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Time dependent efficacy change after dilution of the disinfectants against avian influenza virus
장양호,Gwangjick Lee,Jae-Young Song,Hyobi Kim,장병준,최농훈 한국예방수의학회 2015 예방수의학회지 Vol.39 No.2
The efficacy of chemical disinfectants is reduced owing to the inactivation of active ingredients after dilution. This study investigated the effect of time on the efficacy of six different disinfectants, after dilution, against avian influenza virus. When used at the recommended concentration, most disinfectants showed efficacy at a high concentrations in the presence of organic materials immediately after dilution, while sodium dichloroisocyanurate-based products, after dilution, showed reduced efficacy over time at low concentrations in the absence of organic materials. Most disinfectants were neutralized by organic materials; however, this could be compensated for by increasing the product dosage. For successful decontamination in farms, disinfectants should be used at high concentrations in accordance with the manufacturers’ recommendations. Furthermore, the presence of organic materials must be taken into consideration, and diluted disinfectant solution should be prepared no more than a day before use.
( Yang Ho Jang ),( Gwangjick Lee ),( Jae Young Song ),( Hyobi Kim ),( Byung Jun Jang ),( Nong Hoon Choe ) 한국예방수의학회(구 한국수의공중보건학회) 2015 예방수의학회지 Vol.39 No.2
The efficacy of chemical disinfectants is reduced owing to the inactivation of active ingredients after dilution. This study investigated the effect of time on the efficacy of six different disinfectants, after dilution, against avian influenza virus. When used at the recommended concentration, most disinfectants showed efficacy at a high concentrations in the presence of organic materials immediately after dilution, while sodium dichloroisocyanurate-based products, after dilution, showed reduced efficacy over time at low concentrations in the absence of organic materials. Most disinfectants were neutralized by organic materials; however, this could be compensated for by increasing the product dosage. For successful decontamination in farms, disinfectants should be used at high concentrations in accordance with the manufacturers’ recommendations. Furthermore, the presence of organic materials must be taken into consideration, and diluted disinfectant solution should be prepared no more than a day before use.