Evolution of Diastolic Dysfunction in Patients with Coronary Slow Flow Phenomenon and Acute Non-ST Segment Elevation Myocardial Infarction

Ahmed El Zayat,Mahmoud Abdelaziz,Ahmed Yousry,Ismail Ibrahim 한국심초음파학회 2021 Journal of Cardiovascular Imaging (J Cardiovasc Im Vol.29 No.4

BACKGROUND: Diastolic function has been reported to be impaired in many patients with coronary slow flow phenomenon (CSFP). CSFP has broad spectrum of clinical presentations, including non-ST elevation myocardial infarction (NSTEMI). We sought to study the short-term evolution of diastolic function in CSFP patients presenting with NSTEMI. METHODS: This study included 92 patients with CSFP and acute NSTEMI. Conventional echocardiography Doppler imaging and tissue Doppler echocardiography imaging were used to evaluate diastolic function during index NSTEMI and after 3 months. RESULTS: Mean age of study patients was 45.7 ± 6.8 years. The prevalence of diastolic dysfunction (DD) at baseline was 69 patients (75%) and 28 patients (30.4%) at 3 months, p < 0.001. Various diastolic function indices showed significant improvement from baseline to 3 months follow-up. E/Em was 17.32 ± 3.41 at baseline compared to 12.41 ± 5.58 at 3 months, p = 0.039. Septal e′ velocity was 5.67 ± 4.56 cm/s at baseline compared to 7.78 ± 3.22 cm/s at 3 months, p = 0.023. Medications used were not significantly different between those with improved versus unimproved DD. CONCLUSIONS: Diastolic function seems to improve over short-term follow-up in patients with CSFP presenting with NSTEMI. This could reflect a transient worsening during acute NSTEMI.

Using XFEM Technique to Predict the Effect of Default on the Damage of Steel Pipe Reduced-Connection Under Bending and Pressure Loading

Abdelaziz Ahmed-Bensoltane,Mohamed Mokhtari,Habib Benzaama,Khaled Samet,Hamza Benrouba,Elamine Abdelouahed 한국강구조학회 2023 International Journal of Steel Structures Vol.23 No.1

Over the years of service and by effect of their typical geometries, pressurized tubular structures assembled by a connection of an elbow or a reduced Tee or other, are much more stressed compared to straight tubes at significant normal and tangential stresses. With the presence of faults, these connections are subsequently largely responsible for their damage. Damage to an X60 Grade 8 ”x4” steel tube Reduced Tee connection element under oriented loading and internal pressure with or without the presence of a defect was investigated in this work. Because of these advantages and in order to present the propagation of a crack, we opted for the use of the XFEM technique (extend finite element method). Numerical prediction using the ABAQUS compute code set out to assess dependent parameters such as location and type of fault as well as mode and accumulated load level. Indeed, the loading mode clearly showed a large difference between the response down to the level of damage. These results are presented by curves which present both the response of a structure in force-displacement and the crack propagation (initiation and critical length). The default location in the structure at the connection joint is oriented according to the loading mode. The different situations analyzed affect all possible cases that the element of the reduced Tee may undergo. The type of defect is related by its location according to the thickness in the form of a metal tear. This damage analysis shows that the parameters studied in the structure clearly condition the level and mode of failure as well as their response to damage.

Survey on Network Virtualization Using OpenFlow: Taxonomy, Opportunities, and Open Issues

( Ahmed Abdelaziz ),( Tan Fong Ang ),( Mehdi Sookhak ),( Suleman Khan ),( Athanasios Vasilakos ),( Chee Sun Liew ),( Adnan Akhunzada ) 한국인터넷정보학회 2016 KSII Transactions on Internet and Information Syst Vol.10 No.10

The popularity of network virtualization has recently regained considerable momentum because of the emergence of OpenFlow technology. It is essentially decouples a data plane from a control plane and promotes hardware programmability. Subsequently, OpenFlow facilitates the implementation of network virtualization. This study aims to provide an overview of different approaches to create a virtual network using OpenFlow technology. The paper also presents the OpenFlow components to compare conventional network architecture with OpenFlow network architecture, particularly in terms of the virtualization. A thematic OpenFlow network virtualization taxonomy is devised to categorize network virtualization approaches. Several testbeds that support OpenFlow network virtualization are discussed with case studies to show the capabilities of OpenFlow virtualization. Moreover, the advantages of popular OpenFlow controllers that are designed to enhance network virtualization is compared and analyzed. Finally, we present key research challenges that mainly focus on security, scalability, reliability, isolation, and monitoring in the OpenFlow virtual environment. Numerous potential directions to tackle the problems related to OpenFlow network virtualization are likewise discussed

Interferon-γ and Interleukin-10 Gene Polymorphisms are not Predictors of Chronic Hepatitis C (Genotype-4) Disease Progression

Bahgat, Nermine Ahmed,Kamal, Manal Mohamed,Abdelaziz, Ashraf Omar,Mohye, Mohamed Ahmed,Shousha, Hend Ibrahim,ahmed, Mae Mohamed,Elbaz, Tamer Mahmoud,Nabil, Mohamed Mahmoud Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.12

Immunoregulatory cytokines have an influence on hepatitis C virus (HCV) infection outcome. This study aimed to determine whether single nucleotide polymorphisms (SNP) in IFN- ${\gamma}$ and IL-10 genes are associated with susceptibility and/or are markers of prognosis regarding chronic hepatitis C outcomes. IFN ${\gamma}$ (+874T/A) and IL-10 (-1082G/A) genotypes were determined in 75 HCV genotype 4 patients with different disease severities (chronic hepatitis, n=25, liver cirrhosis and hepatocellular carcinoma (HCC) on top of liver cirrhosis, n=50) and 25 healthy participants using allele-specific polymerase chain reaction. No statistical differences in allele or genotype distributions of IFN ${\gamma}$ and IL-10 genes were detected between patients and controls or between patientgroups. No significant difference in the frequency of IL-10 SNP at position -1082 or IFN-${\gamma}$ at position +874T/A was found between chronic HCV genotype 4 and with progression of disease severity in liver cirrhosis or HCC. In conclusion; interferon-${\gamma}$ and interleukin-10 gene polymorphisms are not predictors of disease progression in patients with chronic hepatitis C (Genotype-4).

Survival and Prognostic Factors for Hepatocellular Carcinoma: an Egyptian Multidisciplinary Clinic Experience

Abdelaziz, Ashraf Omar,Elbaz, Tamer Mahmoud,Shousha, Hend Ibrahim,Ibrahim, Mostafa Mohamed,El-Shazli, Mostafa Abdel Rahman,Abdelmaksoud, Ahmed Hosni,Aziz, Omar Abdel,Zaki, Hisham Atef,Elattar, Inas An Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.9

Background: Hepatocellular carcinoma (HCC) is a dismal tumor with a high incidence, prevalence and poor prognosis and survival. Management of HCC necessitates multidisciplinary clinics due to the wide heterogeneity in its presentation, different therapeutic options, variable biologic behavior and background presence of chronic liver disease. We studied the different prognostic factors that affected survival of our patients to improve future HCC management and patient survival. Materials and Methods: This study is performed in a specialized multidisciplinary clinic for HCC in Kasr El Eini Hospital, Cairo University, Egypt. We retrospectively analyzed the different patient and tumor characteristics and the primary mode of management applied to our patients. Further analysis was performed using univariate and multivariate statistics. Results: During the period February 2009 till February 2013, 290 HCC patients presented to our multidisciplinary clinic. They were predominantly males and the mean age was $56.5{\pm}7.7years$. All cases developed HCC on top of cirrhosis that was mainly due to HCV (71%). Most of our patients were Child-Pugh A (50%) or B (36.9%) and commonly presented with small single lesions. Transarterial chemoembolization was the most common line of treatment used (32.4%). The overall survival was 79.9% at 6 months, 54.5% at 1 year and 22.4% at 2 years. Serum bilirubin, site of the tumor and type of treatment were the significant independent prognostic factors for survival. Conclusions: Our main prognostic variables are the bilirubin level, the bilobar hepatic affection and the application of specific treatment (either curative or palliative). Multidisciplinary clinics enhance better HCC management.

Single puncture combined lumbar erector spinae plane and quadratus lumborum block (SEQ block) in acetabular fracture surgeries: randomized clinical trial

Ahmed Aly Mahmoud Moustafa,Moustafa Moustafa Abdelaziz,Alabd Ahmad Samir 대한마취통증의학회 2023 Anesthesia and pain medicine Vol.18 No.4

Versatile Roles of Microbes and Small RNAs in Rice and Planthopper Interactions

Abdelaziz Mansour,Mannaa Mohamed Ibrahim Mohamed Ahmed,Omar Hewedy,Mostafa G. Ali,정혜정,서영수 한국식물병리학회 2022 Plant Pathology Journal Vol.38 No.5

Planthopper infestation in rice causes direct and indirect damage through feeding and viral transmission. Host microbes and small RNAs (sRNAs) play essential roles in regulating biological processes, such as metabolism, development, immunity, and stress responses in eukaryotic organisms, including plants and insects. Recently, advanced metagenomic approaches have facilitated investigations on microbial diversity and its function in insects and plants, highlighting the significance of microbiota in sustaining host life and regulating their interactions with the environment. Recent research has also suggested significant roles for sRNA-regulated genes during rice–planthopper interactions. The response and behavior of the rice plant to planthopper feeding are determined by changes in the host transcriptome, which might be regulated by sRNAs. In addition, the roles of microbial symbionts and sRNAs in the host response to viral infection are complex and involve defense-related changes in the host transcriptomic profile. This review reviews the structure and potential functions of microbes and sRNAs in rice and the associated planthopper species. In addition, the involvement of the microbiota and sRNAs in the rice–planthopper–virus interactions during planthopper infestation and viral infection are discussed.

Early assessment of aspiration risk in acute stroke by fiberoptic endoscopy in critically ill patients

Mohamed Saad Abdelaziz Elsyaad,Akram Muhammad Fayed,Mohamed Mostafa Abdel Salam Megahed,Nesrine Hazem Hamouda,Ahmed Moustafa Elmenshawy 대한중환자의학회 2022 Acute and Critical Care Vol.37 No.3

Background: Fiberoptic endoscopic evaluation of swallowing (FEES) has been recommended to assess aspiration in stroke. This study aimed to determine the diagnostic and prognostic roles of FEES in the early assessment of aspiration, intensive care unit (ICU) stay and mortality in acute stroke patients.Methods: Fifty-two patients with acute stroke admitted to the Alexandria Main University Hospital were included. Complete examinations and assessment of aspiration using the 8-point penetration-aspiration scale (PAS) with FEES protocol were performed.Results: The patients were classified into three groups: normal with no or low risk of aspiration (n=15, 27.3%; PAS level 1), low to moderate risk (n=8, 14.5%; PAS level 2–4), and high risk (n=32, 58.2%; PAS ≥5). There was high incidence of aspiration pneumonia, prolonged ICU stay, and mortality in both moderate- and high-risk groups (P=0.001, P<0.001, and P<0.001, respectively). The PAS score predicted aspiration pneumonia (hospital-acquired pneumonia) with sensitivity and specificity of 80.0% and 76.0%, respectively (negative predictive value [NPV], 76.0; positive predictive value [PPV], 80.0; 95% confidence interval [CI], 0.706–0.940) and mortality with sensitivity and specificity of 88.46% and 68.97% (NPV, 87.0; PPV, 71.9; 95% CI, 0.749–0.951). The PAS score could predict the length of ICU stay with sensitivity and specificity of 70.21% and 87.50, respectively (NPV, 33.3; PPV, 97.1; 95% CI, 0.605–0.906).Conclusions: The standard FEES protocol using PAS score is a useful tool to assess aspiration in acute stroke patients and could be used to predict length of ICU stay and mortality.

Occurrence of the Root-Knot Nematode species in Vegetable Crops in Souss Region of Morocco

Soukaina Janati,Abdellah Houari,Ahmed Wifaya,Adil Essarioui,Abdelaziz Mimouni,Abderrahim Hormatallah,Mohamed Sbaghi,Abdelfattah A. Dababat,Fouad Mokrini 한국식물병리학회 2018 Plant Pathology Journal Vol.34 No.4

Root-knot nematodes ‘Meloidogyne spp’ are the most destructive group of plant parasitic nematodes causeing serious losses in vegetables crops and this damages worsened when crops grown under greenhouses conditions. In this sutdy, the distribution and characterization of root-knot nematode species collected from the Souss region of Morocco where vegetables crops intensively cultivated were determined by using both morphological and molecular tools. Out of the 110 samples collected from different greenhouses 91 (81.7%) were found to be infested with root-knot nematodes. Thirty-seven populations of root-knot nematodes were morphologically identified based on perineal patterns as well as molecularlly using species-specific primers. The obtained results indicated that Meloidogyne javanica and M. incognita were identified in 86.4% and 13.5% of the total populations, respectively. The lowest incidence of root-knot nematodes (64%) was found in Toussous, whereas the highest frequencies of 100% and 90% were detected in Taddart and Biogra, respectively. As the majority of the samples have been infested with Meloidogyne species; this indicates that there is an urgent need to provide farmers with a proper control strategy.

Hydrothermal alterations of the Bou Azzer East Co-Ni-As-Au deposits (central Anti-Atlas, Morocco)

Muhammad Souiri,Mohamed Aissa,Ahmed H. Ahmed,Mohammed El Azmi,Hafid Mezougane,Azizi Moussaid,Abdelaziz El Basbas 한국지질과학협의회 2021 Geosciences Journal Vol.25 No.5

The polymetallic Co, Ni, Cu, Zn, Au and Ag deposits of Bou Azzer East is linked to Bou Azzer ophiolite located in the Central Anti Atlas. The ultramafic rocks are strongly deformed and altered by serpentinization, carbonatization and silicification. The mineralization is hosted by quartz, quartz-carbonate and/or chlorite veins, intimately associated with the serpentinite-quartz diorite contact. The description of alteration phenomena as mineralizing events, especially in Co-Ni arsenides and precious metals Au-Ag is realized. The petro-mineralogical and geochemical studies of the mineralized structures and their surrounding host rocks reveal several types of alterations that developed a lateral zoning at the serpentinite level, with formations of silica-, talc-, carbonate-, and chlorite-rich serpentinites. Nearly all primary silicate minerals have been replaced by serpentine minerals, leaving only relics of primary olivine and chromian spinel. The presence of antigorite dominated serpentinites indicates that the Bou Azzer ultramafic sequence was hydrated at relatively high temperature between 200 and 350 °C. In agreement with fluid inclusions study and the estimated temperatures from the chemical composition of chlorites (220–320 °C), which showed an evolution from ferrous chlorites (pychnochlorite and ripidolite) to magnesian chlorites (penninite and clinochlore). The altered zone is characterized by high metal contents of As, Co, Mo, Ag and Au in the silica-rich serpentinite and Cr, Cu, Zn and Pb in the carbonate-rich serpentinite. The enrichment in these elements result from the action of brines with a high Si content and fluids rich in Ca, Mg and CO2 on serpentinized peridotite, respectively. The chloritite breccia developed mainly in shear zones also shows elevated levels in As, Co, Mo, Ag and Au, buffered by the interaction between the fluid and the surrounding rocks.