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- 저자 : Wael (검색결과 108 건)
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Wael Nassar,Mervat El-Ansary,Dina Sabry,Mostafa A. Mostafa,Tarek Fayad,Esam Kotb,Mahmoud Temraz,Abdel-Naser Saad,Wael Essa,Heba Adel 한국생체재료학회 2016 생체재료학회지 Vol.20 No.3
Background: Bio-products from stem/progenitor cells, such as extracellular vesicles, are likely a new promising approach for reprogramming resident cells in both acute and chronic kidney disease. Forty CKD patients stage III and IV (eGFR 15–60 mg/ml) have been divided into two groups; twenty patients as treatment group “A” and twenty patients as a matching placebo group “B”. Two doses of MSC-derived extracellular vesicles had been administered to patients of group “A”. Blood urea, serum creatinine, urinary albumin creatinine ratio (UACR) and estimated glomerular filtration rate (eGFR) have been used to assess kidney functions and TNF-α, TGF-β1 and IL-10 have been used to assess the amelioration of the inflammatory immune activity. Results: Participants in group A exhibited significant improvement of eGFR, serum creatinine level, blood urea and UACR. Patients of the treatment group “A” also exhibited significant increase in plasma levels of TGF-β1, and IL-10 and significant decrease in plasma levels of TNF-α. Participants of the control group B did not show significant improvement in any of the previously mentioned parameters at any time point of the study period. Conclusion: Administration of cell-free cord-blood mesenchymal stem cells derived extracellular vesicles (CF-CBMSCs-EVs) is safe and can ameliorate the inflammatory immune reaction and improve the overall kidney function in grade III-IV CKD patients.
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Wael Basri 대한산업공학회 2019 Industrial Engineeering & Management Systems Vol.18 No.3
The purpose of the study is to investigate the influential factors for organizational performance at Saudi food companies. The study investigated the relationship between information system usage, their efficiency and effectiveness, top management support and technical resources as determinants of performance of firms. The moderating role of knowledge management was investigated between the relationships of constructs. The study examined the relationship between constructs and examined moderating effect. The data was collected through questionnaire from Saudi food companies. The data was analyzed by using SMART-PLS, measurement model and structural equation model was used for analyzing data and determine the relationships. The study found positive significant relationship between direct links, but moderating effect between top management support and knowledge management was rejected on the basis of statistical indicators. The study explains the relationships for determination of organizational performance, the study suggests to invest on information system, encourage support from top management and technical resources. Direct effect of knowledge management and moderating role is also explained in the study which serves as contribution in the body of knowledge.
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Free Latismus Dorsi Muscle Flap with a Flow-Through Technique for Lower Limb Salvage
Wael M. Ayad,Abdelnaser Hamdi Mohammed,Hany M. Ismail,Mohamed Osama Ouf,Amr M. Elbatawy 대한수부외과학회 2019 대한수부외과학회지 Vol.24 No.2
Purpose: The lower limb injuries still one of the devastating problems in surgical practice. Complex defects may affect one major vessel that supplies the distal portion of the leg and foot. The use of the flow-through technique is a very useful tool for sure vascularization of the flap and revascularization of the distal limb at the same time. The aim of this study was to evaluate the advantages of the use of the flow-through technique for lower limb reconstruction.Methods: This retrospective study was including 15 patients complaining of post-traumatic leg and/or foot defects. Free latissimus muscle transfer with the flow-through technique was done for lower limb reconstruction. The subscapular ar-tery was anastomosed to the proximal segment of the limb vessel and the circumflex scapular artery anastomosed to the distal segment of the limb vessel. Follow-up was for six months.Results: Patients were followed for 6 months. All flaps were survived and there were no anastomotic complications.Conclusion: The use of the flow-through technique is a very useful tool for vascularization of the flap and revasculariza-tion of the distal limb at the same time.
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Structural Behaviour of Polystyrene Foam Lightweight Concrete Beams Strengthened with FRP Laminates
Wael M. Montaser,Ibrahim G. Shaaban,Amr H. Zaher,Sadaqat U. Khan,Mustafa N. Sayed 한국콘크리트학회 2022 International Journal of Concrete Structures and M Vol.16 No.6
Lightweight concrete (LWC) is one of the most important building materials nowadays. Many research studies were focused on LWC produced using lightweight aggregates. However, limited work was cited for LWC produced using polystyrene beads. In this study, LWC beams strengthened with carbon fibre reinforced polymer (CFRP) and glass fibre reinforced polymer (GFRP) were experimentally tested to investigate the improvement in their flexural and shear behaviours. LWC in this investigation was achieved by partial replacement of normal aggregate by polystyrene beads and resulted in approximately 30% less weight compared to Normal weight concrete. Fourteen Reinforced Concrete (RC) LWC beams of 100 mm by 300 mm cross section having an overall length of 3250 mm were tested under four-point bending. These beams were designed, detailed, and tested to obtain flexural and shear mode of failure. These beams were divided into two groups based on the intended failure mode. In each group, six beams were strengthened using CFRP and GFRP laminates, while the remaining one beam was used as control. The tested parameters were the type of FRP, the width of the laminates used in shear strengthening, and the number of layers used in flexural strengthening. It was found that strengthening of LWC beams using CFRP and GFRP layers resulted in increasing the loading capacity and decreasing deflection as compared to control. The strengthening with CFRP and GFRP is also suitable in reducing the crack width and crack propagation which is more significant in LWC beams. The experimental results were also compared with the expressions in codes for forecasting the strength of LWC beams and it was that these expressions are compatible with the experimental results.
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Sidewalk Gaseous Pollutants Estimation Through UAV Video-based Model
Wael Omar,Impyeong Lee 대한원격탐사학회 2022 大韓遠隔探査學會誌 Vol.38 No.1
As unmanned aerial vehicle (UAV) technology grew in popularity over the years, it was introduced for air quality monitoring. This can easily be used to estimate the sidewalk emission concentration by calculating road traffic emission factors of different vehicle types. These calculations require a simulation of the spread of pollutants from one or more sources given for estimation. For this purpose, a Gaussian plume dispersion model was developed based on the US EPA Motor Vehicle Emissions Simulator (MOVES), which provides an accurate estimate of fuel consumption and pollutant emissions from vehicles under a wide range of user-defined conditions. This paper describes a methodology for estimating emission concentration on the sidewalk emitted by different types of vehicles. This line source considers vehicle parameters, wind speed and direction, and pollutant concentration using a UAV equipped with a monocular camera. All were sampled over an hourly interval. In this article, the YOLOv5 deep learning model is developed, vehicle tracking is used through Deep SORT (Simple Online and Realtime Tracking), vehicle localization using a homography transformation matrix to locate each vehicle and calculate the parameters of speed and acceleration, and ultimately a Gaussian plume dispersion model was developed to estimate the CO, NOx concentrations at a sidewalk point. The results demonstrate that these estimated pollutants values are good to give a fast and reasonable indication for any near road receptor point using a cheap UAV without installing air monitoring stations along the road.
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Strength Prediction of Corbels Using Strut-and-Tie Model Analysis
Wael Kassem 한국콘크리트학회 2015 International Journal of Concrete Structures and M Vol.9 No.2
A strut-and-tie based method intended for determining the load-carrying capacity of reinforced concrete (RC) corbels is presented in this paper. In addition to the normal strut-and-tie force equilibrium requirements, the proposed model is based on secant stiffness formulation, incorporating strain compatibility and constitutive laws of crackedRC.The proposed method evaluates the load-carrying capacity as limited by the failure modes associated with nodal crushing, yielding of the longitudinal principal reinforcement, as well as crushing or splitting of the diagonal strut. Load-carrying capacity predictions obtained fromthe proposed analysis method are in a better agreementwith corbel test results of a comprehensive database, comprising 455 test results, compiled from the available literature, than other existing models for corbels. This method is illustrated to provide more accurate estimates of behaviour and capacity than the shear-friction based approach implemented by the ACI 318-11, the strut-and-tie provisions in different codes (American, Australian, Canadian, Eurocode and New Zealand).
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Wael Nabha,Young-Min Hong,Jin-Hyoung Cho,Hyeon-Shik Hwang 대한치과교정학회 2014 대한치과교정학회지 Vol.44 No.5
Objective: The aim of this study was to assess artifacts induced by metallic restorations in three-dimensional (3D) dental surface models derived by cone-beam computed tomography (CBCT). Methods: Fifteen specimens, each with four extracted human premolars and molars embedded in a plaster block, were scanned by CBCT before and after the cavitated second premolars were restored with dental amalgam. Five consecutive surface models of each specimen were created according to increasing restoration size: no restoration (control) and small occlusal, large occlusal, disto-occlusal, and mesio-occluso-distal restorations. After registering each restored model with the control model, maximum linear discrepancy, area, and intensity of the artifacts were measured and compared. Results: Artifacts developed mostly on the buccal and lingual surfaces. They occurred not only on the second premolar but also on the first premolar and first molar. The parametric values increased significantly with increasing restoration size. Conclusions: Metallic restorations induce considerable artifacts in 3D dental surface models. Artifact reduction should be taken into consideration for a proper diagnosis and treatment planning when using 3D surface model derived by CBCT in dentofacial deformity patients.
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Wael M. Elsaed,Raouf Fekry Bedeer,Mohamed Ahmed Eladl 대한해부학회 2018 Anatomy & Cell Biology Vol.51 No.1
Cimetidine is an H2 receptor antagonist that has an antiandrogenic effect. It intervenes with the conversion of testosterone into estrogen in the Sertoli cells with accompanying testicular structural changes. In the present study, the microscopic and the ultrastructural changes induced by cimetidine and the effect of vitamin B12 as a protective agent on rat testes were studied. Immunoexpression of estrogen receptor β (ERβ) in testes was evaluated. Twenty-four adult male rats were divided into four groups: control, cimetidine-treated, vitamin B12 treated, and combined cimetidine and vitamin B12 treated. The experimental rats were administered with cimetidine and/or vitamin B12 for 52 days. Group II rats showed marked atrophy of the seminiferous tubules with a significant increase in tubular diameter and decrease in the tubular luminal and epithelial areas. Ultrastructure of this group showed irregular Sertoli cells with basal cytoplasmic vacuolation and significantly thickened basement membrane. ERβ immunoexpression was similar to controls. Group III rats showed near normal seminiferous tubular structures with minimal cellular alterations and the immunoreactivity of the testicular sections was very close to normal. However, group IV rats showed markedly immunopositive detached cells, spermatids, and primary spermatocytes. Cimetidine interferes with the control of spermatogenesis as evidenced by microscopic and ultrastructural studies and affection of ERβ receptors and vitamin B12 has a protective action against this harmful effect.
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