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        Trends in incidence and survival outcome of epithelial ovarian cancer: 30-year national population-based registry in Taiwan

        Ying-Cheng Chiang,Chi-An Chen,Chun-Ju Chiang,Tsui-Hsia Hsu,Ming-Chieh Lin,San-Lin You,Wen-Fang Cheng,Mei-Shu Lai 대한부인종양학회 2013 Journal of Gynecologic Oncology Vol.24 No.4

        Objective: To investigate the changes of incidence and prognosis of epithelial ovarian cancer in thirty years in Taiwan. Methods: The databases of women with epithelial ovarian cancer during the period from 1979 to 2008 were retrieved from the National Cancer Registration System of Taiwan. The incidence and prognosis of these patients were analyzed. Results: Totally 9,491 patients were included in the study. The age-adjusted incidences of epithelial ovarian cancer were 1.01, 1.37, 2.37, 3.24, 4.18, and 6.33 per 100,000 person-years, respectively, in every 5-year period from 1979 to 2008. The age-specific incidence rates increased especially in serous, endometrioid and clear cell carcinoma, and the age of diagnosis decreased from sixty to fifty years old in the three decades. Patients with mucinous, endometrioid, or clear cell carcinoma had better long-term survival than patients with serous carcinoma (log rank test, p<0.001). Patients with undifferentiated carcinoma or carcinosarcoma had poorer survival than those with serous carcinoma (log rank test, p<0.001). The mortality risk of age at diagnosis of 30-39 was significantly higher than that of age of 70 years or more (test for trend, p<0.001). The mortality risk decreased from the period of 1996-1999 (hazard ratio [HR], 0.90; p=0.054) to the period after 2000 (HR, 0.74; p<0.001) as compared with that from the period of 1991-1995. Conclusion: An increasing incidence and decreasing age of diagnosis in epithelial ovarian cancer patients were noted. Histological type, age of diagnosis, and treatment period were important prognostic factors for epithelial ovarian carcinoma.

      • 中文教與學處理學生學習差異的原則和策略

        Tse Shek Kam,Wong Man Ying,Laing Victor,Wu Kam Fong,Tsui Pik Fong,To Heiken,Lam Lu Sai 단국대학교 한문교육연구소 2020 International Han-character Education Research Vol.3 No.1

        홍콩에는 예부터 지금까지 파키스탄, 인도, 네팔 등에서 온 이민들을 포함하여, 비중국어권 아동들이 적지 않다. 평등교육의 이념을 표방하는 홍콩평등기회위원회(香港平等機會委員會)는 비중국어권 학습자들이 중국어권 학습자들과 같은 학교에서 학습하기를 건의하여 그들이 최대한 빠른 시일 내에 홍콩 사회로 융화되게 하려 하였다. 이로 인해, 비중국어권 아동들은 홍콩 현지의 일반 유치원을 다니게 되었는데, 홍콩의 교육 관할 당국도 적지 않은 자원을 투입하여 이들이 현지 교육과정에 적응할 수 있도록 협조하였으나, 그 효과를 즉각적으로 확인할 수는 없었다. 그 중 가장 큰 문제는 학습의 차이를 처리하는 것이었다. 비중국어권 아동들의 중국어 실력은 모국어 수준에 미치지는 못했다. 이들이 중국어권 아동들과 함께 중국어 수업에 참여할 때 적잖은 어려움이 발행했다. 또한, 비중국어권 아동들의 성장 배경도 각기 달랐다. 신이민자 가정의 아동도 있고, 현지에서 출생한 소수 민족 아동도 있어, 이러한 학습자 사이의 중국어 수준의 차이도 존재했다. 이밖에도 소수민족과 홍콩의 문화적 차이 또한 매우 커서 모든 교사와 아동은 ‘학습’과 ‘교수’ 두 측면에서 모두 여러 가지 차이로 인해 발생하는 문제들을 처리해야 했다. 이처럼 비중국어권 학습자들이 홍콩에서 중국어를 배우는 것은 매우 쉽지 않았다. 상술한 문제들을 해결하기 위해서 경마회 자선기금 및 다섯 단체의 공영교육 사회복지기구는 「경마회의 재밌는 중국어 배우기(賽馬會(有)友趣學中文)」 라는 프로젝트를 추진하여, 중국어를 모국어로 갖지 않는 학습자들이 효과적으로 중국어 학습 하여 빠르게 사회에 융화되도록 도왔다. 본 프로 젝트는 수준별 교육과정, 수준별 교재, 수준별 학습법, 수준별 교구, 수준별 평가와 다층적 교학법을 설계하고 지원하여 학습 차이에서 생기는 어려움을 해결하는 데 도움을 주었다. 본고에서는 연구 이론과 설계, 데이터 수집 및 연구 결과를 상세히 서술하고, 효과적인 사례에 대해 상세하게 서술하려고 한다. 이러한 연구 성과는 세계 각지에 광범위하게 적용될 수 있을 것이다. The majority of non-Chinese speaking (NCS) young students are studying in mainstream kindergartens. They are of ethnic groups, for instance, Pakistani, Indian, and Nepalese, who are new immigrants or offspring of immigrants in the past. The Equal Opportunities Commission encourages NCS students to study together with Chinese speaking students, for the sake of social inclusion in the long run. In recent years, the Education Bureau has allocated more resources in supporting NCS students for early adaption to the local education system. However, its effect is not predominant. It is believed that managing individual learning differences is one of the major challenges. NCS students is generally lagging behind those with Chinese as their mother tongue in the Chinese proficiency. Therefore, problems and complications arise as the result of the two groups of students studying in the same environment. Dissimilarities exist even among NCS students, some are new immigrants while some are born in Hong Kong. While there are obvious cultural differences between ethnic minorities and local Hong Kong students, teachers face challenges in handling these disparities. NCS students learning Chinese in Hong Kong is not an easy task. Regarding all these above, The Hong Kong Jockey Club Charities Trust in collaboration with three universities and two social welfare organizations have initiated the “C-for-Chinese@JC” project. It supported NCS students learning Chinese, as well as facilitated early social inclusion. The project developed differentiated school-based curriculum, differentiated teaching and learning materials, differentiated pedagogies and assessment, and varied support measures to kindergartens. Language development of non-Chinese speaking kindergarteners was tracked longitudinally in each of their pre-school years that composed of four language assessments. Significant improvement of language learning results was observed during the three years, which proved the effects of differentiate teaching and learning system. The system is able to alleviate the learning difficulties of NCS preschoolers and bridge the learning differences. This paper detailed research theories and design, data collection, research findings, and analysis of successful cases. The findings of this research could be applied in different settings internationally and be globally referenced.

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      • KCI등재

        Temperature-dependent development and life history of Oligonychus litchii (Acari: Tetranychidae), on wax apple

        Wen-Hua Chen,Chao-Yu Li,Tsui-Ying Chang 한국응용곤충학회 2016 Journal of Asia-Pacific Entomology Vol.19 No.1

        The litchi spider mite Oligonychus litchii Lo & Ho is one of the major pests of fruit crops in Taiwan. This study investigated the life history of the litchi spider mite on wax apple (Syzygium samarangense Merr. & Perry) at five constant temperatures (16, 20, 25, 30, and 32 °C) under 70 ± 5% RH and a 12L:12D photoperiod. Ninetyfive percent of the eggs hatched at 20, 25, and 30 °C, respectively. The entire developmental period was 40.3 days at 16 °C and only 9.3 days at 32 °C. The low developmental threshold temperature for development fromegg to adult was 10.1 °C, and the effective accumulated temperature was 197.5 degree–days (DD). Unmated female mites had the longest life span although the oviposition period shortened as temperature increased. Mated female mites produced significantly more eggs than unmated females. At most, a mated female could produce an average of 3.5 eggs per day at 25 °C and a maximum of 60.3 eggs over the entire oviposition period at 20 °C. Unmated females exclusively produce male offspring, indicating that litchi spider mites are arrhenotokous. At 25 °C, the intrinsic rate of increase (r) was 0.1610 day−1, the net reproductive rate (R0) was 19.58 offspring, the finite rate of increase (λ) was 1.1747 day−1, and the mean generation time (T) was 18.50 days. The results obtained in this study provide useful information to aid in the development of phenological models for pest monitoring programs of O. litchii in Taiwan.

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