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( Youngshin Ju ),( Kyoungsuk Kwon ) 한국유아교육학회 2021 정기학술대회 논문집 Vol.2021 No.1
This study aimed to examine the general trends and relationships of early childhood teacher’s play teaching efficacy, teacher competency, and teacher-child interaction, as well as the effect of play teaching efficacy and teacher competency on teacher-child interaction. The subjects of this study were 280 early childhood teachers working at public and private kindergartens and various types of child care centers. Data were collected using surveys on teacher-child interaction, play teaching efficacy, and teacher competency. The results were as follows. First, play teaching efficacy, teacher competency, and teacher-child interaction of early childhood teacher showed high tendency. Second, play teaching efficacy, teacher competency, and teacher-child interaction of early childhood teacher showed significant correlations. Third, teacher competency had a significant influence on teacher-child interaction and the sub-factors. The belief in play teaching efficacy, which is a sub-factor of play teaching efficacy, and sub-factors of teacher competency, sensitivity, autonomy, professionalism, and stimulus provision were found to have a significant effect on teacher-child interaction.
PEMS를 이용한 대형차량 배출가스 측정 및 실시간 희석 요율 산출
맹성호(Sungho Maeng),이범호(Beomho Lee),주경석(Kyoungsuk Joo),이대엽(Daeyup Lee),박용희(Yonghee Park),권상일(Sangil Kwon),전상우(Sangwoo Jeon) 한국유체기계학회 2006 유체기계 연구개발 발표회 논문집 Vol.- No.-
Among the used vehicles, the number of heavy duty vehicles isnot so big, but the effect to environment is so high. So, it is very important to regulate emission and measure precisely in heavy duty vehicles. Chassis dynamometer for heavy duty vehicles which was introduced to the domestic research center in this year can measure exhaust emission of heavy duty vehicles(more than 3.5tons) at real road condition. Beside this measuring system has advantage forsaving time and cost. In spite of these advantages, it is impossible to adjust almost every(0.57million) used vehicles to the system. Therefore, research for measuring emission with PEMS(Portable On-board Emission Measurement System) which is portable and easy to equip, is on process. In this paper, we calculated Dilution Factor as well as analyzed density and total amount of emission to compare CVS(Constant volume sampler) system and PEMS through measured data from a same vehicle at the same time.
CoPPIX Protects against TNBS Induced Colitis Through HO-1 Induction
오재민(JaeMin Oh),김진오(JinOh Kim),권영미(Young-Mi Kwon),유민욱(MinWook Rheu),김유림(YuRim Kim),김경숙(KyoungSuk Kim),박승택(SeungTaeck Park),김정중(JeongJoong Kim),최민규(MinKyu Choi),정연태(YeunTai Chung) 대한해부학회 2004 Anatomy & Cell Biology Vol.37 No.5
크론병은 만성 염증성 대장 질환으로 면역반응을 억제함으로써 치료를 시도하고 있으나 치료가 쉽지 않고 치료하는 과정에서 많은 부작용이 생기는 질환이다. 따라서 부작용이 적은 새로운 약제의 개발이 절실한 실정이다. HO-1는 염증 반응을 억제하는 효과가 있다고 알려져 있으나 크론병에서의 그 작용기전은 거의 알려져 있지 않다. 따라서 우리는 크론병 동물모델인 TNBS에 의해 유도된 만성 대장염 모델에서 HO-1의 항 염증 기전을 조사하였다. HO-1의 유도제인 CoPPIX 는 생쥐에서 TNBS에 의한 체중감소, MPO 활성, NF-κB 활성 및 병리, 조직학적 증상 등을 현 저히 개선하였다. 또한 염증의 유지에 중요한 역할을 하는 TNF-α와 IL-1β 등의 발현 역시 억제하였다. 이러한 CoPPIX의 효과들은 HO-1 활성 억제제인 ZnPPIX에 의해 차단되었다. 이상의 결과로 CoPPIX는 HO-1의 유도를 통해서 TNBS에 의해 유도된 만성 대장염의 증상들을 개선시킬 수 있다고 생각되었다. 결론적으로 CoPPIX는 크론병의 치료에 있어 중요한 치료제가 될 수 있다고 생각하며 HO-1은 크론병의 치료에 중요한 target 물질이 될 수 있다고 생각한다. Crohn’s disease is a severe chronic inflammation that is treated mainly by immunosuppression, which often has serious side effects. There is a need to develop new drugs for treating this disease that have few side effects. Heme oxygenase-1 (HO-1) has immunosuppressive properties, but the mechanism of its anti-inflammatory actions is unclear. We investigated the protective effects of HO-1 on trinitrobenzene sulfonic acid (TNBS)-induced colitis in mice. An HO-1 inducer, cobalt protoporphyrin IX (CoPPIX), dramatically improved the clinical and histopathological symptoms in TNBS-induced colitis. CoPPIX suppressed tumor necrosis factor-α and interleukin-1β expression and down-regulated the nuclear transcription factor κB activity caused by TNBS. The vehicle copper protoporphyrin IX (CuPPIX) failed to duplicate the protective effects seen with CoPPIX. Moreover, an inhibitor of HO-1 activity-zinc protoporphyrin IX-reversed the protective effects of CoPPIX on TNBS-induced colitis. In conclusion CoPPIX protects against TNBS-induced colonic damage by inducing HO-1, which might be an important target in the treatment of Crohn’s disease.
Proton Conduction in a Tyrosine-Rich Peptide/Manganese Oxide Hybrid Nanofilm
Lee, Jaehun,Choe, Ik Rang,Kim, Young-O,Namgung, Seok Daniel,Jin, Kyoungsuk,Ahn, Hyo-Yong,Sung, Taehoon,Kwon, Jang-Yeon,Lee, Yoon-Sik,Nam, Ki Tae Wiley - VCH Verlag GmbH & Co. KGaA 2017 Advanced Functional Materials Vol.27 No.35
Tyrosine mediated 2D peptide assembly and its role as a bio-inspired catalytic scaffold
Ki Tae Nam,Yoon-Sik Lee,Hyung-Seok Jang,Jung-Ho Lee,Yong-Sun Park,Jimin Park,Tae-Youl Yang,Kyoungsuk Jin,Jae Hun Lee,Sunghak Park,Jae Muoyng You,Ki-Woong Jeong,Areum Shin,In-Seon Oh,Min-Kyung Kwon,Yon 한국고분자학회 2014 한국고분자학회 학술대회 연구논문 초록집 Vol.2014 No.4