유치원 敎師職의 專門性에 관한 考察

盧公根 論文集 1982 論文集 Vol.3 No.-

The necessity of Kindergarten education is rising to the high tide as we realize the importance of infants education. In kindergarten teachers ability is largely stressed so that the teaching could be done effectively. In this study, Professional characteristics of kindergasten teachers are cleared to set up the true image of kindergarten educators. Distribution of guestionaire to kindergarten teachers who are in the first line and research on related booklets were used simultaneously for this study. Questionairs distributed dates were Oct. 1 - 20, 1980. Recovered guestionaires were 210 and showed collected rate of 60 percent. In handling the statistics, response was conversed into percentage and occasionally weight secure was given to get precedence. Facts obtained from the Study: 1. Professional Characteristics can be embodied, which help emphasize the unique roles of kindergarten teachers. 2. Relay of childrens socialization is rather a heavier role of kindergarten teachers than to give the necessary lessons (explicit curriculum) taught in kindergarten. 3. Factors preventing those distinctive features of teaching in kindergarten are destined, in general derived from social, systematic problems and also from conventionality. 4. Many of kindergarten teachers become incidentaily, however they come to admit the importance of infants, education through direct experience and tend to hold the job even though they are paid low. 5. A large portion of 83 percent among kindergarten teachers tell "Payment is low" and feel that "they are not respected from the society." These make the job unattractive all together. 6. However, they have an optimistic view about kindergarten education (10 years later) which could be developed mainly by payment increase ans training qualified teachers.

Ogive-Cylinder 형 첨두부를 갖는 유도무기 주위 고앙각 흐름에서의 비대칭 와류 특성과 이에 따른 측력발생에 대한 수치적 해석 연구

정성기,제상언,명노신,조태환 慶尙大學校 經營行政大學院 2004 工學硏究院論文集 Vol.20 No.-

The demand for continually increased performance of missiles and aircraft leads to considering flight at very high angle of attack where control is very difficult. This is mainly due to shedding of asymmetric vortices from the forebody, producing side forces even at zero sideslip. In this paper, Computational Fluid Dynamics(CFD) was used to analyze characteristic of asymmetric vortices and examine the effects of several cases for rising asymmetric vortices. There are asymmetric grid cluster, sideslip angle and roughness. As a result of the study, asymmetric vortices were sensitive at the areas of roughness and the analysis results coincided with the experiment results at the specified area.

Detection of Hepatitis B virus DNA in Human Serum by Dot Hybridization Using a Biotin-Labelled Probe

Im Hwan Roe,Jung Hye Roe,Dong Hoo Lee 대한내과학회 1988 The Korean Journal of Internal Medicine Vol.3 No.1

Biotin 표지 HBV DNA 를 이용한 Dot Hybridization 에 관한 연구

노임환(Im Hwan Roe),이동후(Jung Hye Roe),노정혜(Dong Hoo Lee) 대한소화기학회 1988 대한소화기학회지 Vol.20 No.3

N/A A dot blot hybridization technique utilizing a biotin-labelled recombinant DNA probe was used to examine hepatitis B virus (HBV) DNA in serum. The lowest amount of HBV DNA in serum detectable by the color development of an avidin-biotin alkaline phosphatase complex was 40 picogram per 50 microliter. Validity of this method was confirmed by autoradiography using 32P-labelled and 3H-labelled HBV DNA probes. HBV DNA was found in 100% (34/34) of the HBsAg-positive and in 73.5% (25/34) of the HBsAg-negative subjects. In contrast, all nine cases showing negativity in HBV DNA were also HBsAg-negative. Correlation of Hbe antigen/antibody with HBV DNA was investigated in 19 sera of which HBsAg was negative but anti-HBc positive. Of 13 sera with anti-Hbe 10 (76.9%) cases revealed HBV DNA positivity, while four (66.7%) of six sera without anti-HBe were positive in HBV DNA. In conclusion, serum dot hybridization assay utilizing a bir>tinylated probe proved useful in the detection of a free form of HBV DNA regardless of the presence of HBsAg and irrespective of HBeAg-anti-HBe status. Also an anti-HBs does not always correspond to the clearance of HBV. And this indicates, in turn, that the potential infectivity of certain sera previously considered to be safe should be kept in mind. Moreover, it is emphasized that practical advantages in speed, reproducibility, and safety have made this alternative even more attractive than autoradiography using radioisotope- labelled probes.

The Digital Fabric of the World : Gibson`s Posthuman Vision in Idoru 깁슨의 아이도루에 나타나는 포스트휴머니즘

Roe, Jae H. 한국아메리카학회 2002 美國學論集 Vol.34 No.1

p53 STABILIZATION AND TRANSACTIVATION BY A VON HIPPEL-LINDAU PROTEIN

Roe, Jae-Seok,Kim, Hyungsoo,Lee, Soon-Min,Youn, Hong-Duk 이화여자대학교 세포신호전달연구센터 2006 고사리 세포신호전달 심포지움 Vol. No.8

von Hippel-Lindau(VHL) disease is a rare autosomal dominant cancer syndrome. Although hypoxia inducible factor-α(HIF-α) is a well-documented substrate of a von Hippel-Lindau tumor suppressor protein(pVHL), it remains controversial as to whether the dysregulation of HIF is sufficient for de novo tumorigenesis in VHL-deleted cells, which suggests that pVHL may have HIF-independent tumor suppressor functions. Here we found that pVHL directly associates with and stabilizes p53 by suppressing the mdm2-mediated ubiquitination and nuclear export of p53. Moreover, upon genotoxic stress, pVHL invoked a synergistic interaction between p53 and p300, and thus the acetylation of p53, which ultimately led to increasing p53 transcriptional activity and p53-mediated cell cycle arrest and apoptosis. This mechanism suggests that the tumor suppressor pVHL has an unexpected function to upregulate another tumor suppressor p53.

Louder than a Bomb : The Cultural Politics of Hardcore Rap in the U.S. and Korea

Roe, Jae H. 한국아메리카학회 2001 美國學論集 Vol.33 No.2

von Hippel–Lindau protein promotes Skp2 destabilization on DNA damage

Roe, J-S,Kim, H-R,Hwang, I-Y,Cho, E-J,Youn, H-D Macmillan Publishers Limited 2011 Oncogene Vol.30 No.28

Germline mutations in the von Hippel–Lindau (VHL) tumor suppressor gene cause VHL disease, a rare and autosomal-dominant genetic syndrome. Because VHL protein (pVHL) is the master regulator of hypoxia-inducible factor alpha (HIFα), the most prominent feature of VHL disease is the deregulation of HIFα proteins. However, the precise mechanism by which the loss of pVHL function contributes to tumorigenesis is not fully understood. Here, we show that pVHL destabilizes the F-box protein Skp2, a chief component of Skp, Cullin, F-box-containing complex that promotes DNA synthesis in the S phase. The β-domain of pVHL interacts with Skp2, stimulating proteasome-dependent Skp2 degradation, but the destabilization of Skp2 does not depend on the E3 ubiquitin ligase activity of pVHL. Notably, the generation of DNA damage induces Skp2 degradation, which is attenuated by the suppression of endogenous pVHL expression. One possible mechanism of pVHL-dependent Skp2 degradation entails the antagonizing of Akt-mediated Skp2 phosphorylation, which maintains Skp2 stability. Reintroduction of VHL into VHL-null renal cell carcinoma (RCC) cells decreased Skp2 levels and restored DNA damage-dependent Skp2 degradation. These results identify the tumor suppressor function of pVHL in delaying the S-phase progression to inhibit cell proliferation on DNA damage. Clinically, this report explains as to why Skp2 accumulates abnormally in RCC tissues.

(POST)COLONIAL RACISM, (POST)MODERN IDEOLOGICAL DISCOURSE

Roe, Jae H. 한국아메리카학회 1998 美國學論集 Vol.30 No.2

Memory and "Scraps of Truth" : Tim O`Brien`s Vietnam War Narratives 팀 오브라이언의 베트남전쟁 내러티브

Roe, Jae H 한국현대영미소설학회 2001 현대영미소설 Vol.8 No.1

본 논문은 베트남전쟁을 다룬Tim O'Brien의 작품들 - If I Die in a Combat Zone, Going After Cacciato, The Things They Carried - 에서 나타나는 베트남전쟁의 현실과 실험적인 서술방식을 논의한다. O'Brien의 작품들에는 내러티브의 형태와 베트남전쟁에 대한 작가의 시각이 불가분의 관계를 이루고있다. 전쟁당시 보병으로서의 경험을 재조명하는 과정에서, O'Brien은 미국인들이 잊어서는 안될 역사적인 교훈을 강조한다. Edward Herman과 Noam Chomsky는 베트남전쟁의 역사를 미국 제국주의와 민족학살의 역사로 설명한다. 또한, 이러한 역사가 미국매스미디어에 의해 의도적으로 변경되어서 미국인들이 베트남전쟁에 대해 잘못된 인식을 가지게 되었다고 주장한다. Jim Neilson은 이러한 잘못된 역사의식이 베트남전쟁문학에서도 나타난다고 주장한다. 이러한 현상은 문학작품들보다도 문학비평을 통해서 이루어졌다는 논지이다. 평론가와 학자들이 베트남전쟁 문학을 비역사적인, 미학적인 관점에서 분석해왔으며, 특히 역사적 현실을 불투명하게 만드는 postmodernism적인 이론에 의존하는 경향이 문제라고 지적한다. O'Brien의 작품들도 이러한 관점에서 분석되어왔는데, 본 논문은 이 작품들의 미학적, 문학이론적 측면보다는 역사적, 정치적 측면을 강조한다. 소설과 논픽션의 구분이 불투명한 O'Brien의 작품들에서 볼 수 있는 서술방식은 단지 문학적인 실험이 아니라 작가의 경험을 통해 베트남전쟁의 역사를 재조명하는 정치적인 의도가 있다는 것이 본 논문의 논지이다.