might be possible.

      • Poster Session:PS 0535 ; Nephrology : Dialysis and Depression in the Light of Suicide Attempt with Fruits

        ( Feray Akbas ),( Hanife Usta Atmaca ),( Sennur Kose ),( Sevda Bag ),( Mustafa Boz ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

        Background: Depression is a co-morbidity whose identifi cation and intervention can be vital in chronic kidney failure. Case report: 36-year- old male patient was brought to ER with palpitation. He had been diagnosed with chronic kidney failure for 9 months and on dialysis for 6 months. Physical examination showed 220/minutes HR and ECG tachycardia with high T waves, broad QRS and P wave, prolonged PR distance which were consistent with severe hyperkalemia. His K level was 9.55 mEq/L and received an emergency dialysis. Control ECG was normal and K level was 4.86 mEq/L. The reason for fatal increase in K level was overconsumption of apricots. He didn`t follow his diet although warned at dialysis sessions. He was given education about his diet again. The following day, his K level was 7.48 mEq/L and received another emergency dialysis. He`d been eating grapes aware of the consequences. The patient was on dialysis in 3 months after his diagnosis and lost his job because of his dialysis sessions and was still unemployed. He had socioeconomical problems and learned that overconsumption of fruits could kill him. In the light of those fi ndings; he was considered to have major depression with suicidal ideation and was emergently referred to a psychiatry clinic for observation and treatment. Conclusion: Chronic kidney failure consists many physical and psychological problems. Dialysis patients depend on machines, invasive procedures and health workers, generally cannot keep a full time job. There is also a serious food and drink restriction. Thus; depression is common and there is a higher suicide rate. Still; depression is underdiagnosed and undertreated in dialysis patients. To check dialysis patients for depression signs and start therapy if needed will improve the quality of life and prevent possible suicide attempts.

      • Poster Session : PS 0396 ; Infectious Disease ; A Rarely Seen Empyema Cause: Leuconostoc Mesenteroides

        ( Hanife Usta Atmaca ),( Feray Akbas ),( Yesim Karagoz ),( Betul Borku Uysal ),( Mustafa Boz ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

        Case report: 64 year-old male patient was presented with cough, fever and sputum production. His medical history was unremarkable. He was producing and selling pickled vegetables. Only pathological fi nding in his physical examination was the reduction of pulmonary sounds in the lower part of left lung. Hemogram showed; leukocyte:5500/mm³ (neutrophil 65%, lymphocyte 30%), platelet: 287000/mm³, hematocrit 28%. Biochemical tests revealed normal, serum CRP level was 11,7 mg/dl. Pleural effusion was present in chest X-ray. Pleural ponction was performed. Gram-positive cocci and high concentration of leukocytes were seen in gram-staining in the exudative pleural fi uid. In the culture Leuconostoc mesenteroides was grown. CT showed pleural effusion and a consolidation containing air bronchogram. The patient was diagnosed with pleural empyema and drainage treatment with thorax tube and 2 grams of ceftriakson and 1 gr claritromycin daily were started. The symptoms regressed beginning from the fourth day. On the fourteenth day, CRP level returned to normal. The treatment was stopped at twenty-fi rst day with full recovery. Discussion: Leuconostocs are members of the family Streptococcacae and have only recently been recognized as potential pathogens. Infections by Leuconostoc species bacteria are uncommon, and usually affect patients with an underlying disease, or those fi tted with a venous catheter or subjects previously treated with vancomycin. Bacterias are found naturally in plants and vegetables and are used in milk, pickle and wine industries. While an underlying factor is needed for those organisms to become pathogenic, our case was completely healthy and had no invasive procedure previously. Because he was selling and directly producing pickles, it was considered that the organism could have passed directly. This case points out that; Leuconostoc mesenteroides should be considered as a causative agent in nasocomial infections, also in non- immunocompromised patients.

      • Poster Session : PS 0154 ; Diabetes : Do Diabetic Patients Use Their Glucometers Effectively: Awareness of the Importance of Self-Monitoring in Diabetes

        ( Feray Akbas ),( Hanife Usta Atmaca ),( Ilker Nihat Okten ),( Eda Nuhoglu ),( Mustafa Boz ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

        Background: Home glucose monitoring is vital for diabetic patients to maintain acceptable glucose levels. We aimed to demonstrate how effective home glucose monitoring was among diabetic patients who were followed in internal medicine outpatient clinics of our hospital. Methods: Randomly selected 89 diabetic patients who were admitted to internal medicine outpatient clinic in a week and who had glucometers were included in the study and a questionnaire was administered. The answers were categorized and the results were evaluated with SPSS. Results: The questions and the percentage of answers are shown in Table 1. Although diabetes duration of the patients was mostly more than 5 years, only half of them had a glucometer for that period. Most of the patients didn`t calibrate their devices. Most strikingly, only 25% of the patients in general were given a proper education for the usage of glucometers. 72% of patients who claimed to have been educated were mostly given instructions by a pharmacist that cannot be considered as education and only 35% of this group were educated by a diabetes nurse or a doctor. Only 40% of the patients monitored their glucose levels regularly, rest of the patients used their glucometers rarely or none. Conclusions: Home monitoring of glucose levels for diabetic patients would approve blood glucose levels by making necessary treatment adjustments available. Providing the optimal treatment would prevent/delay diabetes related complications, improve quality of life and contribute to decrease health costs. Thus; it`s necessary to educate and follow our diabetic patients better and assure that they use their glucometers more effectively and frequently. To include the patients to the treatment and to monitoring of diabetes seems to be the only way to achieve a better outcome of the disease.

      • Poster Session:PS 0186 ; Endocrinology : Neutrophil to Lymphocyte Ratio as an Infl ammatory Marker in Obesity

        ( Hanife Usta Atmaca ),( Feray Akbas ),( Ilker Nihat Okten ),( Eda Nuhoglu Kantarci ),( Berrin Belcik Inal ),( Mustafa Boz ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

        Background: Obesity is a disease known to stimulate low grade infl ammation. N/L ratio has been started to be used as an indicator of systemic infl ammation. This study aims to examine the relationship between obesity and N/L ratio over anthropometric measurements, obesity grade, and some biochemical parameters. Methods: 96 obese patients (mild-moderate and severe) who are being monitored in obesity outpatient clinic, who have no concomitant disease, and who do not have a history of smoking and drug use, and as the control group, 20 patients of normal weight with the same characteristics were included in the study. Anthropometric measurements were recorded, and BMI was calculated. Biochemical tests and total blood counts were performed. N/L ratio was obtained by dividing neutrophil count by lymphocyte count. The results were evaluated using SPSS statistical analysis program. Results: A signifi cant increase was present in neutrophils and lymphocyte counts of morbid obese group compared to control groups. Due to both increased neutrophil and lymphocyte counts, even though L/N ratio increased, it was not found statistically signifi cant. The increase in total leucocyte count of morbid obese was statistically signifi cant compared to mild obese. While N/L ratio demonstrated a strongly positive correlation with total leucocyte count and neutrophil count, it demonstrated a weakly positive correlation with waist circumference and with hip circumference. Conclusions: N/L ratio increases by obesity grade and reveals that concomitant infl ammatory response increases. High count of circulating neutrophil in obese patients might be considered as an acute infl ammatory response to a chronic infl ammatory state. Therefore, N/L ratio might be used as an infl ammatory marker in obese patients, and might be helpful in the prediction of cardiovascular and metabolic risks for the patient.

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