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Long working hours and cardiovascular disease: a meta-analysis of epidemiologic studies.
Kang, Mo-Yeol,Park, Hyunseung,Seo, Jeong-Cheol,Kim, Donghoon,Lim, Youn-Hee,Lim, Sinye,Cho, Soo-Hun,Hong, Yun-Chul Lippincott Williams & Wilkins 2012 Journal of Occupational and Environmental Medicine Vol.54 No.5
<P>To conduct a meta-analysis from published studies to evaluate the relationship between long working hours and the risk of cardiovascular disease (CVD).</P>
Increased risk of gastric cancer in workers with occupational dust exposure
( Mo-yeol Kang ),( Jiyoun Jung ),( Jung-wan Koo ),( Inah Kim ),( Hyoung-ryoul Kim ),( Jun-pyo Myong ) 대한내과학회 2021 The Korean Journal of Internal Medicine Vol.36 No.0
Background/Aims: Workers who are exposed to dust in the workplace tend to show a higher incidence of gastric cancer. Nevertheless, scientific evidence to support an association between dust exposure and the risk of gastric cancer is inadequate. This study aimed to investigate whether or not occupational dust exposure influences the risk of gastric cancer. Methods: We collected the electronic data from the Pneumoconiosis Health Examination (PHE) program, provided by the Ministry of Employment and Labor and the Korea Workers’ Compensation and Welfare Service from 2002 to 2017. The PHE database was linked to the National Health Insurances databases. The age-standardized incidence ratio (SIR) and 95% confidence intervals (CIs) of the risk of gastric cancers were evaluated in workers with occupational dust exposure, and the results were compared to those in the general population. Results: From 2004 to 2015, 1,543 cases of gastric cancer were observed in the male participants, as compared with 1,174 of expected cases, which yielded an SIR of 1.314 (95% CI, 1.249 to 1.380). Under dust exposure, the risk of gastric cancer was increased 23.9% in the male participants (95% CI, 19.9 to 27.5), and the degree of impairment of lung function was inversely related to the risk of gastric cancer. Conclusions: Workers with occupational dust exposure were at higher risk of developing gastric cancer than the general population. Thus, future efforts for the prevention of gastric cancer are necessary for dust exposed workers.
Heejoo Ko(Heejoo Ko),Dohwan Kim(Dohwan Kim),Seong-Sik Cho(Seong-Sik Cho),Mo-Yeol Kang(Mo-Yeol Kang) 한국역학회 2023 Epidemiology and Health Vol.45 No.-
OBJECTIVES: The physical activity paradox suggests that occupational physical activity (OPA), unlike leisure-time physical activity (LTPA), may detrimentally impact health. We explored the relationships of OPA and LTPA with work ability (WA) and health-related productivity loss (HRPL). METHODS: This study included 5,501 workers in Korea who were recruited in 2021 through a web-based cross-sectional questionnaire. The questionnaire was utilized to quantify OPA and LTPA in metabolic equivalents, while WA and HRPL were also measured. Non-parametric regression, using a generalized additive model (GAM), was employed to visualize the relationships of LTPA and OPA with WA and HRPL. Mean differences in WA and HRPL, in relation to OPA and LTPA, were examined using linear regression models. These models were adjusted for covariates including sex, age, body mass index, education level, alcohol consumption, smoking history, insomnia, occupation, hours worked, and income. RESULTS: The GAM and linear regression analyses revealed that higher LTPA corresponded with higher WA and lower HRPL. In contrast, as OPA increased, WA decreased and HRPL increased. However, within the group with high OPA, HRPL was not significantly lower in the high-LTPA subgroup relative to the low-LTPA subgroup (mean difference=1.92%, p=0.343). This pattern was especially pronounced among workers aged 60 years and older, with an increase in HRPL observed with increasing LTPA among the respondents with high OPA. CONCLUSIONS: High LTPA levels were associated with elevated WA and diminished HRPL. In contrast, higher levels of OPA were associated with lower WA and higher HRPL.
( Kang Mo Gu ),( Jong Wook Shin ),( Joo Young Lee ),( Jin Se Kim ),( Ju Young Jang ),( Jae Woo Jung ),( Jae Chol Choi ),( Jae Yeol Kim ),( In Won Park ),( Byung Whui Choi ) 대한결핵 및 호흡기학회 2014 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.118 No.-
Introduction: Histologic type of lung cancer has important roles for determining treatment strategies and patients’ prognosis. Immunohistochemistry may be used to verify neuroendocrine differentiation within tumor. Advanced non-small cell lung cancer with neuroendocrine differentiation is rare form of non-small cell lung cancer. In this report, we presents a case of advanced non-small cell lung cancer with neuroendocrine differentiation. Case: 64-year-old man was admitted to the hospital because of dyspepsia and weight loss (56kg->45.6kg) for one year. Physical examination showed non-specific findings. In laboratory finding, tumor marker was elevated (CEA 7.05U/ml, PIVKA II 501 mAUg/ml). The findings on abdominal imaging(Enhanced abdomen & pelvic CT and abdominal ultrasonography) showed multiple variable sized peripheral enhanced, hypervascular liver masses suggesting metastatic liver malignancy. Esophagogastroduodenoscopy and colonoscopy showed no abnormal lesion in stomach, duodenum and colon. For finding primary origin, enhance chest CT was done and 46mm mass lesion was detected in left upper lung and mediastinal lymph node metastasis were also detected. PET-CT showed higher fluorodeoxyglucose(FDG) uptake in left upper lung mass, liver masses and moderate uptake in left hilar lymph node, right ileum, right femur, left femur head. For pathologic confirm, CT-guided lung biopsy was done, poorly differentiated adenocarcinoma with neuroendocrine differentiation with a few positive for thyroid transcription factor-1(TTF-1), positive for CD56, negative for p63 was confirmed. Clinical staging was Stage IV(T2aN2M1b). The patient received palliative chemotherapy with gemcitabine with carboplatin(first line) and gefitinib with nimotuzumab(second line).