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Quantitative Analysis of IFEP for the Development of Korean High-level Waste Repository
Donghoon Baek,Kibeom Son,Jaekyeon Yang,Gyunyoung Heo,Hyungdae Kim,Kunok Chang 한국방사성폐기물학회 2022 한국방사성폐기물학회 학술논문요약집 Vol.20 No.1
Safety evaluation of high-level radioactive waste disposal facilities including spent nuclear fuel is a very urgent and critical issue, and in order to do so, it is very important to develop a safety case that includes Feature, Event, Process (FEP) analysis, scenario development, and scenario uncertainty evaluation. In the case of Korea, the disposal of spent nuclear fuel is recognized as an unavoidable option, and in the end, Korea’s specific FEP (SFEP) development and safety evaluation according to the scenario should be conducted. Because each country’s situation and environment are different, it is necessary to develop an SFEP based on a generic FEP (International FEP). To this end, an understanding of IFEP is essential. In this study, about 1,000 major terms appearing in the OECD/NEA IFEP are classified to where each of them belongs among F, E, and P, and which FEP each word belongs to, and the correlation between the frequency of occurrence and each term is analyzed. This result will serve as a reference for the results of SFEP analysis such as POSIVA and SKB, which our research team will analyze later. In addition, each term belongs to which academic field, and the most appropriate translation for translating each term into Korean is also described.
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( Jungseopeom ),( Eunjungcho ),( Donghoonbaek ),( Kyungnamlee ),( Kyunghwashin ),( Mihyunkim ),( Kwanghalee ),( Kiukkim ),( Hyekyungpark ),( Yunsungkim ),( Soonkewpark ),( Seongheoncha ),( Minkilee ) 대한결핵 및 호흡기학회 2012 Tuberculosis and Respiratory Diseases Vol.72 No.1
The survival of non-small cell lung cancer (NSCLC) patients with brain metastases is reported to be 3∼6 months even with aggressive treatment. Some patients have very short survival after aggressive treatment and reliable prognostic scoring systems for patients with cancer have a strong correlation with outcome, often supporting decision making and treatment recommendations. A total of one hundred twenty two NSCLC patients with brain metastases who received gamma knife radiosurgery (GKRS) were analyzed. Survival analysis was calculated in all patients for thirteen available prognostic factors and four prognostic scoring systems: score index for radiosurgery (SIR), recursive partitioning analysis (RPA), graded prognostic assessment (GPA), and basic score for brain metastases (BSBM). Results: Age, Karnofsky performance status, largest brain lesion volume, systemic chemotherapy, primary tumor control, and medication of epidermal growth factor receptor tyrosine kinase inhibitor were statistically independent prognostic factors for survival. A multivariate model of SIR and RPA identified significant differences between each group of scores. We found that three-tiered indices such as SIR and RPA are more useful than four-tiered scoring systems (GPA and BSBM). There is little value of RPA class III (most unfavorable group) for the same results of 6-month and 1-year survival rate. Thus, SIR is the most useful index to sort out patients with poorer prognosis. Further prospective trials should be performed to develop a new molecular- and gene-based prognostic index model.
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