ADVERSE EVENT REPORTING PROGRAM FOR HEALTH FUNCTIONAL FOOD IN NIFDS/KFDA

Myungsil Hwang,Young Hoon Kim,Hae Hyun Kim,Jin Hye Ha,Ja Young Kim,Junghoon Jang,Soon Young Han,Kwan Sung Kim 한국환경독성학회 2009 한국독성학회 심포지움 및 학술발표회 Vol.2009 No.11

Risk Assessment Principle for Engineered Nanotechnology in Food and Drug

Myungsil Hwang,Eun Ji Lee,Se Young Kweon,Mi Sun Park,Ji Yoon Jeong,Jun Ho Um,Sun Ah Kim,Bum Suk Han,Kwang Ho Lee,Hae Jung Yoon 한국독성학회 2012 Toxicological Research Vol.28 No.2

While the ability to develop nanomaterials and incorporate them into products is advancing rapidly worldwide, understanding of the potential health safety effects of nanomaterials has proceeded at a much slower pace. Since 2008, Korea Food and Drug Administration (KFDA) started an investigation to prepare “Strategic Action Plan” to evaluate safety and nano risk management associated with foods, drugs, medical devices and cosmetics using nano-scale materials. Although there are some studies related to potential risk of nanomaterials, physical-chemical characterization of nanomaterials is not clear yet and these do not offer enough information due to their limitations. Their uncertainties make it impossible to determine whether nanomaterials are actually hazardous to human. According to the above mention, we have some problems to conduct the human exposure risk assessment currently. On the other hand, uncertainty about safety may lead to polarized public debate and to businesses unwillingness for further nanotechnology investigation. Therefore, the criteria and methods to assess possible adverse effects of nanomaterials have been vigorously taken into consideration by many international organizations: the World Health Organization, the Organization for Economic and Commercial Development and the European Commission. The object of this study was to develop risk assessment principles for safety management of future nanoproducts and also to identify areas of research to strengthen risk assessment for nanomaterials. The research roadmaps which were proposed in this study will be helpful to fill up the current gaps in knowledge relevant nano risk assessment.

Current Trends in Developing Advanced Technologies for Risk Assessment and International Organization

Myungsil Hwang,Young Na Yum,Tae Moo Yoo,Dong Sup Kim,Sue Nie Park(박순희) 환경독성보건학회 2008 한국독성학회 심포지움 및 학술발표회 Vol.- No.-

Introduction for Chemical Risk Assessment in Food Safety Management

Myungsil Hwang 한국식품영양과학회 2019 한국식품영양과학회 학술대회발표집 Vol.2019 No.10

Antimetastatic Effects of Capsaicin in Murine B16 Melanoma Cell Lines

MyungSil Hwang,YoungNa Yum,Hoil Kang,Ok-Hee Kim 한국환경성돌연변이발암원학회 2005 한국환경성돌연변이·발암원학회지 Vol.25 No.1

The present work was undertaken to evaluate the antimetastatic potential of capsaicin (8-methyl-N-vanillyl-6-nonenamide) by measuring its effects on matrix metalloproteinase activity, cell invasion and lung metastasis. Significant inhibition of matrix metalloproteinase-2 activity by capsaicin (100 μM) was detected by gelatin zymography. In vitro invasion assay showed capsaicin (50, 100 μM) reduced tumor cell invasion (28-40%). Capsaicin (i.p., 2.5 mg/kg) inhibited development of lung colonization (58%). These results suggest that capsaicin prevents metastasis in part through suppression of invasion of B16F10 melanoma cells by inhibiting matrix metalloproteinase-2 responsible for degradation of extracellular matrix.

인체적용제품에 포함된 유해물질에 대한 식품의약품안전평가원의 인체 위해성평가

황명실(Myungsil Hwang),박유경(You-Gyoung Park),최희주(Heeju Choi),전우진(Woo-Jin Jeon),구용의(Yong Eui Koo) 환경독성보건학회 2019 한국독성학회 심포지움 및 학술발표회 Vol.2019 No.4

Women’s Subjective Worship Participations in Ancient Israel

Kim, Myungsil 한국실천신학회 2011 신학과 실천 Vol.0 No.29

Biblical narratives in the Old Testament and archeological evidences related to ancient Israelite lives proposes that ancient Israelite women were equally included in all the cultic activities and took some official roles, further some leading roles in the cult. Some differences between the cultic regulations for man and woman should be understood that they reflected their living conditions and socio-cultural phenomenon. No sexual discrimination against women is founded though the biblical witnesses are limited by the androcentric perspectives. As a member of covenantal community, woman could not be excluded. It is clear that the Deuteronomic family laws presuppose that male is the head of the family. However, it does not mean that the power and authority of the male head of household is unlimited. Although women’s decisions are dependence on men’s decision in some laws, it comes from consideration for a family’s social and economic well-being. Therefore, when we read the Deuteronomic family laws, we should mind the sociological perspective in our mind, not just literal understanding. To preserve their economic and territorial condition, which was acquired earned by the sweat of one’s brows, is the main purpose of their family legislation. One of the chief aims of Israelite law is to assure the integrity, economic stability of the family as the basic unity of society. When we examine the Israelite cultic laws, we can recognize that the congregation of YHWH includes the family and neither age nor sex bestow any special privileges, and there are the equal chances of women for participating in Israelite cultic events in the Old Testament and some cultic laws that obviously express the equal obligation or right for the cult for both, men and women. We can not imagine that without wives and mothers the family-centered cultic festivals would be possible. Women were only omitted by male elite biblical writers, not excluded or eliminated. The most important thing in the women’s purification regulations is that woman should be presented as individual and subject for the ritual, not by any male representative of the family. Besides women’s purification rituals and the Israelite cultic feasts that all people attended, there are many cultic activities done voluntarily by Israel women in the Old Testament. When we examine these activities, we can see that women were not much more disadvantaged in communal religious activity than general(non-priestly) males. The richest portrait of women in leadership roles is shown in the literature pertaining to the pre-monarchic period. In the monarchical period, Israel’s cultic activities became centralized and standardized in Jerusalem Royal Temple. Consequently, many cultic activities done by women in the shrines or the houses, in which pre-monarchial women were active and used to take the leading roles like Deborah, Miriam, Hannah or the mother of Micah (Jud.17), became weak. Nevertheless, during the monarchial period some women took the official place in the public worship such as women choir, women who served in the temple, or prophetesses. Therefore, in spite of some different regulations between sexes in the family cultic laws we should not regard it as discrimination or prohibition against women’s cultic participation. Although the different sociological conditions in the history had made women’s religious status changed, but women were always successful to continue their religious lives as the subjects, and will never stop doing it.

메이지 초기 일본의 미션스쿨

이명실(Lee, Myungsil) 교육사학회 2009 교육사학연구 Vol.19 No.1

본 연구에서는 메이지 초기 일본에 존재한 교파 가훈데 개혁ㆍ장로파와 감리파 교회가 세운 학교, 즉 메이지 학원과 아오야마 학원의 설립 과정과 거기서 나타나는 특징에 관해 고찰한다. 일본의 메이지 정부는 1880년 교육령 개정 1886년 학교령 등을 통해 미션 스쿨의 설립이나 변경을 신고제에서 허가제로 바꾸는데, 이는 일본 정부가 미션 스쿨에 대해 주목하기 시작했음을 의미한다. 지금까지의 연구에서는 1880년대 중반 이후 천황제 이데올로기 보급을 위한 교육정책의 보수화와 이에 따른 미션 스쿨과의 갈등과 타협의 과정에 초점을 두었다. 본 연구에서는 교육과 종교와의 갈등과 대립이 표면화되기 전, 비교적 자유로운 교육활동을 전개할 수 있었던 1880년 중반 이전에 미션 스쿨이 교단 내 통합의 과정을 거쳐 점차 체계적이고 조직적인 학교의 모습으로 발전해 갔다는 점과 그 과정에서 나타난 선교사들의 활동을 구체적으로 제시한다. This study examined the characteristics of the development of Japanese mission schools in the early Meiji period, focusing on Meiji Gakuin(明治學院) and Aoyama Gakuin(靑山學院). Features of educational policies of Japanese government and instructional services of the missionaries in the period of “Meiji 10s,” characterized as Westernized Period, were investigated. Following issues were identified: a) Missionaries from various religious associations contributed to educating Japanese people and producing national leaders while satisfying their religious purposes through education; b) It does not appear that their educational activities were performed systematically and active so that their missionary work could influence Japanese society; c) The missionaries from the Reformed & Presbyterian churches were involved in various performances, including translations, writings, and medical services while the Methodists focused on education; d) The Reformed & Presbyterian churches and the Methodist churches constructed schools through the unification of their own denominations, which caused confirming two churches’ different religious pursuits for their missionary work.

『교육시론(敎育時論)』의 구성 및 성격 - ‘일본인의 조선교육 인식’ 분석을 위한 시론 -

이명실 ( Lee Myungsil ) 한국교육사학회 2018 한국교육사학 Vol.40 No.4

『교육시론』은 1885년부터 1934년까지 일본에서 발행되었던 잡지였다. 1호부터 1762호까지 매달 3회 발행된 잡지에는 일본에서 활동하는 교육가, 학자, 교육관료, 정치관료 등이 필진으로 등장했고, 당시 현안이었던 교육정책 및 교육사상뿐 아니라 교육관련 출판물 등에 관한 내용이 포함되었다. 이와 함께 『교육시론』에는 조선 및 한국교육에 관한 글이 적은 수이기는 하지만 실려 있었다. 잡지에 게재된 글은 학부나 조선총독부가 간행한 정책문서보다 일본 내 일반 독자들에게 훨씬 더 다가가기 쉽고 파급력을 가질 수 있었다는 점에서 중요한 분석의 대상이 될 수 있다. 이러한 문제 의식 아래 본 연구에서는 『교육시론』의 출간 의도 및 구성에 관한 전반적인 사항을 논의한 후, 이 잡지에 실린 조선 및 한국교육 관련 기사의 양적 추이에 관해 살펴보았다. 이를 통해 i) 『교육시론』은 페스탈로치의 개발주의를 근간으로 하는 교육시사 잡지의 성격을 지녔으며 종간될 때까지 자신들의 논조를 유지했다는 점, ii) 『교육시론』의 지면 구성은 시대의 변화에 따라 달라졌지만 당시의 교육현안이나 국내외 교육동향 및 시대상을 반영하는 내용으로 이루어졌다는 점, iii) 『교육시론』에 게재된 조선 및 한국교육 관련 글이 양적으로 많다고 보기 어렵지만 일본의 일반 독자들에게 정보제공자로서의 역할을 했다는 점 등을 제시하였다. KyouikuJiron was a educational magazine published in Japan form 1885 to 1934. In the magazine which had been published three times a month, from vol.1 to vol.1762, many articles were written by Japanese educators, scholars, and educational officials were contained. And the contents of articles contained information about educational publications and literary works such as novels and poetry, as well as educational thoughts, educational system, and educational policies. The magazine, which had been published for 50 years, was one of the oldest magazine published Japan at that time. In this regard, the magazine which had been published through Meiji, Daisyo, and Showa period, serves as a first source in understanding the government’s education policy and opinions of various groups. The magazine also had included Japanese writing about Korea and Korean education at that time. The articles in the magazine were much more accessible to the general reader than the government-published work, so that they had influence. In this paper, I will examine the whole organization and nature of the magazine, and then examine the characteristics of articles about Korea and Korean education. This paper will serve as a preparatory work to review the Japanese perception of Korea and its education.

일본의 교육칙어 수정론에 관한 일 고찰

이명실 ( Lee Myungsil ) 한국교육사학회 2016 한국교육사학 Vol.38 No.4

본 논문에서는 일본에서 교육칙어가 발포된 이래 제안되었던 교육칙어의 개정·보완 및 철회에 관한 논의의 양상과 그 논리에 관해 고찰하는 것을 목적으로 했다. 교육칙어는 1890년 그것이 발포되기까지 일본이 처해있던 정치·사회·경제적 상황을 바탕으로 성립된 것인데, 이후 일본의 국내외적 상황은 산업자본주의의 발흥과 두 번에 걸친 전쟁의 승리로 급변하고 있었다. 이에 당시 정치관료 및 지식인 가운데는 국민통합 이데올로기로서의 교육칙어를 변화하는 세계에 통용될 수 있도록 재구성해야 한다는 의견을 제안하거나 이에 동조하는 이들이 있었다. 그러나 이러한 구상에 대해 보수파 및 국수주의자들은 비판하는데 머물지 않고 `불경` 사건으로 전화시키거나 있지도 않은 사건을 허위 보도하는 방법을 통해 자신들의 논리를 강화시켜 나갔다. 이 과정에서 교육칙어 수정의견을 제안했던 정치관료 및 지식인은 사회적 지탄의 대상이 되었고 자신의 주장을 철회하지 않을 수 없었다. 교육칙어의 개정·보완 및 철회에 대한 의견과 그것이 수습되어가는 상황을 다룬 본 논문에서는 이데올로기적 통합장치로서 큰 역할을 했던 교육칙어가 당위로서 주어진 것이 아니라 다양한 집단의 이해관계가 갈등·대립하며 절대적 권위를 갖게 되는 과정을 다루었다. 이는 메이지 시기 이후 일본적 근대의 성격을 밝히는 과정임과 동시에 일제강점기 식민지 교육정책의 성격을 규명하기 위한 작업이라는 점에서 의미가 있다. In this paper, I focus on the discussion of modifications of the Imperial Rescript on Education in Japan. The Imperial Rescript on Education was established under the social, political and economical environment of Japan in 1890. After that, the country underwent a sudden change with the rise of industrial capital and victories in the Sino-Japanese War and the Russo-Japanese War. Under these circumstances, some politicians and intellectuals thought the Imperial Rescript on Education should be amended or revised. They hoped that it could become an international ideology. But these ideas were criticized by the Conservatives and Ultra-nationalists, and the Conservatives and Ultra-nationalists strengthened their argument by circulating FukeiJiken(lese-majeste affairs) or rumors. Consequentially, some politicians and intellectuals became a target of criticism from the public. In this paper, I analyze the ideas of modifications of the Imperial Rescript on Education and their development and logics. The authority of the Imperial Rescript on Education that played the role of an ideological integration in Japan was not given as “is” but was won through conflicting interests of various groups. Through this paper, I clarified the characteristics of Japanese modern education and the colonial education system of Japan in Korea.