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      저자 : ( Hidehiko Komine ) (검색결과 1 건)
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        Orignal Paper : High circulating Levels of oxidized LDL in strength-trained athletes

        ( Seiji Maeda ),( Young Ju Choi ),( Mutsuko Yoshizawa ),( Kai Tanabe ),( Asako Miyaki ),( Yoko Tanabe ),( Hitoshi Shiraki ),( Ryuichi Ajisaka ),( Hidehiko Komine ) 한국운동영양학회 2011 Physical Activity and Nutrition (Phys Act Nutr) Vol.15 No.2

        Oxidized low-density lipoprotein (oxLDL) has been shown to play a major role in the progression of atherosclerosis and cardiovascular disease. Aerobic exercise training has been reported to decrease plasma oxLDL levels. However, until now, there have been no studies regarding the effect of strength exercise training on plasma oxLDL levels. The purpose of this study was to investigate the plasma oxLDL. concentration and antioxidant capacity of plasma in strength-trained athletes. We specifically assessed the total scavenging activity against plasma hydroxyl radical (HO,) and alkoxyl radical (RO,) by using the electron spin resonance (ESR) technique, as both radicals are involved in oxLDL production. The subjects included young strength-trained athletes (SA group; shot put, hammer, javelin throwers, or power lifters; n=9) and sedentary individuals (control group; n=9). We measured plasma oxLDL concentrations and total scavenging activity against HO, and RO. Maximal muscle strength, as assessed by isokinetic tests of the knee and elbow joints and maximal handgrip strength, was significantly greater in the SA group than in the control group. Plasma oxl.DL concentrations were found to be significantly higher in the SA group than in the control group. The total scavenging activity of plasma against HO, and RO. did not differ between the two groups. These results suggest that high-intensity strength training increases plasma oxLDL concentration without upregulating the total scavenging activity against plasma HO, and RO.

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