매복치의 외과적 노출에 대한 임상적 연구

김지연,김재덕,백종성,손경준 조선대학교 구강생물학연구소 2002 口腔生物學硏究 Vol.26 No.2

Impaction and ectopic eruption of Permanent teeth can cause various clinical Problems. These teeth are not hopeless. It is possible to use the remaining teeth as anchorage, surgically uncover the impacted tooth, and orthodontically move the tooth into the arch. The specific surgical procedure and the orthodontic mechanics, however, will vary depending upon the type of tooth and its position relative to the remaining erupted teeth. There are different surgical techniques for the surgical exposure of the impacted teeth. These case reports described the surgical exposure using the apically positioned flap(APF) and closed eruption technique ,

분광 앨립소미트리를 이용한 유리기판 위의 박막 분석

성덕경,방경윤,오영륙,최은호,안일신,김옥경 한양대학교 이학기술연구소 2003 이학기술연구지 Vol.6 No.-

Spectroscopic ellipsometry 은 다양한 물질의 광학적 특징을 연구할 수 있는 강력한 기술이다. 현재 실리콘 웨이퍼 위의 박막 분석에는 그 효율성이 확실히 입증되어 있다. 그러나 현재 산업은 유리 기판위의 박막을 분석하기를 원하고 있다. Ellipsometry로 투명기판을 분석하기 위해서는 후면 반사에의한 비간섭성 효과를 고려해야 한다. 기존의 반사공식을 투명기판의 비간섭성을 고려하여 수정하였다. 투명기판 위의 샘플과 scratch를 낸 같은 샘플을 측정 분석하여 정확성을 확인하였다. 수정된 반사공식을 이용하면 디스플레이와 같은 투명재료를 이용하는 곳에 유용하게 사용될 것으로 기대되고 있다. A Spectroscpic ellipsometry is very strong technology to study optical properties of many materials. It has already substantiated a analytic efficiency about thin films above wafers to be made of silicon. However, the current industry needs thin films analyzed on a glass. When we analyze a glass using a ellipsometry, we have to consider a efficiency of incoherence due to reflect at the back side. So then, we slightly altered the original formula. We compared a scratched sample with a sample on the glass, because off getting a exactitude. Our technical development, using the changed formula, is expected the useful utilization in a part of using gIasses such as display.

염소를 포함한 액체에서의 금박막 패터닝과 표면 분석

성덕경,최정옥,안일신,김옥경 한양대학교 이학기술연구소 2004 이학기술연구지 Vol.7 No.

금박막은 높은 전도성의 화학적인 안정성을 가지고 있으므로 GaAs를 기판으로 한 bevice에서 널리 쓰이고 있으며 SAM(Self-Assembled Monolayer), Nanolithography 등에서도 아주 주요하게 사용되고 있다. 본 연구에서는 염소가 포함된 액체에 금박막이 접해있고 UV를 조사하여 식각이 되는 것을 발견하고 연구하였다. 노광량을 조절하여 금박막의 기각률을 조절할수 있으며, 또한 가모강제 공정을 거치지 않고 금박막에 직접 조사하게 되므로 간단하게 패터닝을 할수 있다. AFM(atomic force microscope), optical microscope, ellipsometry 를 이용하여 식각률 측정 및 표면 변화를 보았다. Various metals or their alloys are used in the semiconductor metallization process or in micro-or nano-structure devices. We report a novel etching technique of gold film based on new phenomenon that gold is soluble in chlorine containing solutions or solvents under UV irradiation. Mask patterns can be transferred to gold surface directly without resorting to complicate photoresist process. And, etch rate could be controlled from sub nanometer to few tens of nanometers per minute by adjusting exposure parameters. Moreover, non-toxic liquid such as NaCl solution can be used for the process. AFM(atomic force microscope), optical microscope, ellipsometry were used to characterize the etch rate and the surface morphology.

참깨박의 재활용방안 : 제2보, 알칼리 및 염수추출법에 의한 분리참깨단백의 제조 2. Manufacturing of Isolated Sesame Protein by Alkali and Salt Extraction Method

이근보,김경이,구본순,김덕숙 瑞逸專門大學 1993 論文集 Vol.11 No.-

참깨탈지박(DSM)으로부터 알칼리(AEM) 및 염수추출법(SEM)에 의하여 분리참깨단백(ISP)을 제조한 결과 회수율은 각각 43.06, 41.13%였으며, ISP의 조단백 함량은 각각 90.14, 91.08%였다. 현째까지 알려진 바로는 AEM이 가장 적합한 추출방법인 것으로 알려지고 있으나, 회수율 및 단백함량 등을 종합적으로 고려할 때, SEM이 우수한 것으로 밝혀졌다. 이들 ISP의 아미노산 조성은 필수 아미노산중 Isoleucine, Lysine이 FAO 권장치 이하였으며, Lysine 함량은 FAO 권장치의 57-64%에 그쳐 제한 아미노산으로 밝혀졌다. We are manufactured isolated sesame protein(ISP) from defatted sesame meal used for extraction method by alkali(AEM) and saline solution(SEM). The recovery yields were 43.06, 41.13%, and crude protein content of ISP were 90.14, 91.08%, respectively. AEM was reported the most suitable extraction method. But in the case of consideration the recovery yield and crude protein content, SEM was a excellent extraction method. Amino acid composition of ISP was represented the low level to isoleucine and lysine than FAO reference pattern. Expecially, lysine was a limiting amino acid, the content was about 57-64% level of FAO reference pattern.

Polymorphisms in DNA Repair Genes and <i>MDR1</i> and the Risk for Non-Hodgkin Lymphoma

Kim, Hee Nam,Kim, Nan Young,Yu, Li,Kim, Yeo-Kyeoung,Lee, Il-Kwon,Yang, Deok-Hwan,Lee, Je-Jung,Shin, Min-Ho,Park, Kyeong-Soo,Choi, Jin-Su,Kim, Hyeoung-Joon Molecular Diversity Preservation International (MD 2014 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Vol.15 No.4

<P>The damage caused by oxidative stress and exposure to cigarette smoke and alcohol necessitate DNA damage repair and transport by multidrug resistance-1 (MDR1). To explore the association between polymorphisms in these genes and non-Hodgkin lymphoma risk, we analyzed 15 polymorphisms of 12 genes in a population-based study in Korea (694 cases and 1700 controls). Four genotypes of DNA repair pathway genes (<I>XRCC1</I> 399 GA, <I>OGG1</I> 326 GG, <I>BRCA1</I> 871 TT, and <I>WRN</I> 787 TT) were associated with a decreased risk for NHL [odds ratio (<I>OR</I>)<SUB>XRCC1 GA</SUB> = 0.80, <I>p</I> = 0.02; <I>OR</I><SUB>OGG1 GG</SUB> = 0.70, <I>p</I> = 0.008; <I>OR</I><SUB>BRCA1 TT</SUB> = 0.71, <I>p</I> = 0.048; <I>OR</I><SUB>WRN TT</SUB> = 0.68, <I>p</I> = 0.01]. Conversely, the <I>MGMT</I> 115 CT genotype was associated with an increased risk for NHL (<I>OR</I> = 1.25, <I>p</I> = 0.04). In the <I>MDR1</I> gene, the 1236 CC genotype was associated with a decreased risk for NHL (<I>OR</I> = 0.74, <I>p</I> = 0.04), and the 3435 CT and TT genotypes were associated with an increased risk (<I>OR</I><SUB>3435CT</SUB> = 1.50, <I>p</I> < 0.0001; <I>OR</I><SUB>3435TT</SUB> = 1.43, <I>p</I> = 0.02). These results suggest that polymorphisms in the DNA repair genes <I>XRCC1</I>, <I>OGG1</I>, <I>BRCA1</I>, <I>WRN1</I>, and <I>MGMT</I> and in the <I>MDR1</I> gene may affect the risk for NHL in Korean patients.</P>

Two cases of duodenal ulcer perforation in the postpartum period several days after cesarean section

( Deok Gyeong Kim ),( Hui Gyeong Suh ),( Ji Won Min ),( Sun Kyeong Kim ),( Yun Sook Kim ),( Jong Eun Lee ) 대한산부인과학회 2018 대한산부인과학회 학술대회 Vol.104 No.-

Small bowel perforation in the postpartum period is very rare and is often misdiagnosed as functional paralytic ileus after surgery or pain at the wound, rapid and accurate diagnosis can be very difficult and delayed for various reasons, which can threaten the life of the mother. In the past 10 years, we have had experienced two cases of duodenal ulcer perforation after cesarean section. In all two cases, there was no past history of the ulcer, the first case was too severe and laparotomy after laparoscopic attempt was performed, and the second case was treated laparoscopic surgery by 3-0 V-LocTM absorbable wound closure device. In case of unexpected abdominal pain, especially in the case of accompanying fever during well recovery 4-7 days after cesarean section, if the surgical site is normal, the gastrointestinal disorder should be considered. Acknowledgements: This work was supported by the Soonchunhyang University Research Fund

The Use of Inappropriate Antibiotics in Patients Admitted to Intensive Care Units with Nursing Home-Acquired Pneumonia at a Korean Teaching Hospital

( Deok Hee Kim ),( Ha Jeong Kim ),( Hae-won Koo ),( Won Bae ),( So-hee Park ),( Hyeon-kyoung Koo ),( Hye Kyeong Park ),( Sung-soon Lee ),( Hyung Koo Kang ) 대한결핵 및 호흡기학회 2020 Tuberculosis and Respiratory Diseases Vol.83 No.1

Background: Use of appropriate antibiotics for the treatment of pneumonia is integral in patients admitted to intensive care units (ICUs). Although it is recommended that empirical treatment regimens should be based on the local distribution of pathogens in patients with suspected hospital-acquired pneumonia, few studies observe patients admitted to ICUs with nursing home-acquired pneumonia (NHAP). We found factors associated with the use of inappropriate antibiotics in patients with pneumonia admitted to the ICU via the emergency room (ER). Methods: We performed a retrospective cohort study of 83 pneumonia patients with confirmed causative bacteria admitted to ICUs via ER March 2015-May 2017. We compared clinical parameters, between patients who received appropriate or inappropriate antibiotics using the Mann-Whitney U, Pearson’s chi-square, and Fisher’s exact tests. We investigated independent factors associated with inappropriate antibiotic use in patients using multivariate logistic regression. Results: Among 83 patients, 30 patients (36.1%) received inappropriate antibiotics. NHAP patients were more frequently treated with inappropriate antibiotics than with appropriate antibiotics (47.2% vs. 96.7%, p<0.001). Methicillin-resistant Staphylococcus aureus was more frequently isolated from individuals in the inappropriate antibiotics-treated group than in the appropriate antibiotics-treated group (7.5% vs. 70.0%, p<0.001). In multivariate analysis, NHAP was independently associated with the use of inappropriate antibiotics in patients with pneumonia admitted to the ICU via ER. Conclusion: NHAP is a risk factor associated with the use of inappropriate antibiotics in patients with pneumonia admitted to the ICU via the ER.

Association between folate-metabolizing pathway polymorphism and non-Hodgkin lymphoma

Kim, Hee Nam,Lee, Il-Kwon,Kim, Yeo-Kyeoung,Tran, Huong Thi Thanh,Yang, Deok-Hwan,Lee, Je-Jung,Shin, Min–,Ho,Park, Kyeong-Soo,Shin, Myung-Geun,Choi, Jin-Su,Kim, Hyeoung-Joon Blackwell Publishing Ltd 2008 British journal of haematology Vol.140 No.3

<P>Summary</P><P>Polymorphisms in the genes coding folate-metabolizing enzymes affect the risk of some forms of cancer. We investigated the association between these polymorphisms and non-Hodgkin lymphoma (NHL) risk in a population-based study (583 cases and 1700 controls). The <I>MTHFR</I> 677TT and CT genotypes were associated with reduced risk for NHL [odds ratios (OR) = 0·79; 95% confidence intervals (CI) = 0·65–0·98 for 677CT and 0·61; 0·45–0·82 for 677TT] and diffuse large B-cell lymphoma (DLBCL) (OR = 0·68; 0·51–0·88 for 677CT; OR = 0·56; 0·38–0·83 for 677TT). The <I>MTHFR</I> 1298CC genotype was associated with increased risk for NHL (OR = 1·71; 1·07–2·75) and T-cell lymphoma (OR = 3·05; 1·53-6·11). The <I>MTRR</I> 66GG genotype was associated with increased risk for DLBCL (OR = 1·56; 1·03-2·38) and the <I>TYMS</I> 2R2R genotype was associated with increased risk for T-cell lymphoma (OR = 2·83; 1·33–6·01). Using subjects with 3RG3RG as a reference group, <I>TYMS</I> 2R2R was associated with increased risk for T-cell lymphoma (OR = 2·46; 1·04–5·79). Interestingly, we observed a reduced association between the <I>TYMS</I> 2R3RG genotype and DLBCL (OR = 0·61; 0·38–0·99). These results suggest that <I>MTHFR</I>, <I>MTRR</I> and <I>TYMS</I> polymorphisms may play a significant role in the risk for NHL.</P>

Polymorphisms involved in the folate metabolizing pathway and risk of multiple myeloma

Kim, Hee Nam,Kim, Yeo-Kyeoung,Lee, Il-Kwon,Lee, Je-Jung,Yang, Deok-Hwan,Park, Kyeong-Soo,Choi, Jin-Su,Park, Moo Rim,Jo, Deog Yeon,Kim, Hyeoung-Joon Wiley Subscription Services, Inc., A Wiley Company 2007 American journal of hematology Vol.82 No.9

<P>Folate and methionine metabolism plays an essential role in both DNA synthesis and methylation. Polymorphisms in the genes of the folate-dependent enzymes have been shown to affect disease susceptibility. We conducted a Korean population-based case-control study to evaluate whether genetic variation in folate metabolism may have a role in the risk of multiple myeloma (MM). The study subjects were 173 patients with MM and 1,700 population-based controls. The polymorphisms studied include methylenetetrahydrofolate reductase (MTHFR) 677 C > T and 1298 A > C, methionine synthase (MS) 2756 A > G, methionine synthase reductase (MTRR) 66A > G, thymidylate synthase (TS) 28-bp repeat (2R→3R) and 6-bp deletion/insertion. MS 2756 AG genotypes were associated with a 1.5-fold lower risk of MM (OR = 0.66, 95%CI; 0.43–0.99, P = 0.047). There was no association between MTHFR C677T, A1298C, MTRR A66G, TS 2R→3R and 6-bp deletion/insertion polymorphisms and MM. These results suggest that MTHFR C677T, A1298C, MTRR A66G, TS 2R→3R, and 6-bp deletion/insertion do not significantly factor into the pathogenesis of MM in the Korean population, but that MS A2756G polymorphism may play an important role. Am. J. Hematol., 2007. © 2007 Wiley-Liss, Inc.</P>

Surgical outcomes of pure laparoscopic versus open liver resection for intrahepatic cholangiocarcinoma

Kyeong Deok KIM,Jong Man KIM,Manuel LIM,Ji Eun KWON,Eun Sung JEONG,Jaehun YANG,Young Ju OH,Sunghae PARK,Sang Oh YUN,Jinsoo RHU,Gyu-Seong CHOI,Jae-Won JOH 한국간담췌외과학회 2022 Annals of hepato-biliary-pancreatic surgery Vol.26 No.-