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백화점 뉴실버여성 의류매장 VMD에 대한 연구 : 중국 의류매장에 대한 제안
LiQin,최정선(Choi Jung-Sun),김완민(Kim Wan-Min) 동북아시아문화학회 2009 동북아시아문화학회 국제학술대회 발표자료집 Vol.2009 No.5월
Visual merchandising (VMD hereafter) has become a more important issue because it plays a vital role in promoting a company’s image and increasing sales. The purpose of this study is to investigate the effects of VMD image on new elderly female consumers’ purchasing behavior. The subjects of the study were 150 elderly customers aged from 50 to 65 in Dalian, China who are called the 'new silver generation’.A survey was conducted to find out consumer attitudes towards the VMD of department stores and their purchasing behavior. The collected data was analyzed with frequency analysis. Through the results of the analysis, the following findings were discovered: First, the new elderly consumers showed a positive attitude toward the VMD of department stores so it seems important for retailers to make effective VMD methods for them as well as for younger consumers. Second, the new elderly consumers' preference for bright colors seems to reflect the fact that they always want to try to look younger, so the VMD display should use brighter colors. Third, as these elderly consumers grow older, their height tends to gradually shrink. Thus, the hanger height of department stores for them should be reduced accordingly, that is, 4-8 cm lower than ordinary hanger heights. Fourth, the shops which consider them as target customers must provide rest areas for them in the stores. As these elderly customers have the habit of shopping with a frequent need for sitting, it is important to make the face out presentation around the store. Based on the results of the survey analysis of the VMD aspect of the Lotte Department Store in Korea and Dalian Department Store in China, efficient VMD methods have been proposed to promote clothing sales for the elderly in the region.
LiQin Zhu,JianWei Yang,Yuan Zhang,YongMing Wang,JianLei Zhang,YuanYuan Zhao,WeiLin Dong 대한약리학회 2015 The Korean Journal of Physiology & Pharmacology Vol.19 No.2
The aim of this study is to develop a physiologically based pharmacokinetic (PBPK) model in intraabdominalinfected rats, and extrapolate it to human to predict moxifloxacin pharmacokinetics profilesin various tissues in intra-abdominal infected human. 12 male rats with intra- abdominal infections,induced by Escherichia coli, received a single dose of 40 mg/kg body weight of moxifloxacin. Bloodplasma was collected at 5, 10, 20, 30, 60, 120, 240, 480, 1440 min after drug injection. A PBPK modelwas developed in rats and extrapolated to human using GastroPlus software. The predictions wereassessed by comparing predictions and observations. In the plasma concentration versus time profileof moxifloxcinin rats, Cmax was 11.151 μg/mL at 5 min after the intravenous injection and t1/2 was2.936 h. Plasma concentration and kinetics in human were predicted and compared with observed datas. Moxifloxacin penetrated and accumulated with high concentrations in redmarrow, lung, skin, heart,liver, kidney, spleen, muscle tissues in human with intra-abdominal infection. The predicted tissue toplasma concentration ratios in abdominal viscera were between 1.1 and 2.2. When rat plasma concentrationswere known, extrapolation of a PBPK model was a method to predict drug pharmacokineticsand penetration in human. Moxifloxacin has a good penetration into liver, kidney, spleen, as well asother tissues in intra-abdominal infected human. Close monitoring are necessary when using moxifloxacindue to its high concentration distribution. This pathological model extrapolation may provide referenceto the PK/PD study of antibacterial agents.
Liqin Tang,Haocheng Liu,Manqin Fu,Yujuan Xu,Jing Wen,Jijun Wu,Yuanshan Yu,Xian Lin,Lu Li,Zhibin Bu,Wanyuan Yang 한국식품과학회 2022 Food Science and Biotechnology Vol.31 No.11
The preparation process of yellow pigment (YP) from gardenia (Gardenia jasminoides) fruit was investigated, and the main components of YP were characterized by liquid chromatography-time of flight-mass spectrometer/mass spectrometer (LC-TOF–MS/MS). Furthermore, cytotoxic activity in HepG2 cells by induction of apoptosis was also evaluated. The preparation results indicated that the color value of YP was 498.34, which was 8.6 times higher than crude YP. Fifteen compounds in YP were identified, and crocins were the predominant compounds. The cell experiment results showed that YP inhibited the proliferation of HepG2 cells in a time- and dose-dependent manner. Moreover, YP also inhibited HepG2 cells in G2/M stage, increased the level of intracellular reactive oxygen species (ROS), and enhanced cell apoptosis. Real-time quantitative polymerase chain reaction (RT-PCR) analysis revealed the up-regulation of caspase-3, 8, 9, and bax and down-regulation of bcl-2 in HepG2 cells. Overall, these findings suggested that YP had potential cytotoxic activity in HepG2 cells by induction of apoptosis, which might be beneficial to human health.
Hu, Liqin,Zhou, Tingting,Feng, Jingwen,Jin, Hua,Tao, Yun,Luo, Dan,Mei, Surong,Lee, Yong-Ill Elsevier 2018 Journal of Electroanalytical Chemistry Vol.813 No.-
<P><B>Abstract</B></P> <P>Azithromycin (AZM) is a widely used macrolide antibiotic to treat infections caused by bacteria. Considering the side-effect to human health, a rapid and selective electrochemiluminescence (ECL) sensor was fabricated on the basis of molecularly imprinted polymer (MIP) modified carbon paste electrode as a recognition element. We systematically optimized the factors influencing the processes on the extraction and determination for AZM, including the amount of MIP power and paraffin oil, extraction solution, extraction time and the pH of Ru(bpy)<SUB>3</SUB> <SUP>2+</SUP> solution. Under the optimal condition, the wide linear range was observed from 1.0 × 10<SUP>−10</SUP> to 4.0 × 10<SUP>−7</SUP> mol L<SUP>−1</SUP>, and the limit of detection (LOD) was low as 2.3 × 10<SUP>−11</SUP> mol L<SUP>−1</SUP> (S/N = 3). The spiked recoveries of AZM in urine and blood samples were from 98.4% to 113.5% with RSD changing from 3.7% to 13.2%, respectively. The results of AZM determination by this proposed sensor were in accordance with that of high-performance liquid chromatography–tandem mass spectrometry method. Thus, the developed MIP-based ECL sensor will have a great potential application in rapid and sensitive determination of trace AZM in complex biological samples.</P> <P><B>Highlights</B></P> <P> <UL> <LI> ECL sensor </LI> <LI> MIP modified CP electrode </LI> <LI> Trace AZM determined in biological samples </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>
Zhu, LiQin,Yang, JianWei,Zhang, Yuan,Wang, YongMing,Zhang, JianLei,Zhao, YuanYuan,Dong, WeiLin The Korean Society of Pharmacology 2015 The Korean Journal of Physiology & Pharmacology Vol.19 No.2
The aim of this study is to develop a physiologically based pharmacokinetic (PBPK) model in intra-abdominal infected rats, and extrapolate it to human to predict moxifloxacin pharmacokinetics profiles in various tissues in intra-abdominal infected human. 12 male rats with intra- abdominal infections, induced by Escherichia coli, received a single dose of 40 mg/kg body weight of moxifloxacin. Blood plasma was collected at 5, 10, 20, 30, 60, 120, 240, 480, 1440 min after drug injection. A PBPK model was developed in rats and extrapolated to human using GastroPlus software. The predictions were assessed by comparing predictions and observations. In the plasma concentration versus time profile of moxifloxcinin rats, $C_{max}$ was $11.151{\mu}g/mL$ at 5 min after the intravenous injection and $t_{1/2}$ was 2.936 h. Plasma concentration and kinetics in human were predicted and compared with observed datas. Moxifloxacin penetrated and accumulated with high concentrations in redmarrow, lung, skin, heart, liver, kidney, spleen, muscle tissues in human with intra-abdominal infection. The predicted tissue to plasma concentration ratios in abdominal viscera were between 1.1 and 2.2. When rat plasma concentrations were known, extrapolation of a PBPK model was a method to predict drug pharmacokinetics and penetration in human. Moxifloxacin has a good penetration into liver, kidney, spleen, as well as other tissues in intra-abdominal infected human. Close monitoring are necessary when using moxifloxacin due to its high concentration distribution. This pathological model extrapolation may provide reference to the PK/PD study of antibacterial agents.
WANG, Liqin World Association for Triple Helix and Future Stra 2011 Journal of Contemporary Eastern Asia Vol.10 No.2
China's proposal of the CAFTA (China-ASEAN Free Trade Area) in 2001 prompted a great debate about whether China was a trade competitor of ASEAN, given their similarity in economic development levels and trade/export structures. That Beijing shifted its focus on economic cooperation from the international level to the regional level led to its proposal of the CAFTA. As the Framework Agreement (Framework Agreement on Comprehensive Economic Cooperation between China and ASEAN) showed, Beijing's careful consideration for four newer ASEAN members (Cambodia, Laos, Myanmar and Vietnam) intended not only to help all ASEAN members develop economically, but also to narrow the economic gap existing between them and the six old ASEAN members; in return, China was recognized as a full market economy, which it is not currently recognized within the framework of the WTO. The substantial rise in bilateral trade and the structural changes of the trade in goods between China and ASEAN member nations after 2001 proves that ASEAN benefited more from the CAFTA, particularly when the areas where ASEAN had the comparative advantages were designated as the priority cooperation areas between China and ASEAN. In sum, similarities existing in economic development levels and industrial structures between China and ASEAN made them natural economic competitors. However, closer studies of trade in goods of S1-7, S1-6 and S1-0 reveal that China acted as an increasingly complementary trade partner of ASEAN after 2001.
OSCILLATIONS OF CERTAIN NONLINEAR DELAY PARABOLIC BOUNDARY VALUE PROBLEMS
Zhang, Liqin,Fu, Xilin 한국전산응용수학회 2001 The Korean journal of computational & applied math Vol.8 No.1
In this paper we consider some nonlinear parabolic partial differential equations with distributed deviating arguments and establish sufficient conditions for the oscillation of some boundary value problems. AMS Mathematics Subject Classification : 34C10, 34K15