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      • KCI등재

        Chatbot Design Method Using Hybrid Word Vector Expression Model Based on Real Telemarketing Data

        ( Jie Zhang ),( Jianing Zhang ),( Shuhao Ma ),( Jie Yang ),( Guan Gui ) 한국인터넷정보학회 2020 KSII Transactions on Internet and Information Syst Vol.14 No.4

        In the development of commercial promotion, chatbot is known as one of significant skill by application of natural language processing (NLP). Conventional design methods are using bag-of-words model (BOW) alone based on Google database and other online corpus. For one thing, in the bag-of-words model, the vectors are Irrelevant to one another. Even though this method is friendly to discrete features, it is not conducive to the machine to understand continuous statements due to the loss of the connection between words in the encoded word vector. For other thing, existing methods are used to test in state-of-the-art online corpus but it is hard to apply in real applications such as telemarketing data. In this paper, we propose an improved chatbot design way using hybrid bag-of-words model and skip-gram model based on the real telemarketing data. Specifically, we first collect the real data in the telemarketing field and perform data cleaning and data classification on the constructed corpus. Second, the word representation is adopted hybrid bag-of-words model and skip-gram model. The skip-gram model maps synonyms in the vicinity of vector space. The correlation between words is expressed, so the amount of information contained in the word vector is increased, making up for the shortcomings caused by using bag-of-words model alone. Third, we use the term frequency-inverse document frequency (TF-IDF) weighting method to improve the weight of key words, then output the final word expression. At last, the answer is produced using hybrid retrieval model and generate model. The retrieval model can accurately answer questions in the field. The generate model can supplement the question of answering the open domain, in which the answer to the final reply is completed by long-short term memory (LSTM) training and prediction. Experimental results show which the hybrid word vector expression model can improve the accuracy of the response and the whole system can communicate with humans.

      • KCI등재

        Preventive Effect of Polysaccharide of Larimichthys crocea Swim Bladder on Reserpine Induced Gastric Ulcer in ICR Mice

        Gui-Jie Li,Peng Sun,Rui Wang,Yalin Zhou,Yu Qian,Xin Zhao 대한약리학회 2014 The Korean Journal of Physiology & Pharmacology Vol.18 No.2

        This project’s aim was to determine the reserpine-induced gastric ulcer preventive effect of polysaccharideof Larimichthys crocea swim bladder (PLCSB) in ICR mice. The anti-gastric ulcer effectsof polysaccharide of Larimichthys crocea swim bladder was evaluated in mice model using morphologicaltest, serum levels assay, cytokine levels assay, tissue contents analysis, reverse transcription-polymerase chain reaction (RT-PCR) analysis and western bolt assay. High concentration (50mg/kg dose) of PLCSB reduced IFN-γ as compared to low concentration (25 mg/kg dose) and controlmice. SS and VIP serum levels of PLCSB treated mice were higher than those of control mice, andMOT and SP serum levels were lower than control mice. Gastric ulcer inhibitory index of PLCSBtreatment groups mice were much lower than control mice, and the high concentration treated micewere similar to the ranitidine treated mice. The SOD and GSH-Px activities of PLCSB treated micewere higher than control mice, close to normal mice and ranitidine treated mice. PLCSB treated micealso showed the similar contents of NO and MDA to normal group. By RT-PCR and western blot assay,PLCSB significantly induced inflammation in tissues of mice by downregulating NF-κ B, iNOS, andCOX-2, and upregulating IκB-α . These results suggest that PLCSB showed a good gastric ulcerpreventive effect as the gastric ulcer drug of ranitidine. Polysaccharide of Larimichthys crocea swimbladder may be used as a drug material from marine products.

      • KCI등재

        Channel Fading Effect Analysis on Diffusion Cooperation Strategies over Adaptive Networks

        ( Jie Yang ),( Ehsan Mostafapour ),( Amir Aminfar ),( Jie Wang ),( Hao Huang ),( Afsaneh Akhbari ),( C. Ghobadi ),( Guan Gui ) 한국인터넷정보학회 2019 KSII Transactions on Internet and Information Syst Vol.13 No.1

        In this paper, we investigate the performance of the diffusion adaptation strategies for parameter estimation in wireless adaptive networks, where the nodes exchange information over noisy and fading wireless channels. This paper shows the differences between the effect of Rayleigh and Rician fading over wireless adaptive networks and proves that the Rician fading is a more practical model in such kinds of networks. Simulation results imply that the effect of Rayleigh fading is more degrading for the estimation process than Rician fading. Also, the simulation results show the performance of adapt then combine (ATC) diffusion algorithm is better than the combine then adapt (CTA) algorithm by merely considering noise in wireless channels. While the performance of CTA prevails ATC over the wireless adaptive network in the presence of noise plus channel fading.

      • KCI등재

        Antioxidant, Antimutagenic, and In vivo Buccal Mucosa Cancer Preventive Effects of Fructus Malvae

        Gui-Jie Li,Qiang Wang,Yu Qian,Xin Zhao 한국식품과학회 2014 Food Science and Biotechnology Vol.23 No.4

        Fructus Malvae is functional food known forantioxidant, anti-mutagenic, and in vivo anticancer effects. Fructus Malvae extracts demonstrated high antioxidantactivities in DPPH and hydroxyl radical scavenging activityassays. In an Ames mutagenicity test, Fructus Malvaeexhibited antimutagenicty in association with MNNG (Nmethyl-N'-nitro-N-nitrosoguanidine) in Salmonella TyphimuriumTA100 cells. U14 squamous carcinoma cells were injectedinto the buccal mucosa of KM (Kunming) mice. Thewound at the injection site was smeared with a FructusMalvae solution, which was also administered to mice bygavage. Tumor volumes were reduced and tissue sectionanalysis of buccal mucosa cancer and cervical lymph nodetissues showed anti-cancer effects in Fructus Malvaetreated groups. Fructus Malvae possesses good antioxidantand antimutagenic activities and exerts a preventive effectagainst buccal mucosa cancer in vivo.

      • KCI등재

        Preventive effect of Polysaccharide of Larimichthys Crocea Swimming Bladder on Activated Carbon- Induced Constipation in Mice

        Gui-Jie Li,Yu Qian,Peng Sun,Xia Feng,Kai Zhu,Xin Zhao 한국응용생명화학회 2014 Applied Biological Chemistry (Appl Biol Chem) Vol.57 No.2

        Effects of polysaccharide of Larimichthys croceaswimming bladder (PLCSB) on activated carbon-induced constipationin ICR mice were investigated. ICR mice were subjected to oraladministration with lactic acid bacteria for 9 days. Body weight,diet and drinking intake, defecation status, gastrointestinal transit,and defecation time, as well as motilin (MTL), gastrin (Gas),endothelin (ET), somatostatin (SS), acetylcholinesterase (AChE),substance P (SP), and vasoactive intestinal peptide (VIP) levels inserum were used to evaluate the preventive effects of PLCSB onconstipation. Bisacodyl, a laxative drug, was used as a positivecontrol. The time to the first black stool defecation for normal,control, bisacodyl-treated (100 mg/kg), 50 and 100 mg/kg PLCSBtreatedmice were 88, 202, 126, 155, and 135 min, respectively. Following the consumption of oral administration of 50 and 100mg/kg PLCSB or bisacodyl (100 mg/kg), the gastrointestinaltransit was reduced to 62.6, 78.3, and 90.2%, respectively. Theserum levels of MTL, Gas, ET, AChE, SP, and VIP weresignificantly increased, and the serum levels of SS were reducedin the mice treated with PLCSB compared with those in theuntreated control mice (p <0.05). These results demonstrate thatPLCSB has preventive effects on mouse constipation and highconcentration of that demonstrated the better functional activity.

      • SCIESCOPUSKCI등재

        Preventive Effect of Polysaccharide of Larimichthys crocea Swim Bladder on Reserpine Induced Gastric Ulcer in ICR Mice

        Li, Gui-Jie,Sun, Peng,Wang, Rui,Zhou, Ya-Lin,Qian, Yu,Zhao, Xin The Korean Society of Pharmacology 2014 The Korean Journal of Physiology & Pharmacology Vol.18 No.2

        This project's aim was to determine the reserpine-induced gastric ulcer preventive effect of polysaccharide of Larimichthys crocea swim bladder (PLCSB) in ICR mice. The anti-gastric ulcer effects of polysaccharide of Larimichthys crocea swim bladder was evaluated in mice model using morphological test, serum levels assay, cytokine levels assay, tissue contents analysis, reverse transcription-polymerase chain reaction (RT-PCR) analysis and western bolt assay. High concentration (50 mg/kg dose) of PLCSB reduced IFN-${\gamma}$ as compared to low concentration (25 mg/kg dose) and control mice. SS and VIP serum levels of PLCSB treated mice were higher than those of control mice, and MOT and SP serum levels were lower than control mice. Gastric ulcer inhibitory index of PLCSB treatment groups mice were much lower than control mice, and the high concentration treated mice were similar to the ranitidine treated mice. The SOD and GSH-Px activities of PLCSB treated mice were higher than control mice, close to normal mice and ranitidine treated mice. PLCSB treated mice also showed the similar contents of NO and MDA to normal group. By RT-PCR and western blot assay, PLCSB significantly induced inflammation in tissues of mice by downregulating NF-${\kappa}B$, iNOS, and COX-2, and upregulating $I{\kappa}B-{\alpha}$. These results suggest that PLCSB showed a good gastric ulcer preventive effect as the gastric ulcer drug of ranitidine. Polysaccharide of Larimichthys crocea swim bladder may be used as a drug material from marine products.

      • SCIEKCI등재

        Preventive effect of Polysaccharide of Larimichthys Crocea Swimming Bladder on Activated Carbon-Induced Constipation in Mice

        Li, Gui Jie,Qian, Yu,Sun, Peng,Feng, Xia,Zhu, Kai,Zhao, Xin The Korean Society for Applied Biological Chemistr 2014 Applied Biological Chemistry (Appl Biol Chem) Vol.57 No.2

        Effects of polysaccharide of Larimichthys crocea swimming bladder (PLCSB) on activated carbon-induced constipation in ICR mice were investigated. ICR mice were subjected to oral administration with lactic acid bacteria for 9 days. Body weight, diet and drinking intake, defecation status, gastrointestinal transit, and defecation time, as well as motilin (MTL), gastrin (Gas), endothelin (ET), somatostatin (SS), acetylcholinesterase (AChE), substance P (SP), and vasoactive intestinal peptide (VIP) levels in serum were used to evaluate the preventive effects of PLCSB on constipation. Bisacodyl, a laxative drug, was used as a positive control. The time to the first black stool defecation for normal, control, bisacodyl-treated (100 mg/kg), 50 and 100 mg/kg PLCSB-treated mice were 88, 202, 126, 155, and 135 min, respectively. Following the consumption of oral administration of 50 and 100 mg/kg PLCSB or bisacodyl (100 mg/kg), the gastrointestinal transit was reduced to 62.6, 78.3, and 90.2%, respectively. The serum levels of MTL, Gas, ET, AChE, SP, and VIP were significantly increased, and the serum levels of SS were reduced in the mice treated with PLCSB compared with those in the untreated control mice (p<0.05). These results demonstrate that PLCSB has preventive effects on mouse constipation and high concentration of that demonstrated the better functional activity.

      • KCI등재

        Flow separation control of two kinds of microvortex generators for a supersonic spinning projectile

        Jie Ma,Zhen-gui Huang,Zhihua Chen,Da-wen Xue,Jun-li Han 대한기계학회 2017 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.31 No.1

        Previous studies have shown that Microvortex generators (MVGs) can effectively control the flow separation of supersonic boundary layer. To improve the flight stability of a spinning projectile, two kinds of MVGs, micro ramps and vanes, are applied to control the flow separation of an original standard 155 mm projectile, respectively. Numerical simulations were performed with the use of Detached eddy simulation (DES) method, and the flow fields of the projectile with and without micro MVGs were simulated, the characteristics of the boundary layer and aerodynamic data of three cases were compared and discussed. The numerical results reveal that the effect of the MVGs control is obvious, but their mechanisms are different, and the vanes are more effective than the ramp in the boundary layer control. However, they can both improve the lift and pitching moment of the projectile, and eliminate their oscillations; as a result, its flight stability and firing dispersion can be enhanced. Our results can provide important guidance for improving the flight quality of supersonic projectiles.

      • KCI등재

        An Improved Method for Dewatering Sewage Sludge Using Intermittent Vacuum Loading with Wheat Straw as Vertical Drains

        Gui-zhong Xu,Jie Yin,Xu-Song Feng,Feng Ji 대한토목학회 2020 KSCE Journal of Civil Engineering Vol.24 No.7

        This paper presents an experimental investigation on the feasibility and effectiveness of an improved method for dewatering sewage sludge (SS) in landfills. Compared with traditional vacuum preloading with prefabricated vertical drains (PVDs), an improved intermittent vacuum loading with wheat straw vertical drains (WSVDs) was developed and a series of laboratory tests were conducted to evaluate the effects of WSVD type and intermittent loading period on the dewatering properties of SS. Tests results showed that the WSVD has a good elastic deformation characteristic during vacuum loading and unloading over PVD. The vacuum degree transmission tests on three types of WSVD showed that 5 cm crushed wheat straw is the optimum one. The surface settlement and water content of SS after the model test are similar for WSVD and PVD in the traditional vacuum consolidation method. There was a significant improvement when applying intermittent vacuum and optimum daily loading time of 10 hours was obtained. The cracks found in the sludge cake around the drainage body using improved method are suggested as the key factor since they are able to improve the vacuum transmission capacity and the permeability of SS. The improved method is expected to offer a feasible and cost-effective way to deal with high water content SS in landfills.

      • KCI등재후보

        Apriona germari Larval Cuticle Protein Genes: Genomic Structure of Three Cuticle Protein Genes and cDNA Cloning of a Novel Cuticle Protein

        ( Gui Zhong Zheng ),( Bo Yeon Kim ),( Hyung Joo Yoon ),( Ya Dong Wei ),( Guo Xi Jie ),( Byung Rae Jin ),( Hung Dae Shon ) 한국잠사학회 2007 International Journal of Industrial Entomology Vol.14 No.1

        In a previous study, three larval cuticle protein genes were cloned from the mulberry longicorn beetle, Apriona germari (Comp. Biochem. Physiol. B 136,803-811, 2003). In the present study, the genomic structures of these three larval cuticle protein genes (AgLCP9.2, AgLCP12.6 and AgLCP12.3) were elucidated. All three cuticle protein genes consist of one intron and two exons. Southern blot analysis of genomic DNA suggested that three cuticle protein genes are a single copy gene. In addition, a novel larval cuticle protein gene, AgLCP10.6, was cloned from A. germari in this study. The AgLCP10.6 cDNA contains an ORF of 300 nucleotides that are capable of encoding a 100-amino acid polypeptide with a predicted molecular mass of 10.6 kDa. The amino acid sequence deduced from the AgLCP10.6 cDNA contained a type-specific consensus sequence identifiable in other insect cuticle proteins and is most homologous to Drosophila melanogaster cuticle protein ACP65A (51 % protein sequence identity). Northern blot analysis revealed that AgLCP10.6 showed epidermis-specific expression.

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