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기저세포암 및 편평세포암에서 미세혈관밀도와 p53 단백 발현에 관한 연구
어수락,조규성,안호범,김대영,이삼용,조백현 大韓成形外科學會 1999 Archives of Plastic Surgery Vol.26 No.3
Basal cell carcinoma(BCC) and squamous cell carcinoma (SCC) are very prevalent neoplasms of the human skin. Ultraviolet radiation in sunlight is a well-established mutagen of the p53 gene and is one of basal cell carcinoma and squamous cell carcinoma. The newly-formed vascular network is important for neoplasms to grow beyond a size of about 1 ㎣. Recent reports have suggested the hypothesis that a mutant p53 protein is closely related with capillary density. Immumohistochemistry for p53 protein and CD34 was performed in 20 cases of BCCs and 14 SCCs to evaluated the relationship between p53 protein and capillary density. The results were as follows:1. The microvessels stained by CD34 were mainly located in the interface of tumor cells and stroma. 2. There was no difference in the microvessel density according to the histologic types and age of the patients, but a higher microvessel density was noted in male patients. 3. The aggressive BCCs and the less-differentiated SCCs showed higher p53 immunostaining. 4. The mean microvessel density of cases showing strong positive immunostaining of the p53 gene(54.73±17.75) was higher than that of others(39.75±18.30). These results suggested that p53 protein expression and microvessel density are not related to the histologic types and age of the patients, but that differentiation and biologic behavior such as the infiltrating property of tumors and the microvessel density are closely related to p53 protein expression.
Design of a High Dynamic-Range RF ASIC for Anti-jamming GNSS Receiver
Kim, Heung-Su,Kim, Byeong-Gyun,Moon, Sung-Wook,Kim, Se-Hwan,Jung, Seung Hwan,Kim, Sang Gyun,Eo, Yun Seong The Institute of Positioning 2015 Journal of Positioning, Navigation, and Timing Vol.4 No.3
Global Positioning System (GPS) is used in various fields such as communications systems, transportation systems, e-commerce, power plant systems, and up to various military weapons systems recently. However, GPS receiver is vulnerable to jamming signals as the GPS signals come from the satellites located at approximately 20,000 km above the earth. For this reason, various anti-jamming techniques have been developed for military application systems especially and it is also required for commercial application systems nowadays. In this paper, we proposed a dual-channel Global Navigation Satellite System (GNSS) RF ASIC for digital pre-correlation anti-jam technique. It not only covers all GNSS frequency bands, but is integrated low-gain/attenuation mode in low-noise amplifier (LNA) without influencing in/out matching and 14-bit analogdigital converter (ADC) to have a high dynamic range. With the aid of digital processing, jamming to signal ratio is improved to 77 dB from 42 dB with proposed receiver. RF ASIC for anti-jam is fabricated on a 0.18-μm complementary metal-oxide semiconductor (CMOS) technology and consumes 1.16 W with 2.1 V (low-dropout; LDO) power supply. And the performance is evaluated by a kind of test hardware using the designed RF ASIC.
Kim, Eo Jin,Kim, So Ri,Jin Gang, Su,Park, Seung Yong,Han, Young Min,Lee, Yong Chul Wolters Kluwer Health 2015 Medicine Vol.94 No.7
<P><B>Abstract</B></P><P>Small cell lung cancer (SCLC) metastasizes widely, but palatine tonsil is an extremely unusual site for metastasis. Idiopathic pulmonary fibrosis (IPF) is associated with increased risk of lung cancer. However, the most common histological findings among patients of lung cancer with IPF are known as non-SCLC such as adenocarcinoma and squamous cell carcinoma. In addition, the majority of them are located in IPF-associated fibrotic peripheral lesions.</P><P>A 77-year-old man visited for 1-month persistent cough and dyspnea, with inspiratory dry crackles on both lower lung fields and a large oval mass in his throat. Chest computed tomography revealed 2 masses in the left lower lobe, 1 mass in the right upper lobe, and multiple enlarged mediastinal lymph nodes of the lung accompanying with IPF, which were diagnosed as SCLC pathologically. Very interestingly, the tonsillar mass was also confirmed as the metastatic lesion of SCLC. Chemotherapy for SCLC and medical treatment for IPF were applied. However, in following-up, he expired due to respiratory failure by an acute exacerbation of IPF 3 months after the diagnosis.</P><P>In this current report, we describe, for the first time, a case of tonsillar metastasis of SCLC with IPF detected simultaneously in a 77-year-old man.</P>
Kim, Dong-Eog,Kim, Jeong-Yeon,Schellingerhout, Dawid,Ryu, Ju Hee,Lee, Su-Kyoung,Jeon, Sangmin,Lee, Ji Sung,Kim, Jiwon,Jang, Hee Jeong,Park, Jung E.,Kim, Eo Jin,Kwon, Ick Chan,Ahn, Cheol-Hee,Nahrendorf American Heart Association 2017 Stroke Vol. No.
<P>Conclusions-Thromboembolic burden and the efficacy of tPA therapy can be assessed serially, noninvasively, and quantitatively using high-resolution microcomputed tomography and a fibrin-binding nanoparticle imaging agent.</P>
UIP 환자에서 c-Jun N-terminal Kinase (JNK) 활성화에 관한 연구
김기업 ( Kim Gi Eob ),이영목 ( Lee Yeong Mog ),김도진 ( Kim Do Jin ),문승혁 ( Mun Seung Hyeog ),어수택 ( Eo Su Taeg ),김용훈 ( Kim Yong Hun ),박춘식 ( Park Chun Sig ),김현조 ( Kim Hyeon Jo ),염욱 ( Yeom Ug ),황정화 ( Hwang Jeong 대한결핵 및 호흡기학회 2001 Tuberculosis and Respiratory Diseases Vol.51 No.5
양측 흉수를 동반한 난소과자극증후군 (Ovarian Hyperstimulation Syndrome OHSS) 1례
김기업 ( Kim Gi Eob ),한상훈 ( Han Sang Hun ),김도진 ( Kim Do Jin ),윤보라 ( Yun Bo La ),윤현수 ( Yun Hyeon Su ),이영경 ( Lee Yeong Gyeong ),나문준 ( Na Mun Jun ),어수택 ( Eo Su Taeg ),김용훈 ( Kim Yong Hun ),박춘식 ( Park Chun Si 대한결핵 및 호흡기학회 2001 Tuberculosis and Respiratory Diseases Vol.50 No.5
전기 아이론 웨이브 시술온도에 따른 S-웨이브 유지시간, 모발의 물리적 성상과 형태학적 변화
어수연 ( Su Yeon Eo ),김순경 ( Soon Kyoung Kim ),김기영 ( Ki Young Kim ) 한국미용학회 2013 한국미용학회지 Vol.19 No.4
Recently, electronic waving iron is often applied for elegant S-wave formation and hair straight because of easy and simply using procedure. So that, in this study, the S-wave maintenance time, change of the physical properties and morphology in hair were investigated after treatment of the waving iron at 140oC, 160oC and 180oC. The results showed that the elastic S-wave was formed at 160oC and 180oC. Swave became loose quickly in the one hour (11.3~19.5%) to 6 hours (36.5~38.2%), and became loose very slowly from after 12 hours (40.4~41.2%) until 48 hours (48.2~50.1%), and the speed of becoming loose was the lowest at 160oC. The thickness of hair was decreased 12.9% at 140oC, 13.7% at 160oC, and 14.7% at 180oC. The tensile strength was reduced by 14.8% at 140oC, 17.2% at 160oC, 20.1% at 180oC, compared to the tensile strength before the waving iron. The change in the physical properties was the most noticeable at 180oC, which was found to show the most serious damage to hairs. After the waving iron, the thickness of cuticles became thinner as the waving iron temperature higher. And the waving iron at 160oC showed lower damage in observing hair thickness, tensile strength and the thickness and shape of hair cuticles. It is concluded that the desirable maintenance time for elastic S-wave is one hour to 6 hours after waving iron. And the optimum temperature to show natural and glamourous wave and give less damage to hair is at 160oC.