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Oliver Berberich,Julia Blöhbaum,Stefanie Hölscher-Doht,Rainer H. Meffert,Jörg Teßmar,Torsten Blunk,Jürgen Groll 한국공업화학회 2019 Journal of Industrial and Engineering Chemistry Vol.80 No.-
Tissue adhesives play an important role in clinical applications and may aid in the treatment of cartilagedefects for improved cartilage integration. However, many fail to satisfy the demand for adequateadhesive strength on wet tissue surfaces and to facilitate sufficient cell migration and extracellular matrix(ECM) deposition at the defect site. Utilizing poly(2-alkyl-2-oxazoline) (POx)-based polymers equippedwith mussel-inspired adhesion moieties and combining them with the natural wound sealantfibrinogen,we fabricated an adhesive biosynthethic hydrogel with tunable mechanical properties and improvedbonding strength. Degradation of the hydrogels could be adjusted by the ratio of amide to ester linkagesof the catecholic functional group at the POx side chain. In an in vitro disc/ring model for lateral cartilageintegration, a benefit in long-term integration was observed with enhanced degradation of the adhesivewithout the expense of bonding strength. Incorporation of degradable ester linkages in the polymerfacilitated cell invasion and strong deposition of cartilaginous ECM at the defect site. Overall, the resultssuggest that the presented injectable adhesive hydrogel, due to its easy tunability, holds great potentialfor cartilage defect treatment and other medical applications.
Role of biotechnology in rice breeding strategy of the Philippines
Oliver Escano Manangkil,Sailila Estilong Abdula,Eduardo Jimmy Pua Quilang 한국식물생명공학회 2020 Plant biotechnology reports Vol.14 No.2
The breeding strategy implemented by the Philippine Rice Research Institute (PhilRice) is anchored in Agriculture 4.0 that aims to revolutionize the variety development system of the Philippines, thereby addressing the grand challenges the rice industry facing at present and in the future, considering the struggles of a sustainable agriculture in the face of global warming. It advocates a stronger and more cohesive variety development structure to keep up with the need of the times as well as climate change. Our breeders are challenged to produce a variety that will double the yield at the same time, climate and pest resistant with good eating quality and nutritious. Strategies implemented by PhilRice include the use of advanced methodologies in biotechnology and molecular biology as tools in developing rice varieties to hasten crop improvement, thereby addressing the grand challenges the rice industry facing at present and in the future.
Oliver Gembruch,Elias Lemonas,Yahya Ahmadipour,Ulrich Sure,Nicolai El Hindy,Richard Dodel,Oliver Müller 대한척추신경외과학회 2019 Neurospine Vol.16 No.2
Objective: Demographic changes have led to a higher incidence of C-2 fractures, especially in elderly patients. For patients with type II fractures, treatment remains controversial, as discussed by Anderson and D’Alonzo, due to the rising morbidity and mortality rates for any treatment. The aim of this study was to compare conservative and surgical management in patients with type II C-2 fractures regarding outcomes, complications, and the mortality rate. Methods: A retrospective analysis was performed of the medical records, X-rays, and/or computed tomography scans of patients ≥80 years of age with type II fractures who were admitted to our Department of Neurosurgery between January 1990 and December 2017. The success of treatment was evaluated 3 months after surgery. Results: In total, 125 patients were included, of whom 98 were treated surgically and 27 were treated conservatively. Surgical treatment was successful in 90.8% of cases, while conservative treatment was successful in 70.0%. The in-hospital mortality was 14.29% and the 3-month mortality was 27.8% in the surgical group, compared to 3.7% and 20% in the conservatively treated group. The in-hospital complication rate was 22.4% in the surgically treated patients and 7.4% in the conservatively treated patients. Conclusion: Surgical treatment of type II fractures seemed to be associated with higher success and complication rates than conservative treatment. Nevertheless, 3-month mortality was comparable in both groups. Therefore, we conclude that surgical treatment for type II fractures in elderly patients is superior to conservative management, although conservative treatment remains a valuable option in elderly patients with severe comorbidities.
두 개의 중첩 레이저 빔을 사용하여 구리 헤어핀의 레이저 용접에서 스패터와 기공의 감소
Oliver Bocksrockera,Nicolai Spekera,Matthias Beraneka,Tim Hessea 한국레이저가공학회 2020 Laser Solutions Vol.23 No.12
헤어핀 기술은 e-Mobility 자동차 부문의 파워 트레인 효율성을 높이기 위한 e-Drive 제조에 새로운 수준의 자유를 제공한다. 구리 헤어핀의 레이저 용접에 대한 실험적 조사를 통해 소위 “2in1-fiber”를 이용한 중첩된 레이저 빔(BrightLine Weld)의 특정 빔 프로파일이 키홀을 안정화시켜 결과적으로 스패터와 기공을 감소시킨다는 것을 알아냈다. 스패터 정량화를 위해 프로세스의 고속 동영상이 사용되었다. 용접 중 기공 생성은 온라인 xRay-imaging을 통해 조사되었다. 관찰에 따르면, 중첩된 레이저빔이 사용될 경우 키홀의 크기가 넓어지는 것으로 나타났다. 그 결과, 키홀의 형태가 시간이 경과함에 따라 안정화되었다. 또한 키홀 형태 덕분에 증발된 물질의 증기를 수월하게 제거할 수 있다. 후자는 키홀이 부푸는 것을 억제하며 따라서 헤어핀 용접 프로세스 중에 스패터와 기공이 형성되는 것을 0에 가깝게 줄일 수 있다.
Global politics : Emerging Powers and Status: The Case of the First BRICs Summit
( Oliver Stuenkel ) 경남대학교 극동문제연구소 2014 ASIAN PERSPECTIVE Vol.38 No.1
Why did the leaders of four very different countries-Brazil, Russia, India, and China-decide to hold a summit in 2009 in Yekaterinburg, thus transforming "the BRICs" from a financial category into a political grouping? I argue that the main driver for the first summit to take place and succeed was to strengthen each member country`s international status. The 2009 BRICs summit was successful in that it led to the birth of a political platform during highly unusual international economic and political circumstances. In a global economy in the midst of a recession and widespread uncertainty, the BRICs` relative economic stability and capacity to respond to the crisis was decisive and lent credibility to their call for reform of the international system. The United States` temporarily reduced legitimacy also provided a window of opportunity for emerging powers to act as aspiring guarantors of stability in tomorrow`s world. While measureable gains from cooperation and stronger rhetoric that delegitimized the global order did occur in the following years, they were not the primary drivers for the first summit to take place and succeed. KEYWORDS: BRICs, emerging powers, status, BRICS.