抗癌丹을 投與한 胃癌 患者 105例에 對한 臨床報告

유화승,최우진,이용연,서상훈,조정효,이연월,손창규,조종관 대전대학교 한방병원 2000 惠和醫學 Vol.9 No.2

Clinical studies were carried out 105 cases of patients with stomach cancer treated by Hangamdan(抗癌丹) from January 1th 1998 to September 30th 2000. The results were summarized as follows; 1. Distribution of those attached by stomach cancer, by sex, showed that Male is more then Female, by age, showed that the number of forties, fifties, sixties are majority. 2. Distribution of diagnostic stage, in descending order; stage Ⅲ(45.1%, top), stage Ⅳ(40.2%). 3. The effects of maintenance and improvement in the symptoms with traditional oriental therapy(77.8%) and combined treatment of western and oriental therapy(92.3%) were observed. The effects of the symptoms were as follows; abdominal pain (16.3%), general body weakness(10.5%), nausea&vomiting (8.6%), diarrhea(6.7%) and etc, in orders. 4. Analysis of hematology attached by stomach cancer, maintenance and increasing of WBC(89.4%), RBC(63.6%), Hgb(62.3%), Platelet(95.6%) were observed. After taken Hangamdan, the safety of the liver and kidney were as follows; maintenance and decreasing of AST(85.3%), ALT(91.6%), BUN(84.8%), Creatinine(92.4%) were observed. 5. Analysis of IL-12 and IFN-γ attached by stomach cancer, increasing of IL-12(39.1%), IFN-γ(69.6%) were observed. 6. Analysis of QOL attached by stomach cancer, maintenance and improvement of combined treatment of western and oriental therapy(91%), traditional oriental therapy(85.2%) were observed. 7. Analysis of survival in patients with Ⅳ stage of stomach cancer, above 6 months(17.1%), 12 months(85.2%) were observed. 8. Analysis of antitumor effects, maintenance of traditional oriental therapy(81.5%) and maintenance and improvement of combined treatment of western and oriental therapy(89.7%) were observed. Analysis of tumor marker attached by stomach cancer, maintenance of CEA(85.7%) were observed. 9. Analysis of curative valuation, maintenance and improvement of traditional oriental therapy(77.7%), combined treatment of western and oriental therapy(82.1%) were observed. From the above results, it is suggested that Hangamdan has significant effects of antitumor and immune activity, also could be usefully applied for stomach cancer patients by combination with western therapy or alone.

西歐 代替醫學의 癌 治療에 關한 硏究

兪和承,李容淵,徐祥熏,崔宇鎭,曺政孝,李淵月,孫彰奎,趙鍾寬 대한한방종양학회 2000 대한한방종양학회지 Vol.6 No.1

At here, we investigated the historical background, current stage, and concrete therapies of altematives in cancer therapy. We obatined the conclusion below. 1. Alternative medicine(AM) is a unothodoxial medical physiology, medical practice or intervension that overcome the side effects. faults, limits of coventional medicine. 2. Recentely, as emerging New-age movement, collgpse of Decarte's mecanical cosmology, and emphasis on patient rights, the interest of AM is increased, and foreign & domestic use rates of AM are risen. 3. After coventional medicine in cancer therapies tha depends on poerations, radiations, and chemotherapy is bounded, Altematives in cancer therapy are rapidly developed, and the majority of users are often considered satisfactory. 4. Alternatives in cancer therapy are classified six boundaries; Diet and Nutrition, MInd-body Technique, Integrated System, Pharmacologic and Biologictreatments, Immuno Enhanced Therapy, Immuno Enthaced Therapy, Natural and herbal medicine. 5. Looking at contents of Alternatives in cancer therapy, we get to know most of them are similar to the treatment of oriental medicine in holistic method, therapy, philosophy. If we synthesize the alternative medicine's treatment mentioned above and investigate it with oriental medical viewpoint, that may help us approach the conquest of cancer and improve the rate of cure. that may help us approach the conquest of cancer and improve the rate of cure. 6. It is certain that foreign AM will be imported reversely, and we must prepare for rebuilding of Korean traditional AM systemically, investing for activity positively, making national policy for medical system.

抗癌免疫 1號方을 投與한 胃癌患者 40例에 對한 臨床考察

兪和承,曺政孝,정경규,李淵月,趙珍浩,趙鍾寬 대한한방종양학회 1998 대한한방종양학회지 Vol.4 No.1

Clinical studies were carried out 40 cases of patients with stomach cancer treated by "Hangammyunyouk Ⅰ(抗癌免疫1號方)". from September 1th 1997 to May 1th 1998. The results were summarized as follows; 1. Distribution of those attached by stomach cancer, by sex, showed that Male is more then Female. by age, showed that the number of fifies is majority. 2. Dstribution of diagnostic stage. on descending order, stage Ⅲ, stage Ⅳ. 3. Distribution of treatment attached by stomach cancer, in descending order: Chemotherapy and operation. chemotherapy. Radiation therapy and operation. 4. After taken herb medicine, the effects according to the symptoms wer as follows; Nausea and Vomiting. Constipation, General body weakness, Aberage efficacy of symptoms were 68.1%. 5. Analysis of hematology attached by stomach cancer, increasing of WBC(61.5%), Hgb(54.5%), platelt(62.5%) were observed.

외국산 양주의 진위판정에 관한 연구

박유신,백승화,조후종 명지대학교 자연과학연구소 1994 자연과학논문집 Vol.11 No.-

외국산 양주의 진위를 판정하는 방법을 수립하기 위하여 GC를 이용해서 71종의 표준양주에 함유되어 있는 ethyl acetate와 3종류의 고급 알코올, 즉n-propanol, iso-butanol,iso amyl alchol의 함량을 측정하고, 각양주의 UV최애흡수파장과 흡광도를 측정하여 외국산 양주의 진위판정 기준으로 이용하였다.이와 같은 기준에 의하여 가짜로 의심되는 3종류의 양주를 분석한 결과 다음과 같은 판정ㅇ 가능하였다. 1종은 저급의 외국산 양주가 고급 외국산 양주고 위조된 것이고, 2종은 국산양주가 외국산 양주로 위조된 것으로 판명되었다. This study attempts to establish the methods to evaluate adulterated foreign liquors, we anlized the content of ethyl acetate, n-propanol, iso-butanol and iso-amyl alcohol in 578 reliable and 3 unreliable foriegn liquors and 14 Korean liquors by gas chromatography. Subsequently, UV absorption maximum wavelengh and optical desity of these liquors were measured. These contents of the 3 unreliable foreign liquors were compared with the contents of the reliable liquors. The results were as follows: 1.The Jack Daniels(Old No.7)of foreign bourbon whisky was adultesated to Cammus(VSOP)of foreign cognac brandy. 2.The Captain Q spirit made in Korea was adultesated to Chivas Regal(12 years) of foreign scotch whisky. 3.The Old of spirit made in Korea was adultesated to Johnnie Walker(Black Label, 12 years) of foreign scotch whisky. Therefore reliability if foreign liquor could be decided by teh content of ethyl acetate and higher alchols the measurment fo UV absorption maximum wavelengh and optical density in liquors.

연구논문 : 항공기 배출량 산정 방법에 따른 공항주변 대기오염 영향분석연구

한승재 ( Seung Jae Han ),유정우 ( Jung Woo Yoo1 ),임윤진 ( Yoon Jin Lim ),이순환 ( Soon Hwan Lee3 ),이화운 ( Hwa Woon Lee ) 한국환경과학회 2014 한국환경과학회지 Vol.23 No.12

Emissions from aircraft have impacts on the air pollution of airport and the surrounding area. There are methods of emissions calculated as Tier 1, Tier2, Tier 3A and Tier 3B. Thus, this study investigated emissions from aircraft at the Gimhae International Airport using EDMS(Emissions & Dispersion Modeling System) program. Results of estimation from aviation emissions, Tier 3B considering all parts which can occur at the airport has the largest amount emissions. In order to understand the relation between aviation emissions and distribution of ozone concentration over airport area, numerical evaluation were carried out. Although the difference of surface ozone distribution between numerical assessment with and without aviation emissions was little, effects of air pollution at airport area from aviation emissions of NOx and VOCs.

코클리어 메카닉스의 신경동조모델

백승화,유선국,윤태성 明知大學校 産業技術硏究所 1987 産業技術硏究所論文集 Vol.6 No.2

A neural tuning model is analyzed which is based on the phenomena for basilar membrane motion, and the responses of tuning curves. By assuming the cochlear fluied is incompressible and non-viscous, a pair of second order differential equations for basilar membrane motion is solved and the neural tuning response for hair cell excitation is analyzed by linearly combining the pressure across the basilar membrane with its displacement. The sharply tuning filter mechanism with different characteristic place being sensitive to different characteristic frequency is obtained. The differences between the mechanical properties for basilar membrane and the neural tuning reponses are explained.

抗癌丹을 投與한 各種 癌患者 320例에 對한 考察

曺政孝,兪和承,李淵月,孫彰奎,趙鍾寬 대전대학교 한의학연구소 2004 혜화의학회지 Vol.12 No.2

The purpose of this study was to investigate the effects of Hangamdan(抗癌丹). The clinical study was carried out 320 cases of patients with cancer treated by Hangamdan(抗癌丹) from May 1st 1998 to September 1st 1999. The results were summarized as follows; 1. The effects of improvement in the symptoms with traditional oriental cancer therapy(47.6%) were higher than combined treatment of western and oriental therapy(37.4%). 2. In the analysis of hematology, maintenance and increasing of WBC(86.2%), Hgb(87.2%), Platelet(97.6%) RBC(81.1%) were Observed. In the analyses of tumor marker, maintenance and decreasing of CEA(76%), CA19-9(88.8%), AFP(69.2%) were observed. 3. In the analysis of safety, maintenance and decreasing of AST(93.1%), AL.T(95%), BUN(92.2%), Creatinine(93.6%) were observed. 4. In the analysis of QOL attached by cancer, combined treatment of western and oriental therapy(maintenance and improvement; 91.8%) was higher than traditional oriental cancer therapy(maintenance and improvement; 79.3%) 5. In the analysis of survival in patients with terminal cancer, above 6 months(46.3%), 12 months( 19.2%). 6. In the analysis of antitumor effects, combined treatment of western and oriental therapy(maintenance 71.6% improvement 12.8%) was higher than traditional oriental therapy (maintenance 66.7% improvement 9.5%). 7. In the analysis of curative evaluation, combined treatment of western and oriental therapy(maintenance 40.4% improvement 41.8%) was higher than traditional oriental therapy (maintenance 23.8% improvement 46.1%). 8. In the analysis of IL-12 and IFN-γ attached by cancer, increasing of IL-12(32.3%), IFN-γ(41.5%) were observed. From the above results, it is suggested that Hangamdan has significant effects of antitumor and immune activity, also could be usefully applied for cancer patients by combination with western therapy or alone.

急性 骨髓性 白血病 患者 1例에 對한 臨床報告

조정효,유화승,최우진,이용연,서상훈,이연월,손창규,조종관 대전대학교 한방병원 2000 惠和醫學 Vol.9 No.2

AML is the most common type of leukemia in adults. AML(acute myeloid leukaemia) is characterised by a rapid accumulation of abnormal white blood cells in the blood and bone marrow, resulting in severe anemia, and possibly infection, and hemorrhage during the course of the disease. In general the prognosis of patient with relapsed AML is poor. At this time, however, the only potentially curative therapy for relapsed patients is allogeneic BMT(bone marrow transplantation). This clinical study were carried out 1 case of female patient aged 44 with relapsed AML treated by herb medicine. At the time of admission, she complained of mild fever, nausea, vomitting, abdominal pain, anorexia and no sign of bleeding. For the 10 days of admission, she was treated with Oriental-Western medicine and all the symptoms were disappeared. After that, the syptoms were aggravated because of secondary infection. Anyway, above result showed the possibility of Oriental therapy as Supportive Care in AML.

집쥐에 의한 슴새 번식성공률 감소

남기백,유승화,김동원,유정칠 경희대학교 한국조류연구소 2002 연구보고 Vol.8 No.1

본 조사는 2001년 6월 25일부터 30일, 8월 12일부터 17일, 10월 20~25일까지 제주도 북제주군 추자면에 위치한 사수도에서 집단 번식하는 슴새의 번식성공률을 조사하였다. 현재 사수도에는 약 4000쌍 정도의 슴새가 번식을 하는 것으로 조사되었다. 총 110개의 둥지를 관찰한 결과, 부화률은 약 15%로 나타났으며, 전체 번식성공률은 약 3%로 나타났다. 전체 번식실패률은 96.4%로 나타났으며, 번식실패 요인으로 집쥐에 의한 포식이 92.5%로 가장 높게 나타났다. 또한 포란기와 부화기에 포식률이 각각 42%, 36%로 육추기의 포식률(11%)보다 높게 나타났다. The rate of breeding success of Streaked Shearwaters (Calonectris leucomelas) was studied at Sasu-islet, in chuja-do, cheju island during 25-30 June, 12-17 August, 20-25 October 2001. The breeding population of Streaked Shearwaters at Sasu-islet is estimated to be about 4,000 pairs. This study was based on detailed observations of 110 nests dispersed over a wide range of nest habitats within colony. Hatching success was 15% (n=17), breeding success was 3% (n=3) and breeding failure was 96% (n=106). Norway Rat(Rattus norvegicus) were responsible for failure of at least 89% of all the breeding failure. The predation rates of both incubation and hatiching periods was higher than that of rearing period.

冬蟲夏草의 抗轉移와 免疫增進에 關한 硏究

최우진,유화승,이용연,서상훈,조정효,이연월,손창규,조종관 대전대학교 한방병원 2000 惠和醫學 Vol.9 No.2

This experimental study was carried out to evaluate the effects of Cordiceps sinensis on the antimetastasis and immune activity. In order to investigate the effect of Cordiceps sinensis, the followings were performed; Cytotoxicity, inhibition of MMP-2 & MMP-9 gene expression, fraction of CD4+, CD8+, CD19+ in splenic cell, the moprphological change of splenic cells, gene expression of IL-12(p35), IL-12(p40), IFN-?? and splenic cell proliferation by CS-E. The results were obtained as follows. 1. CS-E did not present cytotoxic effect on L+14, B16-F10 melanoma cells and HMCB. 2. CS-E inhibited MMP-2 and MMP-9 gene expression more effectively compared with control group. 3. CS-E inhibited invasion of B16-F10 melanoma cells more effectively compared with control group. 4. CS-E helped CD4+, CD8+, CD19+ expression more effectively compared with control group. 5. CS-E activated phagocytic cells in spleen more effectively compared with control group. 6. CS-E helped IL-12(p35), IL-12(p40), IFN-?? gene expression in splenic cell more effectively compared with control group. 7. CS-E activated splenic cell proliferation more effectively compared with control group. From above findings, it is suggested that CS-E is able to inhibit metastasis of cancer and activate immune response system.