TOC를 이용한 업무프로세스 효율성 향상

배혜림,이승현,조남욱 한국정보시스템학회 2006 情報시스템硏究 Vol.15 No.1

제조 기업 중심의 유비쿼터스 기술 활용 방안

공재현,배혜림 동의대학교 경제경영전략연구소 2009 經濟經營硏究 Vol.4 No.2

The objective of this paper is to suggest ubiquitous technology applications in manufacturing enterprises. We suggest applicable methods for real-time data of logistic management, manufacturing management, human resource management and history management. And we propose the structure of information systems for real-time data collection, integrate ubiquitous data through supply chain around manufacturing enterprises. Finally we invent prototype ubiquitous system for supply chain management, manufacturing management, worker management and post sales services to show possibility of ubiquitous applications

NIHSS 활용을 통한 뇌졸중 환자 간호의 질향상 전략

박경현,송경애,공혜성,나화주,유수경,박소영,김상희,최혜림,배희준,한문구,양미화 한국의료QA학회 2009 한국의료질향상학회지 Vol.15 No.2

문제: 뇌졸중 환자를 돌보는 간호현장에서는 급성기 뇌졸중 환자의 증상악화에 대한 조기사정과 적절한 대처가 매우 중요한 문제이다. 그러나 임상현장에서는 이를 객관화하고 수치화하여 모든 의료진이 의사소통할 수 있는 유용한 도구를 사용하고 있지는 못하는 실정이다. 이러한 문제를 해결하기위해 NIHSS(National Institute of Health Stroke Scale)를 신경과 진료의사를 중심으로활용하고 있지만 아직 간호현장에서는보편적으로사용하지 않고있다. 이에 뇌졸중환자간호에 NIHSS를 활용하여 뇌졸중 증상악화의 조기사정과 빠른 대처로 궁극적으로는 뇌졸중환자 간호의 질을보다 향상시키기 위하여 본활동이 시도되었다. 목적: 첫째, 간호사의 NIHSS 측정 신뢰도의 현수준을 점검하고 이를향상시키기 위한 프로그램을 개발·적용한다. 둘째, 간호사가급성기 뇌졸중환자에게 NIHSS 측정을 통하여 뇌졸중악화를 얼마나 예측할 수 있는지 분석하고 이를 향상시킬수있는 방법을 모색한다. 셋째, 궁극적으로 급성기 뇌졸중 환자의 증상악화의 조기 발견과치료를위한의료진의 올바른 대처지침을 마련하여 이를 적용한다. 의료기관: 경기도에 소재한 대학병원의 뇌졸중 집중치료실 질 향상 활동: 첫째, 간호사의 NIHSS 측정 신뢰도 향상을 위해 「NIHSS 간호사 교육 프로그램」을 마련하였다.

Treatment with bisphenol A and methoxychlor results in the growth of human breast cancer cells and alteration of the expression of cell cycle-related genes, cyclin D1 and p21, via an estrogen receptor-dependent signaling pathway.

Lee, Hye-Rim,Hwang, Kyung-A,Park, Min-Ah,Yi, Bo-Rim,Jeung, Eui-Bae,Choi, Kyung-Chul UNKNOWN 2012 INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE Vol.29 No.5

<P>Various endocrine disrupting chemicals (EDCs) are exogenous compounds found in the environment and have the potential to interfere with the endocrine system and hormonal regulation. Among EDCs, bisphenol?A (BPA) and 1,1,1-trichloro-2,2-bis(4-methoxyphenol)-ethane [methoxychlor (MXC)] have estrogenic activity resulting in a variety of dysfunctions in the E2-mediated response by binding to estrogen receptors (ERs), causing human health problems such as abnormal reproduction and carcinogenesis. In this study, we investigated the effects of BPA and MXC on cell proliferation facilitated by ER signaling in human breast cancer cells. MCF-7 cells are known to be ERα-positive and to be a highly E2-responsive cancer cell line; these cells are, therefore, a useful in?vitro model for detecting estrogenic activity in response to EDCs. We evaluated cancer cell proliferation following BPA and MXC treatment using an MTT assay. We analyzed alterations in the expression of genes associated with the cell cycle in MCF-7 cells by semi-quantitative reverse-transcription PCR following treatment with BPA or MXC compared to EtOH. To determine whether BPA and MXC stimulate cancer cell growth though ER signaling, we co-treated the cells with agonists (propyl pyrazoletriol, PPT; and diarylpropionitrile, DPN) or an antagonist (ICI 182,780) of ER signaling and reduced ERα gene expression via siRNA in MCF-7 cells before treatment with EDCs. These studies confirmed the carcinogenicity of EDCs in?vitro. As a result, BPA and MXC induced the cancer cell proliferation by the upregulation of genes that promote the cell cycle and the downregulation of anti-proliferative genes, especially ones affecting the G1/S transition via ERα signaling. These collective results confirm the carcinogenicity of these EDCs in?vitro. Further studies are required to determine whether EDCs promote carcinogenesis in?vivo.</P>

Quench properties of superconducting fault current limiters connected in parallel

Kim, Hye-Rim,Park, Hyo-Sang,Park, Kwon-Bae,Hyun, Ok-Bae,Hwang, Si-Dole The Korean Superconductivity Society 2002 Progress in superconductivity Vol.3 No.2

We investigated the quench properties of superconducting fault current limiters (SFCLs) connected in parallel. It was carried out as an effort to scale up the current capacity of SFCL toys texts. SFCLs were based on $YBa_2$$Cu_3$$O_{7}$ films coated in-situ with a gold layer and fabricated by patterning the films into 2 mm wide and 42 cm long meander lines by photolithography. Two SFCLS were connected in parallel and tested with simulated AC fault currents. Initially the current was divided unequally into branches of parallel connection due to unequal resistance of the branches. However, once quench started in the SFCLs, the current oscillated between the branches and then was distributed nearly equally between the branches. In other words, the elements quenched simultaneously. The oscillation amplitude decreased as the source voltage was increased: the oscillation was the most prominent near the quench current. The observed oscillation and the consequent simultaneous quench was understood in terms of quench start and development in the SFCLs.

A Hierarchical Cluster Analysis of Normal-Tension Glaucoma Using Spectral-Domain Optical Coherence Tomography Parameters

Bae, Hyoung Won,Ji, Yongwoo,Lee, Hye Sun,Lee, Naeun,Hong, Samin,Seong, Gong Je,Sung, Kyung Rim,Kim, Chan Yun Raven Press 2015 Journal of glaucoma Vol.24 No.4

PURPOSE:: Normal-tension glaucoma (NTG) is a heterogenous disease, and there is still controversy about subclassifications of this disorder. On the basis of spectral-domain optical coherence tomography (SD-OCT), we subdivided NTG with hierarchical cluster analysis using optic nerve head (ONH) parameters and retinal nerve fiber layer (RNFL) thicknesses. PATIENTS AND METHODS:: A total of 200 eyes of 200 NTG patients between March 2011 and June 2012 underwent SD-OCT scans to measure ONH parameters and RNFL thicknesses. We classified NTG into homogenous subgroups based on these variables using a hierarchical cluster analysis, and compared clusters to evaluate diverse NTG characteristics. RESULTS:: Three clusters were found after hierarchical cluster analysis. Cluster 1 (62 eyes) had the thickest RNFL and widest rim area, and showed early glaucoma features. Cluster 2 (60 eyes) was characterized by the largest cup/disc ratio and cup volume, and showed advanced glaucomatous damage. Cluster 3 (78 eyes) had small disc areas in SD-OCT and were comprised of patients with significantly younger age, longer axial length, and greater myopia than the other 2 groups. CONCLUSIONS:: A hierarchical cluster analysis of SD-OCT scans divided NTG patients into 3 groups based upon ONH parameters and RNFL thicknesses. It is anticipated that the small disc area group comprised of younger and more myopic patients may show unique features unlike the other 2 groups.

Recovery Characteristics of Coated Conductors

Hye-Rim Kim,Chung Ryul Park,Seong-Woo Yim,Seung-Duck Yu,Ok-Bae Hyun IEEE 2010 IEEE transactions on applied superconductivity Vol.20 No.3

<P>We investigated recovery characteristics of commercially-available coated conductors (CCs) after quenches. The CC had a hastelloy substrate and an Ag protection layer without stabilizer. The CC samples were subjected to simulated AC over-current to induce quenches. Both resistance measurement and bubble imaging were taken during the recovery. The samples were immersed in liquid nitrogen during the experiment. During the recovery, resistance of CC samples decreased monotonously to zero in some cases. In other cases, it decreased in two steps, first slowly and then faster. Resistance behavior depended on voltages applied during over-current period as well as sample dimension. It was related to cooling by liquid nitrogen and recovery propagation behavior, which could be observed directly by bubble imaging. The bubble imaging and the resistance measurement results matched with each other. The recovery generally propagated faster in thinner and wider samples as well as when higher voltages were applied during the over-current period. This recovery behavior was understood quantitatively with the concept of heat transfer to the surrounding liquid nitrogen. Heat balance equation was solved, and the calculated data were compared with experimental results.</P>

[시설운영 및 기타] Glaucoma-therapeutic effects of exosome-rich conditioned media from human amniotic membrane stem cells

Hye-Rim Seong,Sangryong Park,Chan Ho Noh,Cuicui Wang,Sumin Cho,Seok Jin Hong,Tae Myoung Kim,Ehn-Kyoung Choi,Yun-Bae Kim 한국실험동물학회 2022 한국실험동물학회 학술발표대회 논문집 Vol.2022 No.1

Quench Development in Superconducting Fault Current Limiters Based on YBCO Films

Hye-Rim Kim,Seong-Woo Yim,Sung-Yong Oh,Seung-Deok Yoo,Ok-Bae Hyun IEEE 2009 IEEE transactions on applied superconductivity Vol.19 No.3

<P>We measured and analyzed quench development in superconducting fault current limiters (SFCLs) based on Au/YBa<SUB>2</SUB>Cu<SUB>3</SUB>O<SUB>7</SUB> thin films, taking temperature dependence of thermal parameters into consideration. The SFCLs were fabricated by patterning Au/YBCO films grown on 100 mm-diameter sapphire substrates. They were subjected to simulated AC fault currents for quench development measurement. The samples were immersed in liquid nitrogen during the experiment. The quench resistance increased rapidly first and then moderately fast. The increase slowed down afterwards. Data were analyzed quantitatively with the concept of heat transfer within the SFCLs. A heat balance equation was derived and solved, taking into consideration temperature dependence of thermal parameters of sapphire substrates. The solutions agreed with data well. They explained the quench behavior both prior to and after completion of quench propagation. Dependence of quench development on applied voltages could be also understood quantitatively.</P>

Demonstration of a Superconducting Fault Current Limiter in a Real Grid

Hye-Rim Kim,Seung-Duck Yu,Heesun Kim,Woo-Seok Kim,Seong-Eun Yang,Ji-Young Lee,Ok-Bae Hyun IEEE 2013 IEEE transactions on applied superconductivity Vol.23 No.3

<P>A 22.9 kV superconducting fault current limiter (SFCL) has been in operation in a real grid in Korea. The SFCL is of hybrid type, in which the fault current is detected by a superconductor and bypassed by a high-speed switch to a reactor in a parallel circuit for current limitation. It has a current rating of 630 A, and has been operated in a distribution line in Icheon Substation, which is located in a suburban area with moderate loads. The SFCL has been operated very stably with no degradation in performance. Temperatures and level of the liquid nitrogen cooling the superconductors have been maintained within 0.1 K and 0.3 cm, respectively, under large daily load variation of about 100 A. Performance of the SFCL was tested by measuring minimum limitation current and impedance of the SFCL, and was proved to maintain the initial level of performance. There was a single line-to-ground fault event in the distribution line where the SFCL has been operated, and the SFCL limited the fault current successfully. Data analysis showed that the SFCL limited the current as designed. These results proved reliability and performance of the SFCL.</P>