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- 저자 : ( Hui-ling Chiou ) (검색결과 2 건)
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A Research on the Impact of Taiwan’s Cultural Colors on Cultural Identity
I-Ling Shih,Yu-Chiou Tchen,Chia-Hui Huang 한국일러스트레이션학회 2019 일러스트레이션 포럼 Vol.20 No.61
Taiwan is a country composed of diverse ethnic groups, and the people in Taiwan have not completely identified with a particular culture in the midst of changing history. According to a recent research, Taiwan has entered the phase of “national identity.” It is the hope of this research that the Taiwanese people will be able to identify themselves with the uniqueness of the Taiwanese culture, and will have greater self-confidence in the process of cultural identity. This research studied the colors expressed in the Taiwanese culture because these colors are infused in everyday living and accumulated in culture. We see these colors every day and get accustomed to them, and often do not know they contain special meanings. So we do not understand the cultural meanings embedded in these colors. Countries closest to Taiwan like Korea, Japan, Thailand, India have organizations that are almost, if not already, at the national level committed to researching and preserving cultural colors. Only Taiwan lacks such an organization. So most people do not understand cultural colors, and miss an observational perspective on Taiwan’s cultural identify. This research explored the influence of Taiwan’s cultural colors on cultural identity, and included a curriculum design and implementation with a theme on “Cultural Colors in Life” in a university’s general education course for the first and second-year students. This curriculum used Walker’s “Big Idea” to design and plan three themed courses on etiquette and customs, nature and ecosystems, land and beliefs in Taiwan; and henceforth introducing the three cultural colors of “Taiwan Form(Red),” “Taiwan Chic(Green)” and “Taiwan Gene (Gold)” into the course content. Each theme included teaching activities like the explanation of the cultural color, the viewing and analysis of a short film “Colorful Taiwan” by Public Television Service(PTS), and so on. A total of four consecutive weeks of teaching activities related to the theme were planned and implemented. The analysis of student questionnaire results shows that after taking the “Cultural Colors in Life” course, students understand more clearly about the cultural colors represented by “Taiwan Red,” “Taiwan Green” and “Taiwan Gold”, and raise their comprehension and identification with the Taiwanese culture.
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( Chien-pin Lai ),( Yong-syuan Chen ),( Tsung-ho Ying ),( Cheng-yen Kao ),( Hui-ling Chiou ),( Shao-hsuan Kao ),( Yi-hsien Hsieh ) 대한신장학회 2023 Kidney Research and Clinical Practice Vol.42 No.4
Background: Mounting evidence indicates that melatonin has possible activity against different tumors. Pazopanib is an anticancer drug used to treat renal cell carcinoma (RCC). This study tested the anticancer activity of melatonin combined with pazopanib on RCC cells and explored the underlying mechanistic pathways of its action. Methods: The 786-O and A-498 human RCC cell lines were used as cell models. Cell viability and tumorigenesis were detected with the MTT and colony formation assays, respectively. Apoptosis and autophagy were assessed using TUNEL, annexin V/propidium io dide, and acridine orange staining with flow cytometry. The expression of cellular signaling proteins was investigated with western blotting. The in vivo growth of tumors derived from RCC cells was evaluated using a xenograft mouse model. Results: Together, melatonin and pazopanib reduced cell viability and colony formation and promoted the apoptosis of RCC cells. Fur thermore, the combination of melatonin and pazopanib triggered more mitochondrial, caspase-mediated, and LC3-II-mediated auto phagic apoptosis than melatonin or pazopanib alone. The combination also induced higher activation of the p38 mitogen-activated protein kinase (p38MAPK) in the promotion of autophagy and apoptosis by RCC cells than melatonin or pazopanib alone. Finally, tu mor xenograft experiments confirmed that melatonin and pazopanib cooperatively inhibited RCC growth in vivo and predicted a possi ble interaction between melatonin/pazopanib and LC3-II. Conclusion: The combination of melatonin and pazopanib inhibits the growth of RCC cells by inducing p38MAPK-mediated mitochon drial and autophagic apoptosis. Therefore, melatonin might be a potential adjuvant that could act synergistically with pazopanib for RCC treatment.
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