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Xiaoyu Li,Dazhong Ma,Xuguang Hu,Qiuye Sun 제어·로봇·시스템학회 2020 International Journal of Control, Automation, and Vol.18 No.2
By utilizing dynamic event-triggered control strategy, this paper deals with consensus problem of a class of heterogeneous leader-following multi-agent systems(MASs) consisting of a high-dimensional leader system but low-dimensional following systems. A kind of observer-based consensus controllers is put forward with a dynamic event-triggered function consisting of the measurement error and a threshold based on the neighbors’ discrete states to reduce unnecessary utilization of limited communication and computation resources. Meanwhile, a dynamic variable is used to generate the event-triggered law using Input-to-State Stability(ISS) criteria. Based on this criteria, the proposed control strategy ensures stability of MASs, which fully reflects of the relationship between the external control inputs of the following systems and the internal states of the leader system and fully considered the influence of disturbances or noises on the MASs. Furthermore, the Zeno behavior for triggering time sequence is excluded. At last, a numerical simulation is provided to demonstrate the feasibility and effectiveness of the theoretical results.
( Ye Tao ),( Dazhong Sun ),( Xinran Ren ),( Yicheng Zhao ),( Hengjian Zhang ),( Tao Jiang ),( Jiyu Guan ),( Yong Tang ),( Wu Song ),( Shuqiang Li ),( Li Wang ) 한국미생물생명공학회 2022 Journal of microbiology and biotechnology Vol.32 No.10
Staphylococcus aureus (S. aureus) infection causes dramatic harm to human health as well as to livestock development. As an important virulence factor, alpha-hemolysin (hla) is critical in the process of S. aureus infection. In this report, we found that bavachin, a natural flavonoid, not only efficiently inhibited the hemolytic activity of hla, but was also capable of inhibiting it on transcriptional and translational levels. Moreover, further data revealed that bavachin had no neutralizing activity on hla, which did not affect the formation of hla heptamers and exhibited no effects on the hla thermal stability. In vitro assays showed that bavachin was able to reduce the S. aureus-induced damage of A549 cells. Thus, bavachin repressed the lethality of pneumonia infection, lung bacterial load and lung tissue inflammation in mice, providing potent protection to mice models in vivo. Our results indicated that bavachin has the potential for development as a candidate hla inhibitor against S. aureus.
Dengfeng Yang,Li’ang Cao,Ce Yang,Dazhong Lao,Harold Sun 대한기계학회 2020 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.34 No.6
In this work, the influence of thickness and solidity of guide vane on the unsteady flow of a radial inflow turbine with variable nozzle has been numerically studied. Three vanes with the thickness changes from 0.3 to 0.1 and the solidity changes from 1.43 to 2.86, were chosen for this study. By investigating the unsteady flow field, it is found that the vane with low thickness and high solidity (vane B) can reduce shock by 75 % compared to the vane with high thickness and low solidity (base model); meanwhile, it can also mitigate the nozzle endwall leakage flow thus improves the flow uniformity of rotor inlet. As the intensity of shock and nozzle leakage flow were mitigated, the aerodynamic loading fluctuation of rotor blade can be weakened effectively, which will lead to improved rotor blades forced response. However, at small opening, vane B shows about 0.5 % lower efficiency than the base model; at large open condition, the efficiency degradation of vane B is up to 1.4 %. Therefore, there is a trade-off between the efficiency and forced response when choosing the nozzle vane solidity and thickness.