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Optimal anesthesia protocols for successful intraoperative neuromonitoring during thyroid surgery
Jiwon Lee(Jiwon Lee),Jung-Man Lee(Jung-Man Lee),Young Jun Chai(Young Jun Chai) 대한신경모니터링학회 2022 Journal of Neuromonitoring & Neurophysiology Vol.2 No.2
There are several factors related to anesthesia that are required for successful intraoperative neuromonitoring (IONM) during thyroid and parathyroid surgery, including proper placement of endotracheal tube, adequate neuromuscular blockade, use of appropriate neuromuscular blockade reversal agent, and pain management. In this review, we summarize the anesthesia issues related to IONM during thyroid and parathyroid surgery.
Jiwon Choi(Jiwon Choi),Keesin Jeong(Keesin Jeong),Haiyoung Jung(Haiyoung Jung) 한국화재소방학회 2022 International Journal of Fire Science and Engineer Vol.36 No.4
Dust and fine dust exist in various forms and can lead to various problems such as dust explosion and air pollution. To reduce them, recently, research on electrospray electric precipitation, among various dust collection methods, has been actively conducted. In this study, comparative analysis experiments were performed on microdroplet generation characteristics for direct and indirect charging methods of electrospray electric precipitation. A visualization device was fabricated to generate microdroplets, and microdroplets were photographed with a high-magnification camera according to each charging method. The size and number of microdroplets were then analyzed via ImageJ software.
Jung, Jiwon,Hah, Hoe Jin,Lee, Tae jin,Lee, Jae Gil,Lee, Jeong Beom,Kim, Jongjung,Soon, Jiyong,Ryu, Ji Heon,Kim, Jae Jeong,Oh, Seung M. The Korean Electrochemical Society 2017 Journal of electrochemical science and technology Vol.8 No.1
A comparative study was performed on the passivating abilities of surface films generated on lithium titanate (LTO; $Li_4Ti_5O_{12}$) electrodes during pre-cycling at two different rates. The surface film deposited at a faster pre-cycling rate (i.e., 0.5 C) is irregularly shaped and unevenly covers the LTO electrode. Owing to the incomplete coverage of the protective film, this LTO electrode exhibits poor passivating ability. Additional electrolyte decomposition and concomitant film deposition occur during subsequent charge/discharge cycles. As a result of the thick surface film, severe cell polarization occurs and eventually causes cell failure. However, pre-cycling the Li/LTO cell at a slower rate (0.1 C) improves cell polarization and capacity retention; this occurs because the surface film uniformly covers the LTO electrode and provides strong passivation. Accordingly, there is no significant film deposition during subsequent charge/discharge cycling. Additionally, self-discharge is reduced during high-temperature storage.
Unsupervised Liver Segmentation using Domain Adaptation in MRI
Jiwon Jung(정지원),Ehwa Yang(양이화),Woo Kyoung Jeong(정우경),Kyoung Doo Song(송경두),Jae-Hun Kim(김재훈) 한국통신학회 2022 한국통신학회 학술대회논문집 Vol.2022 No.2
Liver segmentation is an essential procedure in Computer-Aided Diagnosis (CAD), surgery, and volume measurement for radiotherapy. But it is still a challenging task to extract liver tissue parenchyma due to nearby organs with similar intensities. When we segment the liver using supervised deep learning, fully-annotated datasets are needed. However, it is hard to obtain well-annotated labels because of their diverse appearances such as size and shape. Also, it takes expensive costs for labeling. In this paper, we performed unsupervised liver segmentation in unlabeled Magnetic Resonance Imaging (MRI) datasets using deep learning. To generate labels of MRI, the domain adaptation technique is applied with CT images containing well-annotated labels. We trained the segmentation model with the MRI dataset which is transferred from CT images and evaluated the model on real MRI datasets. The performance of our model shows 88% dice similarity coefficient accuracy. This study could be one of the solutions to handle the difficulty to train deep learning models with unlabeled datasets.
Jiwon Jung,Young-Ju Lim,Eun Ok Kim,Sung-Han Kim 대한의학회 2022 Journal of Korean medical science Vol.37 No.2
Background: Preventive measures are needed to reduce the risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection among healthcare workers (HCWs). Notably, hospital staff are usually exposed when they are unmasked. There are limited data on the risk of transmission during mealtimes at hospital staff cafeterias. We aimed to evaluate the risk of transmission in cafeterias. Methods: From January 2020 through September 2021, we analyzed the risk of SARS-CoV-2 transmission through closed-circuit television and radio-frequency identification tracking and follow-up testing when 33 HCWs, who were eventually diagnosed as coronavirus disease 2019 (COVID-19), ate in staff cafeterias during the infectious period. The seats were arranged so the HCWs would sit on either side without facing each other. There were no plastic barriers installed, and HCWs were encouraged not to talk during meals. Results: Three of the 119 individuals who ate at seats next (about 30 cm) to index during the period of transmission and underwent follow-up SARS-CoV-2 polymerase chain reaction tests were diagnosed with COVID-19 (2.5%; 95% confidence interval, 0.5–7.4%). Among the 98 HCWs who were investigated about talking during meals, there was a higher attack rate among those who spoke with each other than among those who did not (12.5% [3/24] vs. 0% [0/74], P = 0.013). Conclusion: The risk of transmission in a hospital’s employee cafeterias is not high with sideby-side seating, especially in the absence of conversation.
Incidence and Risk Factors of Ocular Infection Caused by <i>Staphylococcus aureus</i> Bacteremia
Jung, Jiwon,Lee, Junyeop,Yu, Shi Nae,Kim, Yong Kyun,Lee, Ju Young,Sung, Heungsup,Kim, Mi-Na,Kim, Sung-Han,Lee, Sang-Oh,Choi, Sang-Ho,Woo, Jun Hee,Lee, Joo Yong,Kim, Yang Soo,Chong, Yong Pil American Society for Microbiology 2016 Antimicrobial Agents and Chemotherapy Vol.60 No.4
<P>Staphylococcus aureus bacteremia (SAB) often leads to ocular infections, including endophthalmitis and chorioretinitis. However, the incidence, risk factors, and outcomes of ocular infections complicated by SAB are largely unknown. We retrospectively analyzed the incidence and risk factors of ocular involvement in a prospective cohort of patients with SAB at a tertiary-care hospital. Ophthalmologists reviewed the fundoscopic findings and classified the ocular infections as endophthalmitis or chorioretinitis. During the 5-year study period, 1,109 patients had SAB, and data for 612 (55%) who underwent ophthalmic examinations within 14 days after SAB onset were analyzed. Of those 612 patients, 56 (9% [95% confidence interval [CI], 7 to 12%]) had ocular involvement, including 15 (2.5%) with endophthalmitis and 41 (6.7%) with chorioretinitis. In a multivariate analysis, infective endocarditis (adjusted odds ratio [aOR], 5.74 [95% CI, 2.25 to 14.64]) and metastatic infection (aOR, 2.38 [95% CI, 1.29 to 4.39]) were independent risk factors for ocular involvement. Of the 47 patients with ocular involvement who could communicate, only 17 (36%) had visual disturbances. Two-thirds of the patients with endophthalmitis (10/15 patients) were treated with intravitreal antibiotics combined with parenteral antibiotics, whereas all of the patients with chorioretinitis were treated only with systemic antibiotics. No patients became blind. Among 42 patients for whom follow-up assessments were available, the ocular lesions improved in 29 (69%) but remained the same in the others. Ocular involvement was independently associated with death within 30 days after SAB onset. Ocular involvement is not uncommon among patients with SAB. Routine ophthalmic examinations should be considered for patients with infective endocarditis or metastatic infections caused by SAB.</P>
Jung, Jiwon,Ryu, Seonhyung,Ki, In A,Woo, Hyun Ae,Lee, Kyunglim MDPI 2018 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Vol.19 No.6
<P>Na,K-ATPase is an ionic pump that regulates the osmotic equilibrium and membrane potential of cells and also functions as a signal transducer. The interaction of Na,K-ATPase with translationally controlled tumor protein (TCTP) results, among others, in the inhibition of the former’s pump activity and in the initiation of manifold biological and pathological phenomena. These phenomena include hypertension and cataract development in TCTP-overexpressing transgenic mice, as well as the induction of tumorigenesis signaling pathways and the activation of Src that ultimately leads to cell proliferation and migration. This review attempts to collate the biological effects of Na,K-ATPase and TCTP interaction and suggests that this interaction has the potential to serve as a possible therapeutic target for selected diseases.</P>
Nosocomial Outbreak of COVID-19 in a Hematologic Ward
Jung Jiwon,Jungmin Lee,Seongmin Jo,Bae Seongman,Ji Yeun Kim,Cha Hye Hee,Lim Young-Ju,Kwak Sun Hee,Hong Min Jee,Kim Eun Ok,Bae Joon-Yong,Kang Changmin,Sung Minki,Park Man-Seong,Kim Sung-Han 대한감염학회 2021 Infection and Chemotherapy Vol.53 No.2
Background: Coronavirus disease 2019 (COVID-19) outbreaks occur in hospitals in many parts of the world. In hospital settings, the possibility of airborne transmission needs to be investigated thoroughly. Materials and Methods: There was a nosocomial outbreak of COVID-19 in a hematologic ward in a tertiary hospital, Seoul, Korea. We found 11 patients and guardians with COVID-19 through vigorous contact tracing and closed-circuit television monitoring. We found one patient who probably had acquired COVID-19 through airborne-transmission. We performed airflow investigation with simulation software, whole-genome sequencing of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Results: Of the nine individuals with COVID-19 who had been in the hematologic ward, six stayed in one multi-patient room (Room 36), and other three stayed in different rooms (Room 1, 34, 35). Guardian in room 35 was close contact to cases in room 36, and patient in room 34 used the shared bathroom for teeth brushing 40 minutes after index used. Airflow simulation revealed that air was spread from the bathroom to the adjacent room 1 while patient in room 1 did not used the shared bathroom. Airflow was associated with poor ventilation in shared bathroom due to dysfunctioning air-exhaust, grill on the door of shared bathroom and the unintended negative pressure of adjacent room. Conclusion: Transmission of SARS-CoV-2 in the hematologic ward occurred rapidly in the multi-patient room and shared bathroom settings. In addition, there was a case of possible airborne transmission due to unexpected airflow.
Frequent Occurrence of SARS-CoV-2 Transmission among Non-close Contacts Exposed to COVID-19 Patients
Jung Jiwon,Lee Jungmin,Kim Eunju,Namgung Songhee,Kim Younjin,Yun Mina,Lim Young-Ju,Kim Eun Ok,Bae Seongman,Kim Mi-Na,Lee Sun-Mi,Park Man-Seong,Kim Sung-Han 대한의학회 2021 Journal of Korean medical science Vol.36 No.33
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission among non-close contacts is not infrequent. We evaluated the proportion and circumstances of individuals to whom SARS-CoV-2 was transmitted without close contact with the index patient in a nosocomial outbreak in a tertiary care hospital in Korea. From March 2020 to March 2021, there were 36 secondary cases from 14 SARS-CoV-2 infected individuals. Of the 36 secondary cases, 26 (72%) had been classified as close contact and the remaining 10 (28%) were classified as non-close contact. Of the 10 non-close contact, 4 had short conversations with both individuals masked, 4 shared a space without any conversation with both masked, and the remaining 2 entered the space after the index had left. At least one quarter of SARSCoV-2 transmissions occurred among non-close contacts. The definition of close contact for SARS-CoV-2 exposure based on the mode of droplet transmission should be revised to reflect the airborne nature of SARS-CoV-2 transmission.